Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Bacterial non-heme ferritin

Gene

ftn

Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Iron-storage protein.

Catalytic activityi

4 Fe2+ + O2 + 6 H2O = 4 (FeO(OH)) + 8 H+.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi17Iron 1PROSITE-ProRule annotation1
Metal bindingi50Iron 1PROSITE-ProRule annotation1
Metal bindingi50Iron 2PROSITE-ProRule annotation1
Metal bindingi53Iron 1PROSITE-ProRule annotation1
Metal bindingi94Iron 2PROSITE-ProRule annotation1
Metal bindingi127Iron 2PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Iron storage

Keywords - Ligandi

Iron, Metal-binding

Enzyme and pathway databases

BioCyciCJEJ192222:GJTS-579-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Bacterial non-heme ferritin (EC:1.16.3.2)
Gene namesi
Name:ftn
Synonyms:cft
Ordered Locus Names:Cj0612c
OrganismiCampylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Taxonomic identifieri192222 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000000799 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002010951 – 167Bacterial non-heme ferritinAdd BLAST167

Proteomic databases

PaxDbiQ46106.
PRIDEiQ46106.

Interactioni

Subunit structurei

Homooligomer of 24 subunits that assemble into a spherical protein shell (12 +/- 1 nM diameter) that can sequester at least 2000 iron atoms.By similarity

Protein-protein interaction databases

STRINGi192222.Cj0612c.

Structurei

Secondary structure

1167
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi4 – 33Combined sources30
Helixi37 – 62Combined sources26
Turni63 – 65Combined sources3
Helixi83 – 110Combined sources28
Helixi114 – 119Combined sources6
Helixi121 – 144Combined sources24
Turni147 – 149Combined sources3
Helixi150 – 163Combined sources14

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1KRQX-ray2.70A1-167[»]
ProteinModelPortaliQ46106.
SMRiQ46106.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ46106.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 145Ferritin-like diironPROSITE-ProRule annotationAdd BLAST145

Sequence similaritiesi

Belongs to the ferritin family. Prokaryotic subfamily.Curated
Contains 1 ferritin-like diiron domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG41090A1. Bacteria.
COG1528. LUCA.
HOGENOMiHOG000223382.
KOiK02217.
OMAiCEDKGFE.

Family and domain databases

Gene3Di1.20.1260.10. 1 hit.
InterProiIPR001519. Ferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR008331. Ferritin_DPS_dom.
[Graphical view]
PANTHERiPTHR11431. PTHR11431. 1 hit.
PfamiPF00210. Ferritin. 1 hit.
[Graphical view]
SUPFAMiSSF47240. SSF47240. 1 hit.
PROSITEiPS50905. FERRITIN_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q46106-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSKEVVKLL NEQINKEMYA ANLYLSMSSW CYENSLDGAG AFLFAHASEE
60 70 80 90 100
SDHAKKLITY LNETDSHVEL QEVKQPEQNF KSLLDVFEKT YEHEQFITKS
110 120 130 140 150
INTLVEHMLT HKDYSTFNFL QWYVSEQHEE EALFRGIVDK IKLIGEHGNG
160
LYLADQYIKN IALSRKK
Length:167
Mass (Da):19,486
Last modified:November 1, 1996 - v1
Checksum:iB2CFB612DAD0D9DA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D64082 Genomic DNA. Translation: BAA10964.1.
AL111168 Genomic DNA. Translation: CAL34758.1.
PIRiS77578.
RefSeqiWP_002852256.1. NC_002163.1.
YP_002344042.1. NC_002163.1.

Genome annotation databases

EnsemblBacteriaiCAL34758; CAL34758; Cj0612c.
GeneIDi904939.
KEGGicje:Cj0612c.
PATRICi20058168. VBICamJej33762_0604.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D64082 Genomic DNA. Translation: BAA10964.1.
AL111168 Genomic DNA. Translation: CAL34758.1.
PIRiS77578.
RefSeqiWP_002852256.1. NC_002163.1.
YP_002344042.1. NC_002163.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1KRQX-ray2.70A1-167[»]
ProteinModelPortaliQ46106.
SMRiQ46106.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi192222.Cj0612c.

Proteomic databases

PaxDbiQ46106.
PRIDEiQ46106.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL34758; CAL34758; Cj0612c.
GeneIDi904939.
KEGGicje:Cj0612c.
PATRICi20058168. VBICamJej33762_0604.

Phylogenomic databases

eggNOGiENOG41090A1. Bacteria.
COG1528. LUCA.
HOGENOMiHOG000223382.
KOiK02217.
OMAiCEDKGFE.

Enzyme and pathway databases

BioCyciCJEJ192222:GJTS-579-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ46106.

Family and domain databases

Gene3Di1.20.1260.10. 1 hit.
InterProiIPR001519. Ferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR008331. Ferritin_DPS_dom.
[Graphical view]
PANTHERiPTHR11431. PTHR11431. 1 hit.
PfamiPF00210. Ferritin. 1 hit.
[Graphical view]
SUPFAMiSSF47240. SSF47240. 1 hit.
PROSITEiPS50905. FERRITIN_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFTN_CAMJE
AccessioniPrimary (citable) accession number: Q46106
Secondary accession number(s): Q0PAQ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.