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Reviewed, UniProtKB/Swiss-Prot Q45560 (FER_BACSC)

Last modified June 16, 2009. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Ferredoxin 7Fe
Alternative name(s):
    Seven-iron ferredoxin
Gene names
Name: fdxA
OrganismBacillus schlegelii
Taxonomic identifier1484 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesBacillaceaeBacillus

Protein attributes

Sequence length78 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level.

General annotation (Comments)

Cofactor

Binds 1 4Fe-4S cluster.

Binds 1 3Fe-4S cluster.

Subunit structure

Monomer.

Sequence similarities

Contains 2 4Fe-4S ferredoxin-type domains.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed
Chain2 – 7877Ferredoxin 7Fe
PRO_0000159172

Regions

Domain2 – 29284Fe-4S ferredoxin-type 1
Domain31 – 60304Fe-4S ferredoxin-type 2

Sites

Metal binding91Iron-sulfur 1 (3Fe-4S)
Metal binding171Iron-sulfur 1 (3Fe-4S)
Metal binding211Iron-sulfur 2 (4Fe-4S)
Metal binding401Iron-sulfur 2 (4Fe-4S)
Metal binding431Iron-sulfur 2 (4Fe-4S)
Metal binding461Iron-sulfur 2 (4Fe-4S)
Metal binding501Iron-sulfur 1 (3Fe-4S)

Experimental info

Mutagenesis141D → C: Transformation from a 7S to 8S ferredoxin. Ref.4

Secondary structure

................... 78
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q45560-1 [UniParc].

Last modified January 23, 2007. Version 2.
Checksum: 3295879B2E8C2BAA

FASTA788,874
        10         20         30         40         50         60 
MAYVITEPCI GTKDASCVEV CPVDCIHEGE DQYYIDPDVC IDCGACEAVC PVSAIYHEDF 

        70 
VPEEWKSYIQ KNRDFFKK 

« Hide

References

[1]"Cloning and expression of the gene encoding the 7Fe type ferredoxin from a thermophilic hydrogen oxidizing bacterium, Bacillus schlegelii."
Aono S., Nakamura S., Aono R., Okura I.
Biochem. Biophys. Res. Commun. 201:938-942(1994) [PubMed: 8003034] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 43741 / DSM 2000 / MA-48.
[2]"Purification and characterization of a 7Fe ferredoxin from a thermophilic hydrogen-oxidizing bacterium, Bacillus schlegelii."
Aono S., Kurita H., Uno S., Okura I.
J. Biochem. 112:792-795(1992) [PubMed: 1338329] [Abstract]
Cited for: CHARACTERIZATION.
[3]"Solution structure of the oxidized Fe7S8 ferredoxin from the thermophilic bacterium Bacillus schlegelii by 1H NMR spectroscopy."
Aono S., Bentrop D., Bertini I., Donaire A., Luchinat C., Niikura Y., Rosato A.
Biochemistry 37:9812-9826(1998) [PubMed: 9657695] [Abstract]
Cited for: STRUCTURE BY NMR.
Strain: ATCC 43741 / DSM 2000 / MA-48.
[4]"The D13C variant of Bacillus schlegelii 7Fe ferredoxin is an 8Fe ferredoxin as revealed by 1H-NMR spectroscopy."
Aono S., Bentrop D., Bertini I., Luchinat C., Macinai R.
FEBS Lett. 412:501-505(1997) [PubMed: 9276454] [Abstract]
Cited for: MUTAGENESIS OF ASP-14.
+Additional computationally mapped references.

Cross-references

Sequence databases

D29804 Genomic DNA. Translation: BAA06187.1.
PIRJC2496.

3D structure databases

EntryMethodResolution (Å)ChainPositionsPDBsum
1BC6NMR-A2-78[»]
1BD6NMR-A2-78[»]
1BQXNMR-A2-77[»]
1BWENMR-A2-78[»]
ModBaseSearch...

Family and domain databases

InterProIPR017896. 4Fe4S_Fe-S-bd.
IPR001450. 4Fe4S_Fe_S_bd_subgr.
IPR017900. 4Fe4S_Fe_S_CS.
IPR000813. 7Fe_ferredoxin.
[Graphical view]
PfamPF00037. Fer4. 1 hit.
[Graphical view]
PRINTSPR00354. 7FE8SFRDOXIN.
PROSITEPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFER_BACSC
AccessionPrimary (citable) accession number: Q45560
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 23, 2007
Last modified: June 16, 2009
This is version 66 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents