ID   AMSI_ERWAM              Reviewed;         144 AA.
AC   Q46630;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   16-JUN-2009, entry version 44.
DE   RecName: Full=Probable low molecular weight protein-tyrosine-phosphatase amsI;
DE            EC=3.1.3.48;
GN   Name=amsI;
OS   Erwinia amylovora (Fire blight bacteria).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Erwinia.
OX   NCBI_TaxID=552;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=EA1/79;
RX   MEDLINE=95319333; PubMed=7596293;
RX   DOI=10.1111/j.1365-2958.1995.tb02361.x;
RA   Bugert P., Geider K.;
RT   "Molecular analysis of the ams operon required for exopolysaccharide
RT   synthesis of Erwinia amylovora.";
RL   Mol. Microbiol. 15:917-933(1995).
CC   -!- FUNCTION: May function as a phosphatase required for amylovoran
CC       (an exopolysaccharide that functions as a virulence factor)
CC       production.
CC   -!- CATALYTIC ACTIVITY: Protein tyrosine phosphate + H(2)O = protein
CC       tyrosine + phosphate.
CC   -!- SIMILARITY: Belongs to the low molecular weight phosphotyrosine
CC       protein phosphatase family.
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DR   EMBL; X77921; CAA54881.1; -; Genomic_DNA.
DR   PIR; S61893; S52140.
DR   HSSP; P24666; 5PNT.
DR   BRENDA; 3.1.3.48; 81763.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
DR   GO; GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006470; P:protein amino acid dephosphorylation; IEA:InterPro.
DR   InterPro; IPR000106; Tyr_phospatase/Ars_reductase.
DR   InterPro; IPR017867; Tyr_phospatase_low_mol_wt.
DR   PANTHER; PTHR11717; Low_mwt_PTPase; 1.
DR   Pfam; PF01451; LMWPc; 1.
DR   PRINTS; PR00719; LMWPTPASE.
DR   SMART; SM00226; LMWPc; 1.
PE   3: Inferred from homology;
KW   Exopolysaccharide synthesis; Hydrolase; Protein phosphatase;
KW   Virulence.
FT   CHAIN         1    144       Probable low molecular weight protein-
FT                                tyrosine-phosphatase amsI.
FT                                /FTId=PRO_0000046578.
FT   ACT_SITE      9      9       Nucleophile (By similarity).
FT   ACT_SITE     14     14       By similarity.
FT   ACT_SITE    115    115       Proton donor (By similarity).
SQ   SEQUENCE   144 AA;  15772 MW;  85B64E5EBC52961F CRC64;
     MINSILVVCI GNICRSPTGE RLLKAALPER KIASAGLKAM VGGSADETAS IVANEHGVSL
     QDHVAQQLTA DMCRDSDLIL VMEKKHIDLV CRINPSVRGK TMLFGHWINQ QEIADPYKKS
     RDAFEAVYGV LENAAQKWVN ALSR
//