Q46707 (Q46707_ECOLX) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Endonuclease EMBL AAA86461.1

Gene names

Name:	nuc EMBL AAA86461.1
ORF Names:	pKC394-032 EMBL ADH29990.1, pKC396-025 EMBL ADH30040.1, pMUR050_045 EMBL ABG33821.1

Encoded on

Plasmid pKC396 Ref.3 Ref.8 EMBL ADH30040.1
Plasmid pLEW517 Ref.7 EMBL ABG49201.1
Plasmid pKC394 Ref.3 Ref.8 EMBL ADH29990.1
Plasmid pKM101 Ref.1 Ref.2 Ref.5 EMBL AAA86461.1
Plasmid pMUR050 Ref.4 Ref.6 Ref.9 EMBL ABG33821.1

Organism

Escherichia coli EMBL AAA86461.1

Taxonomic identifier

562 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	177 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Endonuclease EMBL AAA86461.1 Hydrolase Nuclease
Technical term	3D-structure PDB 1BYS PDB 1BYR Plasmid EMBL AAA86461.1
Gene Ontology (GO)
Molecular function	endonuclease activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q46707 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: E0EFD6133C328F3E	FASTA	177	19,445
	10 20 30 40 50 60 MKKLATWLLA AAFTTAALPA FAVEPSVQVG YSPEGSARVL VLSAIDSAKT SIRMMAYSFT 70 80 90 100 110 120 APDIMKALVA AKKRGVDVKI VIDERGNTGR ASIAAMNYIA NSGIPLRTDS NFPIQHDKVI 130 140 150 160 170 IVDNVTVETG SFNFTKAAET KNSENAVVIW NMPKLAESFL EHWQDRWNQG RDYRSSY

References

[1]	"Entry exclusion of the IncN plasmid pKM101 is mediated by a single hydrophilic protein containing a lipid attachment motif." Pohlman R.F., Genetti H.D., Winans S.C. Plasmid 31:158-165(1994) [PubMed: 8029323] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Common ancestry between IncN conjugal transfer genes and macromolecular export systems of plant and animal pathogens." Pohlman R.F., Genetti H.D., Winans S.C. Mol. Microbiol. 14:655-668(1994) [PubMed: 7891554] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	"A novel IS26 structure surrounds blaCTX-M genes in different plasmids from German clinical Escherichia coli isolates." Cullik A., Pfeifer Y., Prager R., von Baum H., Witte W. J. Med. Microbiol. 59:580-587(2010) [PubMed: 20093380] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: ST131 EMBL ADH29990.1.
[4]	"armA and aminoglycoside resistance in Escherichia coli." Gonzalez-Zorn B., Teshager T., Casas M., Porrero M.C., Moreno M.A., Courvalin P., Dominguez L. Emerg. Infect. Dis. 11:954-956(2005) [PubMed: 15963296] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[5]	"Crystal structure of a phospholipase D family member." Stuckey J.A., Dixon J.E. Nat. Struct. Biol. 6:278-284(1999) [PubMed: 10074947] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 23-177.
[6]	"Genetic basis for dissemination of armA." Gonzalez-Zorn B., Catalan A., Escudero J.A., Dominguez L., Teshager T., Porrero C., Moreno M.A. J. Antimicrob. Chemother. 56:583-585(2005) [PubMed: 16027145] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[7]	"Facile recovery of individual high-molecular-weight, low-copy-number natural plasmids for genomic sequencing." Williams L.E., Detter C., Barry K., Lapidus A., Summers A.O. Appl. Environ. Microbiol. 72:4899-4906(2006) [PubMed: 16820486] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 517-2H1 EMBL ABG49201.1.
[8]	"Complete nucleotide sequences of pKC394 and pKC396 harbouring multiple blaCTX M genes and their relationship to other IncN resistance plasmids." Cullik A., Witte W. Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: ST131 EMBL ADH29990.1.
[9]	Gonzalez-Zorn B., Catalan A., Moreno M.A., Dominguez L. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U09868 Genomic DNA. Translation: AAA86461.1.
AY522431 Genomic DNA. Translation: ABG33821.1.
DQ390454 Genomic DNA. Translation: ABG49201.1.
HM138652 Genomic DNA. Translation: ADH29990.1.
HM138653 Genomic DNA. Translation: ADH30040.1.

PIR

I79276.

RefSeq

YP_001096362.1. NC_009132.1.
YP_003717504.1. NC_014231.1.
YP_724502.1. NC_007682.3.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1BYR	X-ray	2.00	A	23-177	[»]
1BYS	X-ray	2.00	A	23-177	[»]

ProteinModelPortal

Q46707.

SMR

Q46707. Positions 24-175.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

3861224.
4924687.
9284748.

Phylogenomic databases

ProtClustDB

CLSK896431.

Family and domain databases

InterPro

IPR001736. PLipase_D/transphosphatidylase.
[Graphical view]

SMART

SM00155. PLDc. 1 hit.
[Graphical view]

PROSITE

PS50035. PLD. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q46707_ECOLX

Accession

Primary (citable) accession number: Q46707

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	October 19, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)