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Protein

Anaerobic regulatory protein

Gene

fnr

Organism
Capnocytophaga sputigena
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

It is involved in the activation of genes necessary for anaerobic respiration.

Cofactori

[4Fe-4S] clusterBy similarityNote: Binds 1 [4Fe-4S] cluster per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi1 – 11Iron-sulfur (4Fe-4S)Sequence Analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

4Fe-4S, DNA-binding, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Anaerobic regulatory protein
Gene namesi
Name:fnr
OrganismiCapnocytophaga sputigena
Taxonomic identifieri1019 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeCapnocytophaga

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – ›92›92Anaerobic regulatory proteinPRO_0000100175Add
BLAST

Expressioni

Inductioni

By anaerobiosis.

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ46159.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini43 – ›92›50HTH crp-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH crp-type DNA-binding domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProiIPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00325. Crp. 1 hit.
[Graphical view]
PRINTSiPR00034. HTHCRP.
PROSITEiPS51063. HTH_CRP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q46159-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
CEIPFETLDD LSGKMPNLRQ QMMRLMSGEI KGDQDMILLL SKKNAEERLD
60 70 80 90
VFIYNLSRRF GQRGFSPREF RLTMTRGDIG NYLGLTVETI SR
Length:92
Mass (Da):10,690
Last modified:November 1, 1996 - v1
Checksum:i813866DA55FFB74E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11
Non-terminal residuei92 – 921

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D78253 Genomic DNA. Translation: BAA11317.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D78253 Genomic DNA. Translation: BAA11317.1.

3D structure databases

ProteinModelPortaliQ46159.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProiIPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00325. Crp. 1 hit.
[Graphical view]
PRINTSiPR00034. HTHCRP.
PROSITEiPS51063. HTH_CRP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Novel FNR homologues identified in four representative oral facultative anaerobes: Capnocytophaga ochracea, Capnocytophaga sputigena, Haemophilus aphrophilus, and Actinobacillus actinomycetemcomitans."
    Hattori T., Takahashi K., Nakanishi T., Ohta H., Fukui K., Taniguchi S., Takigawa M.
    FEMS Microbiol. Lett. 137:213-220(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 33612 / DSM 7273 / JCM 12967.

Entry informationi

Entry nameiFNR_CAPSP
AccessioniPrimary (citable) accession number: Q46159
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2002
Last sequence update: November 1, 1996
Last modified: January 7, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.