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Protein

Nucleoside-triphosphatase THEP1

Gene

Mbar_A3054

Organism
Methanosarcina barkeri (strain Fusaro / DSM 804)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.UniRule annotation

Catalytic activityi

NTP + H2O = NDP + phosphate.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi8 – 15ATPUniRule annotation8
Nucleotide bindingi99 – 106ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMBAR269797:GHUW-3004-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoside-triphosphatase THEP1UniRule annotation (EC:3.6.1.15UniRule annotation)
Short name:
NTPase THEP1UniRule annotation
Alternative name(s):
Nucleoside triphosphate phosphohydrolaseUniRule annotation
Gene namesi
Ordered Locus Names:Mbar_A3054
OrganismiMethanosarcina barkeri (strain Fusaro / DSM 804)
Taxonomic identifieri269797 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
Proteomesi
  • UP000008156 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000469531 – 174Nucleoside-triphosphatase THEP1Add BLAST174

Interactioni

Protein-protein interaction databases

STRINGi269797.Mbar_A3054

Structurei

3D structure databases

ProteinModelPortaliQ467J7
SMRiQ467J7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the THEP1 NTPase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01034 Archaea
COG1618 LUCA
HOGENOMiHOG000006446
KOiK06928
OMAiVCIIDEI
OrthoDBiPOG093Z0D4B

Family and domain databases

HAMAPiMF_00796 NTPase_1, 1 hit
InterProiView protein in InterPro
IPR004948 Nuc-triphosphatase_THEP1
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF03266 NTPase_1, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

Sequencei

Sequence statusi: Complete.

Q467J7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRIAVTGIP GIGKSTVVAK AAEKLADQPG FKIGGIQTAE IRKEGQREGF
60 70 80 90 100
SIMDLATGKT GVLGSIRESG PRVGKYHVNL EDLEKIGANA LRSAMDCDLI
110 120 130 140 150
VIDEVGTMEL KSEAFVSAVK VVLESDKPVL AVLHRSSSHQ LVQRMRREFE
160 170
VLVVNEKNRD GLPGKIANRF REMR
Length:174
Mass (Da):18,995
Last modified:September 13, 2005 - v1
Checksum:iEF35886284D6AE7E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000099 Genomic DNA Translation: AAZ71945.1
RefSeqiWP_011307985.1, NC_007355.1

Genome annotation databases

EnsemblBacteriaiAAZ71945; AAZ71945; Mbar_A3054
GeneIDi3625065
KEGGimba:Mbar_A3054

Similar proteinsi

Entry informationi

Entry nameiNTPTH_METBF
AccessioniPrimary (citable) accession number: Q467J7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 13, 2005
Last modified: February 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health