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Q45UF6

- NSP1N_ROTJ1

UniProt

Q45UF6 - NSP1N_ROTJ1

Protein

Non-structural protein 1

Gene
N/A
Organism
Rotavirus B (isolate Human/China/ADRV-N J19/1997) (RV ADRV-N) (Rotavirus (isolate novel adult diarrhea rotavirus-J19))
Status
Reviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 31 (01 Oct 2014)
      Sequence version 1 (13 Sep 2005)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei326 – 3272Cleavage; by autolysisSequence Analysis

    GO - Molecular functioni

    1. RNA binding Source: UniProtKB-KW

    Keywords - Ligandi

    RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Non-structural protein 1
    Short name:
    NSP1
    OrganismiRotavirus B (isolate Human/China/ADRV-N J19/1997) (RV ADRV-N) (Rotavirus (isolate novel adult diarrhea rotavirus-J19))
    Taxonomic identifieri335103 [NCBI]
    Taxonomic lineageiVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirusunclassified rotaviruses
    Virus hostiHomo sapiens (Human) [TaxID: 9606]
    ProteomesiUP000007663: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 395395Non-structural protein 1PRO_0000369859Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ45UF6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini328 – 39568DRBMPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 DRBM (double-stranded RNA-binding) domain.PROSITE-ProRule annotation

    Family and domain databases

    Gene3Di3.30.160.20. 1 hit.
    InterProiIPR014720. dsRNA-bd_dom.
    [Graphical view]
    PfamiPF00035. dsrm. 1 hit.
    [Graphical view]
    SMARTiSM00358. DSRM. 1 hit.
    [Graphical view]
    PROSITEiPS50137. DS_RBD. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q45UF6-1 [UniParc]FASTAAdd to Basket

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    MMSIQRAAQI NRQFDYMSIK ELWMAKFPLH KPGDCLDMFK NGDYTGPTMG    50
    CIQKTKASKK NTIFHIKSDF NSTEYDEPPI SGFKMFTQHC CQRIDEHFCG 100
    ALHPVISNIE FEHNQLKTRP QVASELNLFI PCGIKNLKIE SGEKSTWIVG 150
    TKFRKCMCLK PVIVAATIIG TPINKNLITF CSSDYIQVIV NRNREGSCGI 200
    CMGNVSTYEA CGNWTNETWG EEFSLDLKLC YKCTPVAFIF SLMMSTGHKP 250
    YVSKKQFEEN RRKWERVLNY KICKENLDSH LACANHENVY KSIKKYEFFD 300
    SVWVYHLANS SWVRDLTREC IESNPGPNYI QLLNEHSQRY GFVQPTYEII 350
    AVVSDGHHSY QCTCYYKDMK TQSTGPSKKN AKHQAAEQMF RHQCF 395
    Length:395
    Mass (Da):45,649
    Last modified:September 13, 2005 - v1
    Checksum:i19D9915601794AB4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY632079 Genomic RNA. Translation: AAU88188.1.
    DQ113901 Genomic RNA. Translation: AAZ03489.1.
    RefSeqiYP_392494.1. NC_007552.1.

    Genome annotation databases

    GeneIDi5076654.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY632079 Genomic RNA. Translation: AAU88188.1 .
    DQ113901 Genomic RNA. Translation: AAZ03489.1 .
    RefSeqi YP_392494.1. NC_007552.1.

    3D structure databases

    ProteinModelPortali Q45UF6.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 5076654.

    Family and domain databases

    Gene3Di 3.30.160.20. 1 hit.
    InterProi IPR014720. dsRNA-bd_dom.
    [Graphical view ]
    Pfami PF00035. dsrm. 1 hit.
    [Graphical view ]
    SMARTi SM00358. DSRM. 1 hit.
    [Graphical view ]
    PROSITEi PS50137. DS_RBD. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and sequence analysis of dsRNA segments 5, 6 and 7 of a novel non-group A, B, C adult rotavirus that caused an outbreak of gastroenteritis in China."
      Yang H., Makeyev E.V., Kang Z., Ji S., Bamford D.H., van Dijk A.A.
      Virus Res. 106:15-26(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
    2. "Molecular characterization of a novel adult diarrhoea rotavirus strain J19 isolated in China and its significance for the evolution and origin of group B rotaviruses."
      Jiang S., Ji S., Tang Q., Cui X., Yang H., Kan B., Gao S.
      J. Gen. Virol. 89:2622-2629(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

    Entry informationi

    Entry nameiNSP1N_ROTJ1
    AccessioniPrimary (citable) accession number: Q45UF6
    Secondary accession number(s): Q5Y9B1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: September 13, 2005
    Last modified: October 1, 2014
    This is version 31 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3