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Protein

Probable low molecular weight protein-tyrosine-phosphatase AmsI

Gene

amsI

Organism
Erwinia amylovora (Fire blight bacteria)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

May function as a phosphatase required for amylovoran (an exopolysaccharide that functions as a virulence factor) production.

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei9NucleophileBy similarity1
Active sitei14By similarity1
Active sitei115Proton donorBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Biological processi

Exopolysaccharide synthesis, Virulence

Names & Taxonomyi

Protein namesi
Recommended name:
Probable low molecular weight protein-tyrosine-phosphatase AmsI (EC:3.1.3.48)
Gene namesi
Name:amsI
OrganismiErwinia amylovora (Fire blight bacteria)
Taxonomic identifieri552 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeErwinia

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000465781 – 144Probable low molecular weight protein-tyrosine-phosphatase AmsIAdd BLAST144

Interactioni

Protein-protein interaction databases

STRINGi665029.EAMY_2251.

Structurei

Secondary structure

1144
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi4 – 14Combined sources11
Helixi15 – 26Combined sources12
Beta strandi30 – 36Combined sources7
Helixi47 – 55Combined sources9
Helixi70 – 75Combined sources6
Beta strandi77 – 83Combined sources7
Helixi85 – 93Combined sources9
Helixi95 – 100Combined sources6
Beta strandi101 – 103Combined sources3
Helixi121 – 143Combined sources23

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4D74X-ray1.57A1-144[»]
ProteinModelPortaliQ46630.
SMRiQ46630.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4107ZF2. Bacteria.
COG0394. LUCA.

Family and domain databases

CDDicd00115. LMWPc. 1 hit.
InterProiIPR023485. Ptyr_pPase_SF.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view]
PANTHERiPTHR11717:SF20. PTHR11717:SF20. 1 hit.
PfamiPF01451. LMWPc. 1 hit.
[Graphical view]
PRINTSiPR00719. LMWPTPASE.
SMARTiSM00226. LMWPc. 1 hit.
[Graphical view]
SUPFAMiSSF52788. SSF52788. 1 hit.

Sequencei

Sequence statusi: Complete.

Q46630-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MINSILVVCI GNICRSPTGE RLLKAALPER KIASAGLKAM VGGSADETAS
60 70 80 90 100
IVANEHGVSL QDHVAQQLTA DMCRDSDLIL VMEKKHIDLV CRINPSVRGK
110 120 130 140
TMLFGHWINQ QEIADPYKKS RDAFEAVYGV LENAAQKWVN ALSR
Length:144
Mass (Da):15,772
Last modified:November 1, 1997 - v1
Checksum:i85B64E5EBC52961F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X77921 Genomic DNA. Translation: CAA54881.1.
PIRiS61893. S52140.

Genome annotation databases

GeneIDi8912405.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X77921 Genomic DNA. Translation: CAA54881.1.
PIRiS61893. S52140.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4D74X-ray1.57A1-144[»]
ProteinModelPortaliQ46630.
SMRiQ46630.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi665029.EAMY_2251.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8912405.

Phylogenomic databases

eggNOGiENOG4107ZF2. Bacteria.
COG0394. LUCA.

Family and domain databases

CDDicd00115. LMWPc. 1 hit.
InterProiIPR023485. Ptyr_pPase_SF.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view]
PANTHERiPTHR11717:SF20. PTHR11717:SF20. 1 hit.
PfamiPF01451. LMWPc. 1 hit.
[Graphical view]
PRINTSiPR00719. LMWPTPASE.
SMARTiSM00226. LMWPc. 1 hit.
[Graphical view]
SUPFAMiSSF52788. SSF52788. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiAMSI_ERWAM
AccessioniPrimary (citable) accession number: Q46630
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 2, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.