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Protein
Submitted name:

ColH protein

Gene

colH

Organism
Hathewaya histolytica (Clostridium histolyticum)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi421ZincCombined sources1
Metal bindingi455Zinc; via tele nitrogenCombined sources1
Metal bindingi459Zinc; via tele nitrogenCombined sources1
Metal bindingi463Calcium 1; via carbonyl oxygenCombined sources1
Metal bindingi467Calcium 1; via carbonyl oxygenCombined sources1
Metal bindingi469Calcium 1; via carbonyl oxygenCombined sources1
Metal bindingi487ZincCombined sources1
Metal bindingi725Calcium 2Combined sources1
Metal bindingi726Calcium 2; via carbonyl oxygenCombined sources1
Metal bindingi753Calcium 2Combined sources1
Metal bindingi755Calcium 2Combined sources1
Metal bindingi794Calcium 2Combined sources1
Metal bindingi814Calcium 3Combined sources1
Metal bindingi815Calcium 3; via carbonyl oxygenCombined sources1
Metal bindingi842Calcium 3Combined sources1
Metal bindingi844Calcium 3Combined sources1
Metal bindingi884Calcium 3Combined sources1
Metal bindingi908Calcium 4Combined sources1
Metal bindingi910Calcium 4Combined sources1
Metal bindingi910Calcium 5Combined sources1
Metal bindingi912Calcium 5Combined sources1
Metal bindingi913Calcium 5Combined sources1
Metal bindingi931Calcium 4; via carbonyl oxygenCombined sources1
Metal bindingi937Calcium 4Combined sources1
Metal bindingi937Calcium 5Combined sources1
Metal bindingi938Calcium 5; via carbonyl oxygenCombined sources1
Metal bindingi939Calcium 4Combined sources1
Metal bindingi939Calcium 5Combined sources1

GO - Molecular functioni

Keywordsi

LigandCalciumCombined sources, Metal-bindingCombined sources, ZincCombined sources

Protein family/group databases

MEROPSiM09.003.

Names & Taxonomyi

Protein namesi
Submitted name:
ColH proteinImported
Submitted name:
CollagenaseImported
Gene namesi
Name:colHImported
OrganismiHathewaya histolytica (Clostridium histolyticum)Imported
Taxonomic identifieri1498 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeHathewaya

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_501084360531 – 1021Sequence analysisAdd BLAST991

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3JQWX-ray2.00A/B/C902-1021[»]
3JQXX-ray2.20A/B/C902-1021[»]
4AR1X-ray2.01A331-721[»]
4ARFX-ray1.77A331-721[»]
4JGUX-ray1.42A/B806-900[»]
4U6TX-ray1.76A/B/C/D725-810[»]
4U7KX-ray1.91A/B/C/D/E/F/G/H724-810[»]
SMRiQ46085.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini727 – 808PKDInterPro annotationAdd BLAST82
Domaini816 – 905PKDInterPro annotationAdd BLAST90

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR013320. ConA-like_dom_sf.
IPR013783. Ig-like_fold.
IPR013661. Peptidase_M9_N_dom.
IPR002169. Peptidase_M9A/M9B.
IPR022409. PKD/Chitinase_dom.
IPR000601. PKD_dom.
IPR035986. PKD_dom_sf.
PfamiView protein in Pfam
PF01752. Peptidase_M9. 1 hit.
PF08453. Peptidase_M9_N. 1 hit.
PF00801. PKD. 2 hits.
PRINTSiPR00931. MICOLLPTASE.
SMARTiView protein in SMART
SM00089. PKD. 2 hits.
SUPFAMiSSF49299. SSF49299. 2 hits.
SSF49899. SSF49899. 1 hit.
PROSITEiView protein in PROSITE
PS50093. PKD. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q46085-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRKCLSKRL MLAITMATIF TVNSTLPIYA AVDKNNATAA VQNESKRYTV
60 70 80 90 100
SYLKTLNYYD LVDLLVKTEI ENLPDLFQYS SDAKEFYGNK TRMSFIMDEI
110 120 130 140 150
GRRAPQYTEI DHKGIPTLVE VVRAGFYLGF HNKELNEINK RSFKERVIPS
160 170 180 190 200
ILAIQKNPNF KLGTEVQDKI VSATGLLAGN ETAPPEVVNN FTPILQDCIK
210 220 230 240 250
NIDRYALDDL KSKALFNVLA APTYDITEYL RATKEKPENT PWYGKIDGFI
260 270 280 290 300
NELKKLALYG KINDNNSWII DNGIYHIAPL GKLHSNNKIG IETLTEVMKV
310 320 330 340 350
YPYLSMQHLQ SADQIKRHYD SKDAEGNKIP LDKFKKEGKE KYCPKTYTFD
360 370 380 390 400
DGKVIIKAGA RVEEEKVKRL YWASKEVNSQ FFRVYGIDKP LEEGNPDDIL
410 420 430 440 450
TMVIYNSPEE YKLNSVLYGY DTNNGGMYIE PEGTFFTYER EAQESTYTLE
460 470 480 490 500
ELFRHEYTHY LQGRYAVPGQ WGRTKLYDND RLTWYEEGGA ELFAGSTRTS
510 520 530 540 550
GILPRKSIVS NIHNTTRNNR YKLSDTVHSK YGASFEFYNY ACMFMDYMYN
560 570 580 590 600
KDMGILNKLN DLAKNNDVDG YDNYIRDLSS NYALNDKYQD HMQERIDNYE
610 620 630 640 650
NLTVPFVADD YLVRHAYKNP NEIYSEISEV AKLKDAKSEV KKSQYFSTFT
660 670 680 690 700
LRGSYTGGAS KGKLEDQKAM NKFIDDSLKK LDTYSWSGYK TLTAYFTNYK
710 720 730 740 750
VDSSNRVTYD VVFHGYLPNE GDSKNSLPYG KINGTYKGTE KEKIKFSSEG
760 770 780 790 800
SFDPDGKIVS YEWDFGDGNK SNEENPEHSY DKVGTYTVKL KVTDDKGESS
810 820 830 840 850
VSTTTAEIKD LSENKLPVIY MHVPKSGALN QKVVFYGKGT YDPDGSIAGY
860 870 880 890 900
QWDFGDGSDF SSEQNPSHVY TKKGEYTVTL RVMDSSGQMS EKTMKIKITD
910 920 930 940 950
PVYPIGTEKE PNNSKETASG PIVPGIPVSG TIENTSDQDY FYFDVITPGE
960 970 980 990 1000
VKIDINKLGY GGATWVVYDE NNNAVSYATD DGQNLSGKFK ADKPGRYYIH
1010 1020
LYMFNGSYMP YRINIEGSVG R
Length:1,021
Mass (Da):116,377
Last modified:November 1, 1996 - v1
Checksum:i826F45EFD96F917C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D29981 Genomic DNA. Translation: BAA06251.1.
AB014075 Genomic DNA. Translation: BAA34542.1.
PIRiI40805.

Entry informationi

Entry nameiQ46085_HATHI
AccessioniPrimary (citable) accession number: Q46085
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 22, 2017
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources