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Protein

Choline transport system permease protein OpuBB

Gene

opuBB

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in a high affinity multicomponent binding-protein-dependent transport system for choline; probably responsible for the translocation of the substrate across the membrane.1 Publication

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Enzyme and pathway databases

BioCyciBSUB:BSU33720-MONOMER.

Protein family/group databases

TCDBi3.A.1.12.3. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Choline transport system permease protein OpuBB
Gene namesi
Name:opuBB
Synonyms:proW
Ordered Locus Names:BSU33720
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei23 – 4321HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei52 – 7423HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei84 – 10118HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei128 – 14821HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei150 – 17021HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei180 – 20021HelicalPROSITE-ProRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 217217Choline transport system permease protein OpuBBPRO_0000060154Add
BLAST

Proteomic databases

PaxDbiQ45461.

Expressioni

Inductioni

Repressed by GbsR.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100018296.

Structurei

3D structure databases

ProteinModelPortaliQ45461.
SMRiQ45461. Positions 15-198.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini19 – 198180ABC transmembrane type-1PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E90. Bacteria.
COG1174. LUCA.
HOGENOMiHOG000012907.
InParanoidiQ45461.
KOiK05846.
OMAiIAIMNMP.
PhylomeDBiQ45461.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q45461-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHHIVQFLQT NGGELLYKTY EHITISLIAV ILGVLVAVPL GVVLTRMKKG
60 70 80 90 100
AGTIIGIVNI IQTLPSLAIL AFFIPLLGVG KVPAIVALFF YSVLPILRNT
110 120 130 140 150
YTGIRGVNKN LLESGKGIGM TPAEQVRLVE LPLAAPVIMA GIRTSTIYLI
160 170 180 190 200
GWATLASFIG GGGLGDYIFI GLNLYQPEYI IGGAVPVTIL AIVIDYVLAV
210
AERKLTPAGM QRLKELS
Length:217
Mass (Da):23,163
Last modified:May 30, 2000 - v2
Checksum:iA7915A2D22ABA58E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti67 – 726LAILAF → PDSRHI in AAB01533 (PubMed:7592481).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti5 – 51V → I in strain: ATCC 6633 / PCI 219.
Natural varianti130 – 1312EL → DV in strain: ATCC 6633 / PCI 219.
Natural varianti201 – 2011A → T in strain: ATCC 6633 / PCI 219.
Natural varianti216 – 2161L → V in strain: ATCC 6633 / PCI 219.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38418 Genomic DNA. Translation: AAB01533.1.
AF008930 Genomic DNA. Translation: AAC14357.1.
AL009126 Genomic DNA. Translation: CAB15377.1.
PIRiH69669.
RefSeqiNP_391252.1. NC_000964.3.
WP_003228370.1. NZ_JNCM01000033.1.

Genome annotation databases

EnsemblBacteriaiCAB15377; CAB15377; BSU33720.
GeneIDi936225.
KEGGibsu:BSU33720.
PATRICi18978746. VBIBacSub10457_3536.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38418 Genomic DNA. Translation: AAB01533.1.
AF008930 Genomic DNA. Translation: AAC14357.1.
AL009126 Genomic DNA. Translation: CAB15377.1.
PIRiH69669.
RefSeqiNP_391252.1. NC_000964.3.
WP_003228370.1. NZ_JNCM01000033.1.

3D structure databases

ProteinModelPortaliQ45461.
SMRiQ45461. Positions 15-198.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100018296.

Protein family/group databases

TCDBi3.A.1.12.3. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiQ45461.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB15377; CAB15377; BSU33720.
GeneIDi936225.
KEGGibsu:BSU33720.
PATRICi18978746. VBIBacSub10457_3536.

Phylogenomic databases

eggNOGiENOG4105E90. Bacteria.
COG1174. LUCA.
HOGENOMiHOG000012907.
InParanoidiQ45461.
KOiK05846.
OMAiIAIMNMP.
PhylomeDBiQ45461.

Enzyme and pathway databases

BioCyciBSUB:BSU33720-MONOMER.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiOPUBB_BACSU
AccessioniPrimary (citable) accession number: Q45461
Secondary accession number(s): O34670
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 30, 2000
Last modified: September 7, 2016
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.