ID   Q45G71_RAT              Unreviewed;       290 AA.
AC   Q45G71;
DT   13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2005, sequence version 1.
DT   27-MAR-2024, entry version 130.
DE   RecName: Full=arylamine N-acetyltransferase {ECO:0000256|ARBA:ARBA00012701};
DE            EC=2.3.1.5 {ECO:0000256|ARBA:ARBA00012701};
GN   Name=Nat1 {ECO:0000313|EMBL:AAZ53275.1, ECO:0000313|RGD:70490};
GN   Synonyms=Nat2 {ECO:0000313|RGD:70490};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116 {ECO:0000313|EMBL:AAZ53275.1};
RN   [1] {ECO:0000313|EMBL:AAZ53275.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ACI {ECO:0000313|EMBL:AAZ53274.1}, BN
RC   {ECO:0000313|EMBL:AAZ53264.1}, CDF {ECO:0000313|EMBL:AAZ53266.1}, COP
RC   {ECO:0000313|EMBL:AAZ53275.1}, DA {ECO:0000313|EMBL:AAZ53267.1}, LEW
RC   {ECO:0000313|EMBL:AAZ53268.1}, LOU/M {ECO:0000313|EMBL:AAZ53269.1}, MW
RC   {ECO:0000313|EMBL:AAZ53270.1}, PVG {ECO:0000313|EMBL:AAZ53271.1}, SHR
RC   {ECO:0000313|EMBL:AAZ53272.1}, and WF {ECO:0000313|EMBL:AAZ53273.1};
RX   PubMed=17567587; DOI=10.1093/toxsci/kfm159;
RA   Walraven J.M., Barker D.F., Doll M.A., Hein D.W.;
RT   "Tissue expression and genomic sequences of rat N-acetyltransferases rNat1,
RT   rNat2, rNat3, and Functional characterization of a novel rNat3*2 genetic
RT   variant.";
RL   Toxicol. Sci. 99:413-421(2007).
CC   -!- SIMILARITY: Belongs to the arylamine N-acetyltransferase family.
CC       {ECO:0000256|ARBA:ARBA00006547, ECO:0000256|RuleBase:RU003452}.
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DR   EMBL; DQ133344; AAZ53264.1; -; Genomic_DNA.
DR   EMBL; DQ133346; AAZ53266.1; -; Genomic_DNA.
DR   EMBL; DQ133347; AAZ53267.1; -; Genomic_DNA.
DR   EMBL; DQ133348; AAZ53268.1; -; Genomic_DNA.
DR   EMBL; DQ133349; AAZ53269.1; -; Genomic_DNA.
DR   EMBL; DQ133350; AAZ53270.1; -; Genomic_DNA.
DR   EMBL; DQ133351; AAZ53271.1; -; Genomic_DNA.
DR   EMBL; DQ133352; AAZ53272.1; -; Genomic_DNA.
DR   EMBL; DQ133353; AAZ53273.1; -; Genomic_DNA.
DR   EMBL; DQ133354; AAZ53274.1; -; Genomic_DNA.
DR   EMBL; DQ133355; AAZ53275.1; -; Genomic_DNA.
DR   RefSeq; NP_001032392.1; NM_001037315.1.
DR   RefSeq; NP_001032393.1; NM_001037316.1.
DR   RefSeq; NP_446305.1; NM_053853.2.
DR   RefSeq; XP_006253063.1; XM_006253001.2.
DR   RefSeq; XP_006253064.1; XM_006253002.3.
DR   RefSeq; XP_006253066.1; XM_006253004.3.
DR   RefSeq; XP_017455467.1; XM_017599978.1.
DR   DNASU; 116631; -.
DR   GeneID; 116631; -.
DR   KEGG; rno:116631; -.
DR   CTD; 9; -.
DR   RGD; 70490; Nat1.
DR   HOGENOM; CLU_049918_3_0_1; -.
DR   OMA; IMYAMAQ; -.
DR   OrthoDB; 2696539at2759; -.
DR   GO; GO:0004060; F:arylamine N-acetyltransferase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.30.2140.20; -; 1.
DR   InterPro; IPR001447; Arylamine_N-AcTrfase.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   PANTHER; PTHR11786:SF2; ARYLAMINE N-ACETYLTRANSFERASE 1; 1.
DR   PANTHER; PTHR11786; N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE; 1.
DR   Pfam; PF00797; Acetyltransf_2; 1.
DR   PRINTS; PR01543; ANATRNSFRASE.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003452,
KW   ECO:0000313|EMBL:AAZ53275.1};
KW   Transferase {ECO:0000256|RuleBase:RU003452, ECO:0000313|EMBL:AAZ53275.1}.
SQ   SEQUENCE   290 AA;  33437 MW;  2897CC1F84B7D72A CRC64;
     MDIEAYFERI GYKNSVNKLD LATLTEVLQH QMRAVPFENL SMHCGEAMCL GLEATFDHIV
     RKKRGGWCLQ VNHLLYWALT KMGFETTMLG GYVYITPVNK YSSEMVHLLV QVTISDRNYI
     VDSAYGSSYQ MWEPLELTSG KDQPQVPAIF RLTEENGTWY LDQIRREQDV PNQEFVNSDL
     LEKSKYRKIY SFTLEPRTIE DFEYVNTYLQ TSPASVFVST SFCSLQTSEG VCCLIGSTLT
     SRRFSYKDNV DLVEFKSLTE EEIEDVLKTT FGISLEKKFV PKHGELVFTI
//