Q45408 (EPSP_RALSL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable low molecular weight protein-tyrosine-phosphatase EpsP
EC=3.1.3.48

Gene names

Name:

epsP

Organism

Ralstonia solanacearum (Pseudomonas solanacearum)

Taxonomic identifier

305 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Ralstonia

Protein attributes

Sequence length	145 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May be involved in assembly or function of the EPS I polymerization/export complex and/or the EpsB ATPase. Alternatively it may function in the removal of the terminal phosphate from C55-isoprenyl pyrophosphate in order to recycle the C55-isoprenyl phosphate lipid carrier used in the synthesis of polysaccharide repeat units.
Catalytic activity	Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
Pathway	Glycan metabolism; exopolysaccharide biosynthesis.
Sequence similarities	Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

Ontologies

Keywords
Biological process	Lipopolysaccharide biosynthesis
Molecular function	Hydrolase Protein phosphatase
Gene Ontology (GO)
Biological_process	lipopolysaccharide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW peptidyl-tyrosine dephosphorylation Inferred from electronic annotation. Source: GOC
Molecular_function	protein tyrosine phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 145	145	Probable low molecular weight protein-tyrosine-phosphatase EpsP		PRO_0000046571
Sites
	Active site	9	1	Nucleophile By similarity
	Active site	14	1	By similarity
	Active site	114	1	Proton donor By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q45408 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: E2E4D3947CB750AE	FASTA	145	15,711
	10 20 30 40 50 60 MIKTILVVCI GNICRSPMAQ ALLRQALPGV SVISAGIGAL SGYPADPSAV EVMAQHGIDI 70 80 90 100 110 120 SEHRAQQLTG SLVNRADLIL VMGGAQKREI QARHPSKTGS VFRLGEMEQF DIDDPYRKQM 130 140 MAFEDALAMI QRGVDAWVPR IRALG

References

[1]	"Molecular characterization of the eps gene cluster of Pseudomonas solanacearum and its transcriptional regulation at a single promoter." Huang J., Schell M. Mol. Microbiol. 16:977-989(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: AW.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U17898 Genomic DNA. Translation: AAA91623.1.
PIR	S77635.
3D structure databases
ProteinModelPortal	Q45408.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	COG0394.
Enzyme and pathway databases
UniPathway	UPA00631.
Family and domain databases
InterPro	IPR023485. Ptyr_pPase_SF. IPR000106. Tyr_phospatase/Ars_reductase. IPR017867. Tyr_phospatase_low_mol_wt. [Graphical view]
PANTHER	PTHR11717. PTHR11717. 1 hit.
Pfam	PF01451. LMWPc. 1 hit. [Graphical view]
PRINTS	PR00719. LMWPTPASE.
SMART	SM00226. LMWPc. 1 hit. [Graphical view]
SUPFAM	SSF52788. Tyr_Pase_low_mol_wt. 1 hit.
ProtoNet	Search...

Entry information

Entry name

EPSP_RALSL

Accession

Primary (citable) accession number: Q45408

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	April 3, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program