Q45QX2 (Q45QX2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Tumor necrosis factor ligand superfamily member 5 EMBL AAZ23548.1

Gene names

Name:

CD40LG EMBL AAZ23548.1

Organism

Homo sapiens (Human) EMBL AAZ23548.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	124 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Cytokine SAAS SAAS006052
Gene Ontology (GO)
Biological_process	immune response Inferred from electronic annotation. Source: InterPro
Cellular_component	extracellular space Inferred from electronic annotation. Source: UniProtKB-KW membrane Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAZ23548.1

Sequences

	Sequence		Length	Mass (Da)
	Q45QX2 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: F14E624BE85835BB	FASTA	124	13,617
	10 20 30 40 50 60 LQWAEKGYYT MSNNLVTLEN GKQLTVKRQV LYYIYAQVTF CSNREASSQA PFIASLCLKS 70 80 90 100 110 120 PGRFERILLR AANTHSSAKP CGQQSIHLGG VFELQPGASV FVNVTDPSQV SHGTGFTSFG LLKL

References

[1]	"Novel CD40 ligand mutation in a patient suffering from hyper-IgM syndrome." Schleithoff L., Schlueter G., Seelig H.P. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 05164943 EMBL AAZ23548.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DQ119668 Genomic DNA. Translation: AAZ23548.1.
IPI	IPI00643618.
UniGene	Hs.592244.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q45QX2.
Proteomic databases
PRIDE	Q45QX2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG079629.
Gene expression databases
ArrayExpress	Q45QX2.
Family and domain databases
Gene3D	2.60.120.40. 1 hit.
InterPro	IPR006052. TNF. IPR003263. TNF_ligand_5. IPR008983. Tumour_necrosis_fac-like_dom. [Graphical view]
Pfam	PF00229. TNF. 1 hit. [Graphical view]
PRINTS	PR01702. CD40LIGAND.
SMART	SM00207. TNF. 1 hit. [Graphical view]
SUPFAM	SSF49842. TNF_like. 1 hit.
PROSITE	PS50049. TNF_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q45QX2_HUMAN

Accession

Primary (citable) accession number: Q45QX2

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	March 6, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.