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Protein
Submitted name:

Iota toxin component Ib

Gene
N/A
Organism
Clostridium perfringens
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

Complete GO annotation...

Protein family/group databases

TCDBi1.C.42.1.3. the channel-forming bacillus anthracis protective antigen (bapa) family.

Names & Taxonomyi

Protein namesi
Submitted name:
Iota toxin component IbImported
OrganismiClostridium perfringensImported
Taxonomic identifieri1502 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2828Sequence analysisAdd
BLAST
Chaini29 – 875847Sequence analysisPRO_5004232314Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ46221.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini49 – 182134PA14InterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di2.60.120.240. 1 hit.
3.10.20.110. 1 hit.
3.90.182.10. 1 hit.
InterProiIPR003896. Bacterial_exotoxin_B.
IPR023125. Bacterial_exotoxin_B_Fd-like.
IPR011658. PA14_dom.
IPR027439. PA_heptamer_dom.
[Graphical view]
PfamiPF03495. Binary_toxB. 1 hit.
[Graphical view]
PRINTSiPR01391. BINARYTOXINB.
SMARTiSM00758. PA14. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q46221-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIQIKNVFS FLTLTAMISQ TLSYNVYAQT TTQNDTNQKE EITNENTLSS
60 70 80 90 100
NGLMGYYFAD EHFKDLELMA PIKNGDLKFE EKKVDKLLTE DNSSIKSIRW
110 120 130 140 150
TGRIIPSEDG EYILSTDRND VLMQINAKGD IAKTLKVNMK KGQAYNIRIE
160 170 180 190 200
IQDKNLGSID NLSVPKLYWE LNGNKTVIPE ENLFFRDYSK IDENDPFIPN
210 220 230 240 250
NNFFDVRFFS AAWEDEDLDT DNDNIPDAYE KNGYTIKDSI AVKWNDSFAE
260 270 280 290 300
QGYKKYVSSY LESNTAGDPY TDYQKASGSI DKAIKLEARD PLVAAYPVVG
310 320 330 340 350
VGMENLIIST NEHASSDQGK TVSRATTNSK TDANTVGVSI SAGYQNGFTG
360 370 380 390 400
NITTSYSHTT DNSTAVQDSN GESWNTGLSI NKGESAYINA NVRYYNTGTA
410 420 430 440 450
PMYKVTPTTN LVLDGETLAT IKAQDNQIGN NLSPNETYPK KGLSPLALNT
460 470 480 490 500
MDQFNARLIP INYDQLKKLD SGKQIKLETT QVSGNYGTKN SQGQIITEGN
510 520 530 540 550
SWSNYISQID SVSASIILDT GSQTFERRVA AKEQGNPEDK TPEITIGEAI
560 570 580 590 600
KKAFSATKNG ELLYFNGIPI DESCVELIFD DNTSEIIKEQ LKYLDDKKIY
610 620 630 640 650
NVKLERGMNI LIKVPSYFTN FDEYNNFPAS WSNIDTKNQD GLQSVANKLS
660 670 680 690 700
GETKIIIPMS KLKPYKRYVF SGYSKDPSTS NSITVNIKSK EQKTDYLVPE
710 720 730 740 750
KDYTKFSYEF ETTGKDSSDI EITLTSSGVI FLDNLSITEL NSTPEILKEP
760 770 780 790 800
EIKVPSDQEI LDAHNKYYAD IKLDTNTGNT YIDGIYFEPT QTNKEALDYI
810 820 830 840 850
QKYRVEATLQ YSGFKDIGTK DKEIRNYLGD QNQPKTNYIN FRSYFTSGEN
860 870
VMTYKKLRIY AVTPDNRELL VLSVN
Length:875
Mass (Da):98,469
Last modified:November 1, 1996 - v1
Checksum:iC9AE092CD3818921
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73562 Genomic DNA. Translation: CAA51960.1.
PIRiI40862.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73562 Genomic DNA. Translation: CAA51960.1.
PIRiI40862.

3D structure databases

ProteinModelPortaliQ46221.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

TCDBi1.C.42.1.3. the channel-forming bacillus anthracis protective antigen (bapa) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.60.120.240. 1 hit.
3.10.20.110. 1 hit.
3.90.182.10. 1 hit.
InterProiIPR003896. Bacterial_exotoxin_B.
IPR023125. Bacterial_exotoxin_B_Fd-like.
IPR011658. PA14_dom.
IPR027439. PA_heptamer_dom.
[Graphical view]
PfamiPF03495. Binary_toxB. 1 hit.
[Graphical view]
PRINTSiPR01391. BINARYTOXINB.
SMARTiSM00758. PA14. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Characterization of Clostridium perfringens iota-toxin genes and expression in Escherichia coli."
    Perelle S., Gibert M., Boquet P., Popoff M.R.
    Infect. Immun. 61:5147-5156(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NCIB 10748Imported.
  2. Popoff M.R.
    Submitted (AUG-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NCIB 10748Imported.

Entry informationi

Entry nameiQ46221_CLOPF
AccessioniPrimary (citable) accession number: Q46221
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: December 9, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.