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Q45UF0 (NSP5_ROTJ1) Reviewed, UniProtKB/Swiss-Prot

Last modified September 18, 2013. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length176 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in genome replication. Plays a crucial role, together with NSP2, in the formation of virus factories (viroplasms) which are large inclusions in the cytoplasm where core-like replication intermediates are assembled and RNA replication takes place By similarity.

Subunit structure

Homodimer. Interacts with VP1. Interacts with VP2. Interacts with NSP2; this interaction leads to formation of virus factories By similarity.

Subcellular location

Host cytoplasm. Note: Found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging By similarity.

Sequence similarities

Belongs to the rotavirus B NSP5 family.

Ontologies

Keywords
   Cellular componentHost cytoplasm
   DomainCoiled coil
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componenthost cell cytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 176176Non-structural protein 5
PRO_0000369868

Regions

Coiled coil105 – 13935 Potential

Sequences

Sequence LengthMass (Da)Tools
Q45UF0 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: CE5DBF0DD89BCE74

FASTA17620,138
        10         20         30         40         50         60 
MSEVPRFELR SKRKIGKKQK VDIFGDKDDE SMLQIDCETD SLISESVSST HSYEDYSKAY 

        70         80         90        100        110        120 
KELTLETPAD VNDSASTIVD SVCEESWYDK TIKDEQTKED KKTDKKLKRI EKVKENNQND 

       130        140        150        160        170 
SMSLQIAQLS LRIQRIESET KLKTLDSAYN TIITQADNLT TPQKKSLISA ILATMR 

« Hide

References

[1]"Molecular characterization of a novel adult diarrhoea rotavirus strain J19 isolated in China and its significance for the evolution and origin of group B rotaviruses."
Jiang S., Ji S., Tang Q., Cui X., Yang H., Kan B., Gao S.
J. Gen. Virol. 89:2622-2629(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ113907 Genomic RNA. Translation: AAZ03495.1.
RefSeqYP_392500.1. NC_007558.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5076660.

Family and domain databases

InterProIPR020244. Rotavirus_B_NSP5.
[Graphical view]
ProDomPD035122. Rotavirus_B_NSP5. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameNSP5_ROTJ1
AccessionPrimary (citable) accession number: Q45UF0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 13, 2005
Last modified: September 18, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families