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Protein

25 kDa outer-membrane immunogenic protein

Gene

omp25

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
25 kDa outer-membrane immunogenic protein
Gene namesi
Name:omp25
Ordered Locus Names:BMEI1249
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence AnalysisAdd
BLAST
Chaini24 – 21319025 kDa outer-membrane immunogenic proteinPRO_0000021880Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224914.BAWG_0961.

Structurei

3D structure databases

ProteinModelPortaliQ45321.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Omp25/RopB family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Phylogenomic databases

HOGENOMiHOG000135658.
KOiK16079.
OMAiRFSSSND.
OrthoDBiEOG69KTWT.

Family and domain databases

Gene3Di2.40.160.20. 1 hit.
InterProiIPR000758. Enterovir_OMP.
IPR011250. OMP/PagP_b-brl.
IPR027385. OMP_b-brl.
[Graphical view]
PfamiPF13505. OMP_b-brl. 1 hit.
[Graphical view]
SUPFAMiSSF56925. SSF56925. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q45321-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTLKSLVIV SAALLPFSAT AFAADAIQEQ PPVPAPVEVA PQYSWAGGYT
60 70 80 90 100
GLYLGYGWNK AKTSTVGSIK PDDWKAGAFA GWNFQQDQIV YGVEGDAGYS
110 120 130 140 150
WAKKSKDGLE VKQGFEGSLR ARVGYDLNPV MPYLTAGIAG SQIKLNNGLD
160 170 180 190 200
DESKFRVGWT AGAGLEAKLT DNILGRVEYR YTQYGNKNYD LAGTTVRNKL
210
DTQDFRVGIG YKF
Length:213
Mass (Da):23,185
Last modified:November 1, 1996 - v1
Checksum:i59003CF46F6D0ED3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U33003 Genomic DNA. Translation: AAB06701.1.
AE008917 Genomic DNA. Translation: AAL52430.1.
PIRiAC3408.
RefSeqiNP_540166.1. NC_003317.1.
WP_004683466.1. NZ_GG703778.1.

Genome annotation databases

EnsemblBacteriaiAAL52430; AAL52430; BMEI1249.
KEGGibme:BMEI1249.
PATRICi17797483. VBIBruMel146950_0560.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U33003 Genomic DNA. Translation: AAB06701.1.
AE008917 Genomic DNA. Translation: AAL52430.1.
PIRiAC3408.
RefSeqiNP_540166.1. NC_003317.1.
WP_004683466.1. NZ_GG703778.1.

3D structure databases

ProteinModelPortaliQ45321.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224914.BAWG_0961.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL52430; AAL52430; BMEI1249.
KEGGibme:BMEI1249.
PATRICi17797483. VBIBruMel146950_0560.

Phylogenomic databases

HOGENOMiHOG000135658.
KOiK16079.
OMAiRFSSSND.
OrthoDBiEOG69KTWT.

Miscellaneous databases

PROiQ45321.

Family and domain databases

Gene3Di2.40.160.20. 1 hit.
InterProiIPR000758. Enterovir_OMP.
IPR011250. OMP/PagP_b-brl.
IPR027385. OMP_b-brl.
[Graphical view]
PfamiPF13505. OMP_b-brl. 1 hit.
[Graphical view]
SUPFAMiSSF56925. SSF56925. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Nucleotide sequence and expression of the gene encoding the major 25-kilodalton outer membrane protein of Brucella ovis: evidence for antigenic shift, compared with other Brucella species, due to a deletion in the gene."
    Cloeckaert A., Verger J.M., Grayon M., Zygmunt M.S., Grepinet O.
    Infect. Immun. 64:2047-2055(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiOM25_BRUME
AccessioniPrimary (citable) accession number: Q45321
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: June 24, 2015
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.