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Q45321 (OM25_BRUME) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
25 kDa outer-membrane immunogenic protein
Gene names
Name:omp25
Ordered Locus Names:BMEI1249
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length213 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Subcellular location

Cell outer membrane.

Sequence similarities

Belongs to the Omp25/RopB family.

Ontologies

Keywords
   Cellular componentCell outer membrane
Membrane
   DomainSignal
Transmembrane
Transmembrane beta strand
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcell outer membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

integral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 21319025 kDa outer-membrane immunogenic protein
PRO_0000021880

Sequences

Sequence LengthMass (Da)Tools
Q45321 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 59003CF46F6D0ED3

FASTA21323,185
        10         20         30         40         50         60 
MRTLKSLVIV SAALLPFSAT AFAADAIQEQ PPVPAPVEVA PQYSWAGGYT GLYLGYGWNK 

        70         80         90        100        110        120 
AKTSTVGSIK PDDWKAGAFA GWNFQQDQIV YGVEGDAGYS WAKKSKDGLE VKQGFEGSLR 

       130        140        150        160        170        180 
ARVGYDLNPV MPYLTAGIAG SQIKLNNGLD DESKFRVGWT AGAGLEAKLT DNILGRVEYR 

       190        200        210 
YTQYGNKNYD LAGTTVRNKL DTQDFRVGIG YKF 

« Hide

References

« Hide 'large scale' references
[1]"Nucleotide sequence and expression of the gene encoding the major 25-kilodalton outer membrane protein of Brucella ovis: evidence for antigenic shift, compared with other Brucella species, due to a deletion in the gene."
Cloeckaert A., Verger J.M., Grayon M., Zygmunt M.S., Grepinet O.
Infect. Immun. 64:2047-2055(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 16M / ATCC 23456 / NCTC 10094.
[2]"The genome sequence of the facultative intracellular pathogen Brucella melitensis."
DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. expand/collapse author list , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R.
Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 16M / ATCC 23456 / NCTC 10094.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U33003 Genomic DNA. Translation: AAB06701.1.
AE008917 Genomic DNA. Translation: AAL52430.1.
PIRAC3408.
RefSeqNP_540166.1. NC_003317.1.

3D structure databases

ProteinModelPortalQ45321.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224914.BMEI1249.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL52430; AAL52430; BMEI1249.
GeneID1196960.
KEGGbme:BMEI1249.
PATRIC17797483. VBIBruMel146950_0560.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000135658.
KOK16079.
OMARFSSSND.
OrthoDBEOG69KTWT.

Family and domain databases

Gene3D2.40.160.20. 1 hit.
InterProIPR000758. Enterovir_OMP.
IPR011250. OMP/PagP_b-brl.
IPR027385. OMP_b-brl.
[Graphical view]
PfamPF13505. OMP_b-brl. 1 hit.
[Graphical view]
SUPFAMSSF56925. SSF56925. 1 hit.
ProtoNetSearch...

Other

PROQ45321.

Entry information

Entry nameOM25_BRUME
AccessionPrimary (citable) accession number: Q45321
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: May 14, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella melitensis

Brucella melitensis (strain 16M): entries and gene names