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Q45408 (EPSP_RALSL) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable low molecular weight protein-tyrosine-phosphatase EpsP

EC=3.1.3.48
Gene names
Name:epsP
OrganismRalstonia solanacearum (Pseudomonas solanacearum)
Taxonomic identifier305 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia

Protein attributes

Sequence length145 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

May be involved in assembly or function of the EPS I polymerization/export complex and/or the EpsB ATPase. Alternatively it may function in the removal of the terminal phosphate from C55-isoprenyl pyrophosphate in order to recycle the C55-isoprenyl phosphate lipid carrier used in the synthesis of polysaccharide repeat units.

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Pathway

Glycan metabolism; exopolysaccharide biosynthesis.

Sequence similarities

Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

Ontologies

Keywords
   Biological processLipopolysaccharide biosynthesis
   Molecular functionHydrolase
Protein phosphatase
Gene Ontology (GO)
   Biological_processlipopolysaccharide biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionprotein tyrosine phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 145145Probable low molecular weight protein-tyrosine-phosphatase EpsP
PRO_0000046571

Sites

Active site91Nucleophile By similarity
Active site141 By similarity
Active site1141Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q45408 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: E2E4D3947CB750AE

FASTA14515,711
        10         20         30         40         50         60 
MIKTILVVCI GNICRSPMAQ ALLRQALPGV SVISAGIGAL SGYPADPSAV EVMAQHGIDI 

        70         80         90        100        110        120 
SEHRAQQLTG SLVNRADLIL VMGGAQKREI QARHPSKTGS VFRLGEMEQF DIDDPYRKQM 

       130        140 
MAFEDALAMI QRGVDAWVPR IRALG 

« Hide

References

[1]"Molecular characterization of the eps gene cluster of Pseudomonas solanacearum and its transcriptional regulation at a single promoter."
Huang J., Schell M.
Mol. Microbiol. 16:977-989(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: AW.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U17898 Genomic DNA. Translation: AAA91623.1.
PIRS77635.

3D structure databases

ProteinModelPortalQ45408.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGCOG0394.

Enzyme and pathway databases

UniPathwayUPA00631.

Family and domain databases

InterProIPR023485. Ptyr_pPase_SF.
IPR000106. Tyr_phospatase/Ars_reductase.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view]
PANTHERPTHR11717. PTHR11717. 1 hit.
PfamPF01451. LMWPc. 1 hit.
[Graphical view]
PRINTSPR00719. LMWPTPASE.
SMARTSM00226. LMWPc. 1 hit.
[Graphical view]
SUPFAMSSF52788. SSF52788. 1 hit.
ProtoNetSearch...

Entry information

Entry nameEPSP_RALSL
AccessionPrimary (citable) accession number: Q45408
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: April 16, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways