Reviewed, UniProtKB/Swiss-Prot Q46338 (SOXG_CORS1)

Names and origin

Protein names

Recommended name:
    Sarcosine oxidase subunit gamma
    EC=1.5.3.1

Gene names

Name:

soxG

Organism

Corynebacterium sp. (strain P-1)

Taxonomic identifier

69006 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	203 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

General annotation (Comments)

Function	Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10-methylenetetrahydrofolate.
Catalytic activity	Sarcosine + H(2)O + O(2) = glycine + formaldehyde + H(2)O(2).
Subunit structure	Heterotetramer (alpha 100 kDa, beta 42 kDa, gamma 20 kDa, and delta 6 kDa).
Subcellular location	Cytoplasm.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	sarcosine oxidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 203	203	Sarcosine oxidase subunit gamma		PRO_0000072051

Sequences

	Sequence		Length	Mass (Da)
	Q46338-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 5A362FABFBCAED7F	FASTA	203	21,030
	10 20 30 40 50 60 MASNTLIEST SVRRSPAEHL AEAMAQGSTA GTVQLREIAF ATQVGVRAVP GSGGFAALAE 70 80 90 100 110 120 AVGTGLPQQV GVVAGSVEGT AVLWLGPDEF LAIAPEGAEL AAELVAALGD EPGQVLDLSA 130 140 150 160 170 180 NRSVLELSGP AAPLVLRKSC PADLHPRAFG VNLAITTTLA NIPVLLWRTG EQSWYILPRA 190 200 SFTEHTVHWL IDAMSEFASE PVA

References

[1]	"Sequence analysis of sarcosine oxidase and nearby genes reveals homologies with key enzymes of folate one-carbon metabolism." Chlumsky L.J., Zhang L., Jorns M.S. J. Biol. Chem. 270:18252-18259(1995) [PubMed: 7543100] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	U23955 Genomic DNA. Translation: AAC43462.1.
3D structure databases
SMR	Q46338. Positions 10-199.
ModBase	Search...
Enzyme and pathway databases
BioCyc	MetaCyc:MON-8523.
Family and domain databases
InterPro	IPR007375. SoxG. IPR006280. SoxG_het. [Graphical view]
Pfam	PF04268. SoxG. 1 hit. [Graphical view]
TIGRFAMs	TIGR01375. soxG. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SOXG_CORS1

Accession

Primary (citable) accession number: Q46338

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	November 4, 2008
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)