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Protein

Uncharacterized lipoprotein YgeR

Gene

ygeR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Biological processi

  • autolysis Source: EcoliWiki
  • cell separation after cytokinesis Source: EcoliWiki

Enzyme and pathway databases

BioCyciEcoCyc:G7484-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized lipoprotein YgeR
Gene namesi
Name:ygeR
Ordered Locus Names:b2865, JW2833
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13048 ygeR

Subcellular locationi

  • Cell inner membrane Curated; Lipid-anchor PROSITE-ProRule annotation
  • Note: Slightly enriched at the septal ring.

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Cells are shorter in a single mutant, while triple envC-nlpD-ygeR disruptions have defects in septation and cell separation and form long filaments (15-fold longer) and further yet by the quadruple disruption mutant (envC-nlpD-mepM(yebA)-ygeR, over 21-fold longer). Quadruple mutants are less sensitive to ampicillin lysis.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25PROSITE-ProRule annotationAdd BLAST25
ChainiPRO_000001377626 – 251Uncharacterized lipoprotein YgeRAdd BLAST226

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi26N-palmitoyl cysteinePROSITE-ProRule annotation1
Lipidationi26S-diacylglycerol cysteinePROSITE-ProRule annotation1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiQ46798
PRIDEiQ46798

Interactioni

Protein-protein interaction databases

BioGridi4262318, 185 interactors
DIPiDIP-36034N
IntActiQ46798, 5 interactors
STRINGi316385.ECDH10B_3040

Structurei

3D structure databases

ProteinModelPortaliQ46798
SMRiQ46798
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 84LysMPROSITE-ProRule annotationAdd BLAST45

Sequence similaritiesi

Belongs to the peptidase M23B family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4108K5P Bacteria
COG0739 LUCA
HOGENOMiHOG000159026
InParanoidiQ46798
KOiK12943
OMAiPLRGYGN
PhylomeDBiQ46798

Family and domain databases

CDDicd00118 LysM, 1 hit
Gene3Di3.10.350.10, 1 hit
InterProiView protein in InterPro
IPR011055 Dup_hybrid_motif
IPR018392 LysM_dom
IPR036779 LysM_dom_sf
IPR016047 Peptidase_M23
PfamiView protein in Pfam
PF01476 LysM, 1 hit
PF01551 Peptidase_M23, 1 hit
SMARTiView protein in SMART
SM00257 LysM, 1 hit
SUPFAMiSSF51261 SSF51261, 1 hit
PROSITEiView protein in PROSITE
PS51782 LYSM, 1 hit
PS51257 PROKAR_LIPOPROTEIN, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q46798-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAGRLNKKS LGIVMLLSVG LLLAGCSGSK SSDTGTYSGS VYTVKRGDTL
60 70 80 90 100
YRISRTTGTS VKELARLNGI SPPYTIEVGQ KLKLGGAKSS SITRKSTAKS
110 120 130 140 150
TTKTASVTPS SAVPKSSWPP VGQRCWLWPT TGKVIMPYST ADGGNKGIDI
160 170 180 190 200
SAPRGTPIYA AGAGKVVYVG NQLRGYGNLI MIKHSEDYIT AYAHNDTMLV
210 220 230 240 250
NNGQSVKAGQ KIATMGSTDA ASVRLHFQIR YRATAIDPLR YLPPQGSKPK

C
Length:251
Mass (Da):26,565
Last modified:March 27, 2002 - v2
Checksum:iFCD6235D39790475
GO

Sequence cautioni

The sequence AAA83046 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28375 Genomic DNA Translation: AAA83046.1 Different initiation.
U00096 Genomic DNA Translation: AAC75903.2
AP009048 Genomic DNA Translation: BAE76931.1
PIRiA65070
RefSeqiNP_417341.4, NC_000913.3
WP_001301085.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75903; AAC75903; b2865
BAE76931; BAE76931; BAE76931
GeneIDi947352
KEGGiecj:JW2833
eco:b2865
PATRICifig|511145.12.peg.2958

Similar proteinsi

Entry informationi

Entry nameiYGER_ECOLI
AccessioniPrimary (citable) accession number: Q46798
Secondary accession number(s): Q2M9X5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: March 27, 2002
Last modified: March 28, 2018
This is version 132 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health