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Protein

PTS system cellobiose-specific EIIC component

Gene

celB

Organism
Geobacillus stearothermophilus (Bacillus stearothermophilus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CelABD PTS system is involved in cellobiose transport.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processPhosphotransferase system, Sugar transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
PTS system cellobiose-specific EIIC component1 Publication
Alternative name(s):
Cellobiose permease IIC component1 Publication
EIIC-Cel1 Publication
Gene namesi
Name:celB1 Publication
OrganismiGeobacillus stearothermophilus (Bacillus stearothermophilus)
Taxonomic identifieri1422 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Subcellular locationi

Q45400:
  • Cell membrane PROSITE-ProRule annotation; Multi-pass membrane protein PROSITE-ProRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei31 – 51HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei72 – 92HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei104 – 124HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei138 – 158HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei187 – 207HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei227 – 247HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei250 – 270HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei293 – 313HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei347 – 367HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei407 – 427HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001864831 – 451PTS system cellobiose-specific EIIC componentAdd BLAST451

Structurei

3D structure databases

SMRiQ45400.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 423PTS EIIC type-3PROSITE-ProRule annotationAdd BLAST416

Domaini

The EIIC type-3 domain forms the PTS system translocation channel and contains the specific substrate-binding site.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

InterProiView protein in InterPro
IPR003352. PTS_EIIC.
IPR004501. PTS_EIIC_3.
IPR004796. PTS_IIC_cello.
PfamiView protein in Pfam
PF02378. PTS_EIIC. 1 hit.
PIRSFiPIRSF006351. PTS_EIIC-Cellobiose. 1 hit.
TIGRFAMsiTIGR00359. cello_pts_IIC. 1 hit.
TIGR00410. lacE. 1 hit.
PROSITEiView protein in PROSITE
PS51105. PTS_EIIC_TYPE_3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q45400-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRFIRMLED RVMPVAGKIA EQRHLQAIRD GIILSMPLLI IGSLFLIVGF
60 70 80 90 100
LPIPGYNEWM AKWFGEHWLD KLLYPVGATF DIMALVVSFG VAYRLAEKYK
110 120 130 140 150
VDALSAGAIS LAAFLLATPY QVPFTPEGAK ETIMVSGGIP VQWVGSKGLF
160 170 180 190 200
VAMILAIVST EIYRKIIQKN IVIKLPDGVP PAVARSFVAL IPGAAVLVVV
210 220 230 240 250
WVARLILEMT PFESFHNIVS VLLNKPLSVL GGSVFGAIVA VLLVQLLWST
260 270 280 290 300
GLHGAAIVGG VMGPIWLSLM DENRMVFQQN PNAELPNVIT QQFFDLWIYI
310 320 330 340 350
GGSGATLALA LTMMFRARSR QLKSLGRLAI APGIFNINEP ITFGMPIVMN
360 370 380 390 400
PLLIIPFILV PVVLVVVSYA AMATGLVAKP SGVAVPWTTP IVISGYLATG
410 420 430 440 450
GKISGSILQI VNFFIAFAIY YPFFSIWDKQ KAAEEQADPT ISSGAGATHS

L
Length:451
Mass (Da):48,805
Last modified:November 1, 1996 - v1
Checksum:i18C3EBC0840D75AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U07818 Unassigned DNA. Translation: AAA17390.1.
PIRiC49898.

Similar proteinsi

Entry informationi

Entry nameiPTEC_GEOSE
AccessioniPrimary (citable) accession number: Q45400
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: March 15, 2017
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program