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Protein
Submitted name:

NtnH

Gene

ant

Organism
Clostridium botulinum
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
NtnHImported
Submitted name:
Peptidase M27Imported
Submitted name:
Type A progenitor toxin nontoxic-nonHAImported
Gene namesi
Name:antImported
Synonyms:ntnhImported
ORF Names:ACP52_06665Imported
OrganismiClostridium botulinumImported
Taxonomic identifieri1491 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000036889 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi583 ↔ 755Combined sources

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
ha70A5HZZ45EBI-16109965,EBI-16109901From Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A).

Protein-protein interaction databases

DIPiDIP-1006N.
IntActiQ45914. 1 interactor.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3V0AX-ray2.70B1-1193[»]
3V0BX-ray3.90B1-1193[»]
SMRiQ45914.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini848 – 1022Toxin_R_bind_NInterPro annotationAdd BLAST175
Domaini1032 – 1193NTNH_CInterPro annotationAdd BLAST162

Family and domain databases

InterProiView protein in InterPro
IPR000395. Bot/tetX.
IPR036248. Clostridium_toxin_transloc.
IPR013320. ConA-like_dom_sf.
IPR013677. Nontoxic_nonhemagglutn_C.
IPR012928. Toxin_rcpt-bd_N.
PfamiView protein in Pfam
PF08470. NTNH_C. 1 hit.
PF01742. Peptidase_M27. 1 hit.
PF07953. Toxin_R_bind_N. 1 hit.
PRINTSiPR00760. BONTOXILYSIN.
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF58091. SSF58091. 1 hit.

Sequencei

Sequence statusi: Complete.

Q45914-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNINDNLSIN SPVDNKNVVV VRARKTDTVF KAFKVAPNIW VAPERYYGES
60 70 80 90 100
LSIDEEYKVD GGIYDSNFLS QDSEKDKFLQ AIITLLKRIN STNAGEKLLS
110 120 130 140 150
LISTAIPFPY GYIGGGYYAP NMITFGSAPK SNKKLNSLIS STIPFPYAGY
160 170 180 190 200
RETNYLSSED NKSFYASNIV IFGPGANIVE NNTVFYKKED AENGMGTMTE
210 220 230 240 250
IWFQPFLTYK YDEFYIDPAI ELIKCLIKSL YFLYGIKPSD DLVIPYRLRS
260 270 280 290 300
ELENIEYSQL NIVDLLVSGG IDPKFINTDP YWFTDNYFSN AKKVFEDHRN
310 320 330 340 350
IYETEIEGNN AIGNDIKLRL KQKFRININD IWELNLNYFS KEFSIMMPDR
360 370 380 390 400
FNNALKHFYR KQYYKIDYPE NYSINGFVNG QINAQLSLSD RNQDIINKPE
410 420 430 440 450
EIINLLNGNN VSLMRSNIYG DGLKSTVDDF YSNYKIPYNR AYEYHFNNSN
460 470 480 490 500
DSSLDNVNIG VIDNIPEIID VNPYKENCDK FSPVQKITST REINTNIPWP
510 520 530 540 550
INYLQAQNTN NEKFSLSSDF VEVVSSKDKS LVYSFLSNVM FYLDSIKDNS
560 570 580 590 600
PIDTDKKYYL WLREIFRNYS FDITATQEIN TNCGINKVVT WFGKALNILN
610 620 630 640 650
TSDSFVEEFQ NLGAISLINK KENLSMPIIE SYEIPNDMLG LPLNDLNEKL
660 670 680 690 700
FNIYSKNTAY FKKIYYNFLD QWWTQYYSQY FDLICMAKRS VLAQETLIKR
710 720 730 740 750
IIQKKLSYLI GNSNISSDNL ALMNLTTTNT LRDISNESQI AMNNVDSFLN
760 770 780 790 800
NAAICVFESN IYPKFISFME QCINNINIKT KEFIQKCTNI NEDEKLQLIN
810 820 830 840 850
QNVFNSLDFE FLNIQNMKSL FSSETALLIK EETWPYELVL YAFKEPGNNV
860 870 880 890 900
IGDASGKNTS IEYSKDIGLV YGINSDALYL NGSNQSISFS NDFFENGLTN
910 920 930 940 950
SFSIYFWLRN LGKDTIKSKL IGSKEDNCGW EIYFQDTGLV FNMIDSNGNE
960 970 980 990 1000
KNIYLSDVSN NSWHYITISV DRLKEQLLIF IDDNLVANES IKEILNIYSS
1010 1020 1030 1040 1050
NIISLLSENN PSYIEGLTIL NKPTTSQEVL SNYFEVLNNS YIRDSNEERL
1060 1070 1080 1090 1100
EYNKTYQLYN YVFSDKPICE VKQNNNIYLT INNTNNLNLQ ASKFKLLSIN
1110 1120 1130 1140 1150
PNKQYVQKLD EVIISVLDNM EKYIDISEDN RLQLIDNKNN AKKMIISNDI
1160 1170 1180 1190
FISNCLTLSY NGKYICLSMK DENHNWMICN NDMSKYLYLW SFK
Length:1,193
Mass (Da):138,093
Last modified:November 1, 1996 - v1
Checksum:i9052B13E6E0F9848
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF461540 Genomic DNA. Translation: AAM75960.1.
AF488748 Genomic DNA. Translation: AAQ06330.1.
DQ409059 Genomic DNA. Translation: ABD65471.1.
KM017078 Genomic DNA. Translation: AIR72303.1.
D67030 Genomic DNA. Translation: BAA11050.1.
LGIK01000019 Genomic DNA. Translation: KON10585.1.
PIRiS68218.
RefSeqiWP_011948510.1. NZ_LHUL01000004.1.

Genome annotation databases

EnsemblBacteriaiKON10585; KON10585; ACP52_06665.
PATRICifig|1491.444.peg.1066.

Similar proteinsi

Entry informationi

Entry nameiQ45914_CLOBO
AccessioniPrimary (citable) accession number: Q45914
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 22, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported