Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q46630 (AMSI_ERWAM) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable low molecular weight protein-tyrosine-phosphatase AmsI

EC=3.1.3.48
Gene names
Name:amsI
OrganismErwinia amylovora (Fire blight bacteria)
Taxonomic identifier552 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeErwinia

Protein attributes

Sequence length144 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

May function as a phosphatase required for amylovoran (an exopolysaccharide that functions as a virulence factor) production.

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sequence similarities

Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

Ontologies

Keywords
   Biological processExopolysaccharide synthesis
Virulence
   Molecular functionHydrolase
Protein phosphatase
Gene Ontology (GO)
   Biological_processpathogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

polysaccharide biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionprotein tyrosine phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 144144Probable low molecular weight protein-tyrosine-phosphatase AmsI
PRO_0000046578

Sites

Active site91Nucleophile By similarity
Active site141 By similarity
Active site1151Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q46630 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 85B64E5EBC52961F

FASTA14415,772
        10         20         30         40         50         60 
MINSILVVCI GNICRSPTGE RLLKAALPER KIASAGLKAM VGGSADETAS IVANEHGVSL 

        70         80         90        100        110        120 
QDHVAQQLTA DMCRDSDLIL VMEKKHIDLV CRINPSVRGK TMLFGHWINQ QEIADPYKKS 

       130        140 
RDAFEAVYGV LENAAQKWVN ALSR 

« Hide

References

[1]"Molecular analysis of the ams operon required for exopolysaccharide synthesis of Erwinia amylovora."
Bugert P., Geider K.
Mol. Microbiol. 15:917-933(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: EA1/79.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X77921 Genomic DNA. Translation: CAA54881.1.
PIRS52140. S61893.

3D structure databases

ProteinModelPortalQ46630.
SMRQ46630. Positions 1-144.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR023485. Ptyr_pPase_SF.
IPR000106. Tyr_phospatase/Ars_reductase.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view]
PANTHERPTHR11717. PTHR11717. 1 hit.
PfamPF01451. LMWPc. 1 hit.
[Graphical view]
PRINTSPR00719. LMWPTPASE.
SMARTSM00226. LMWPc. 1 hit.
[Graphical view]
SUPFAMSSF52788. SSF52788. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAMSI_ERWAM
AccessionPrimary (citable) accession number: Q46630
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: April 16, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families