ID   PUR2_CHRVI              Reviewed;         189 AA.
AC   Q46482;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   16-JUN-2009, entry version 52.
DE   RecName: Full=Phosphoribosylamine--glycine ligase;
DE            EC=6.3.4.13;
DE   AltName: Full=GARS;
DE   AltName: Full=Glycinamide ribonucleotide synthetase;
DE   AltName: Full=Phosphoribosylglycinamide synthetase;
DE   Flags: Fragment;
GN   Name=purD;
OS   Chromatium vinosum (Allochromatium vinosum).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales;
OC   Chromatiaceae; Allochromatium.
OX   NCBI_TaxID=1049;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 17899 / DSM 180 / D;
RA   Chen Y.L., Knaff D.B.;
RL   Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: ATP + 5-phospho-D-ribosylamine + glycine = ADP
CC       + phosphate + N(1)-(5-phospho-D-ribosyl)glycinamide.
CC   -!- PATHWAY: Purine metabolism; IMP biosynthesis via de novo pathway;
CC       N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-
CC       ribose 1-diphosphate: step 2/2.
CC   -!- SIMILARITY: Belongs to the GARS family.
CC   -!- SIMILARITY: Contains 1 ATP-grasp domain.
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DR   EMBL; L76417; AAB02980.1; -; Genomic_DNA.
DR   HSSP; P15640; 1GSO.
DR   BRENDA; 6.3.4.13; 2799.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:HAMAP.
DR   GO; GO:0009113; P:purine base biosynthetic process; IEA:InterPro.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00138; -; 1.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR000115; Gars.
DR   InterPro; IPR013817; Pre-ATP_grasp.
DR   Gene3D; G3DSA:3.30.1490.20; ATP_grasp_subdomain_1; 1.
DR   Gene3D; G3DSA:3.40.50.20; Pre-ATP_grasp; 1.
DR   Pfam; PF01071; GARS_A; 1.
DR   Pfam; PF02844; GARS_N; 1.
DR   PROSITE; PS50975; ATP_GRASP; 1.
DR   PROSITE; PS00184; GARS; PARTIAL.
PE   3: Inferred from homology;
KW   ATP-binding; Ligase; Nucleotide-binding; Purine biosynthesis.
FT   CHAIN         1   >189       Phosphoribosylamine--glycine ligase.
FT                                /FTId=PRO_0000151443.
FT   DOMAIN      109   >189       ATP-grasp.
FT   NP_BIND     135    159       ATP (By similarity).
FT   NON_TER     189    189
SQ   SEQUENCE   189 AA;  18912 MW;  C9F39F5EEE4A6BEC CRC64;
     MKILIVGSGG REHALAWKAA QSPQVEQVFV APGNGGTASE PGVENVAIAA DDIAGLVEFA
     RRESIGLTIV GPEAPLVLGL VDAFAEAGLP CFGPASGSAQ LEGSKAFAKD FLHRHGIPTA
     AYGVFTELEP ALAYLRQVGA PVVVKADGLA AGKGVILAMI LATAGGGVHD MLGADAFGPG
     GGGVVIEEF
//