ID   Q46707_ECOLX            Unreviewed;       177 AA.
AC   Q46707;
DT   01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1996, sequence version 1.
DT   14-APR-2009, entry version 44.
DE   SubName: Full=Endonuclease;
DE   SubName: Full=Putative uncharacterized protein;
GN   Name=nuc; ORFNames=pMUR050_045;
OS   Escherichia coli.
OG   Plasmid pKM101, Plasmid pLEW517, and Plasmid pMUR050.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   PLASMID=pKM101;
RX   MEDLINE=94302136; PubMed=8029323; DOI=10.1006/plas.1994.1017;
RA   Pohlman R.F., Genetti H.D., Winans S.C.;
RT   "Entry exclusion of the IncN plasmid pKM101 is mediated by a single
RT   hydrophilic protein containing a lipid attachment motif.";
RL   Plasmid 31:158-165(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   PLASMID=pKM101;
RX   MEDLINE=95198540; PubMed=7891554;
RX   DOI=10.1111/j.1365-2958.1994.tb01304.x;
RA   Pohlman R.F., Genetti H.D., Winans S.C.;
RT   "Common ancestry between IncN conjugal transfer genes and
RT   macromolecular export systems of plant and animal pathogens.";
RL   Mol. Microbiol. 14:655-668(1994).
RN   [3]
RP   X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 23-177.
RC   PLASMID=pKM101;
RX   MEDLINE=99173242; PubMed=10074947; DOI=10.1038/6716;
RA   Stuckey J.A., Dixon J.E.;
RT   "Crystal structure of a phospholipase D family member.";
RL   Nat. Struct. Biol. 6:278-284(1999).
RN   [4]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=517-2H1; PLASMID=pLEW517;
RX   PubMed=16820486; DOI=10.1128/AEM.00354-06;
RA   Williams L.E., Detter C., Barry K., Lapidus A., Summers A.O.;
RT   "Facile recovery of individual high-molecular-weight, low-copy-number
RT   natural plasmids for genomic sequencing.";
RL   Appl. Environ. Microbiol. 72:4899-4906(2006).
RN   [5]
RP   NUCLEOTIDE SEQUENCE.
RC   PLASMID=pMUR050;
RX   PubMed=15963296;
RA   Gonzalez-Zorn B., Teshager T., Casas M., Porrero M.C., Moreno M.A.,
RA   Courvalin P., Dominguez L.;
RT   "armA and aminoglycoside resistance in Escherichia coli.";
RL   Emerg. Infect. Dis. 11:954-956(2005).
RN   [6]
RP   NUCLEOTIDE SEQUENCE.
RC   PLASMID=pMUR050;
RX   PubMed=16027145; DOI=10.1093/jac/dki246;
RA   Gonzalez-Zorn B., Catalan A., Escudero J.A., Dominguez L.,
RA   Teshager T., Porrero C., Moreno M.A.;
RT   "Genetic basis for dissemination of armA.";
RL   J. Antimicrob. Chemother. 56:583-585(2005).
RN   [7]
RP   NUCLEOTIDE SEQUENCE.
RC   PLASMID=pMUR050;
RA   Gonzalez-Zorn B., Catalan A., Moreno M.A., Dominguez L.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; U09868; AAA86461.1; -; Genomic_DNA.
DR   EMBL; AY522431; ABG33821.1; -; Genomic_DNA.
DR   EMBL; DQ390454; ABG49201.1; -; Genomic_DNA.
DR   PIR; I79276; I79276.
DR   RefSeq; YP_001096362.1; -.
DR   RefSeq; YP_001688182.1; -.
DR   RefSeq; YP_724502.1; -.
DR   PDB; 1BYR; X-ray; 2.00 A; A=23-177.
DR   PDB; 1BYS; X-ray; 2.00 A; A=23-177.
DR   PDBsum; 1BYR; -.
DR   PDBsum; 1BYS; -.
DR   GeneID; 3861224; -.
DR   GeneID; 4924687; -.
DR   GeneID; 5951202; -.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0008152; P:metabolic process; IEA:InterPro.
DR   InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR   SMART; SM00155; PLDc; 1.
DR   PROSITE; PS50035; PLD; 1.
PE   1: Evidence at protein level;
KW   Endonuclease; Hydrolase; Nuclease; Plasmid.
SQ   SEQUENCE   177 AA;  19445 MW;  E0EFD6133C328F3E CRC64;
     MKKLATWLLA AAFTTAALPA FAVEPSVQVG YSPEGSARVL VLSAIDSAKT SIRMMAYSFT
     APDIMKALVA AKKRGVDVKI VIDERGNTGR ASIAAMNYIA NSGIPLRTDS NFPIQHDKVI
     IVDNVTVETG SFNFTKAAET KNSENAVVIW NMPKLAESFL EHWQDRWNQG RDYRSSY
//