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Q45321

- OM25_BRUME

UniProt

Q45321 - OM25_BRUME

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Protein
25 kDa outer-membrane immunogenic protein
Gene
omp25, BMEI1249
Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
25 kDa outer-membrane immunogenic protein
Gene namesi
Name:omp25
Ordered Locus Names:BMEI1249
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419: Chromosome I

Subcellular locationi

GO - Cellular componenti

  1. cell outer membrane Source: UniProtKB-SubCell
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323 Reviewed prediction
Add
BLAST
Chaini24 – 21319025 kDa outer-membrane immunogenic protein
PRO_0000021880Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224914.BMEI1249.

Structurei

3D structure databases

ProteinModelPortaliQ45321.

Family & Domainsi

Sequence similaritiesi

Belongs to the Omp25/RopB family.

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Phylogenomic databases

HOGENOMiHOG000135658.
KOiK16079.
OMAiRFSSSND.
OrthoDBiEOG69KTWT.

Family and domain databases

Gene3Di2.40.160.20. 1 hit.
InterProiIPR000758. Enterovir_OMP.
IPR011250. OMP/PagP_b-brl.
IPR027385. OMP_b-brl.
[Graphical view]
PfamiPF13505. OMP_b-brl. 1 hit.
[Graphical view]
SUPFAMiSSF56925. SSF56925. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q45321-1 [UniParc]FASTAAdd to Basket

« Hide

MRTLKSLVIV SAALLPFSAT AFAADAIQEQ PPVPAPVEVA PQYSWAGGYT    50
GLYLGYGWNK AKTSTVGSIK PDDWKAGAFA GWNFQQDQIV YGVEGDAGYS 100
WAKKSKDGLE VKQGFEGSLR ARVGYDLNPV MPYLTAGIAG SQIKLNNGLD 150
DESKFRVGWT AGAGLEAKLT DNILGRVEYR YTQYGNKNYD LAGTTVRNKL 200
DTQDFRVGIG YKF 213
Length:213
Mass (Da):23,185
Last modified:November 1, 1996 - v1
Checksum:i59003CF46F6D0ED3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U33003 Genomic DNA. Translation: AAB06701.1.
AE008917 Genomic DNA. Translation: AAL52430.1.
PIRiAC3408.
RefSeqiNP_540166.1. NC_003317.1.

Genome annotation databases

EnsemblBacteriaiAAL52430; AAL52430; BMEI1249.
GeneIDi1196960.
KEGGibme:BMEI1249.
PATRICi17797483. VBIBruMel146950_0560.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U33003 Genomic DNA. Translation: AAB06701.1 .
AE008917 Genomic DNA. Translation: AAL52430.1 .
PIRi AC3408.
RefSeqi NP_540166.1. NC_003317.1.

3D structure databases

ProteinModelPortali Q45321.
ModBasei Search...

Protein-protein interaction databases

STRINGi 224914.BMEI1249.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL52430 ; AAL52430 ; BMEI1249 .
GeneIDi 1196960.
KEGGi bme:BMEI1249.
PATRICi 17797483. VBIBruMel146950_0560.

Phylogenomic databases

HOGENOMi HOG000135658.
KOi K16079.
OMAi RFSSSND.
OrthoDBi EOG69KTWT.

Miscellaneous databases

PROi Q45321.

Family and domain databases

Gene3Di 2.40.160.20. 1 hit.
InterProi IPR000758. Enterovir_OMP.
IPR011250. OMP/PagP_b-brl.
IPR027385. OMP_b-brl.
[Graphical view ]
Pfami PF13505. OMP_b-brl. 1 hit.
[Graphical view ]
SUPFAMi SSF56925. SSF56925. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Nucleotide sequence and expression of the gene encoding the major 25-kilodalton outer membrane protein of Brucella ovis: evidence for antigenic shift, compared with other Brucella species, due to a deletion in the gene."
    Cloeckaert A., Verger J.M., Grayon M., Zygmunt M.S., Grepinet O.
    Infect. Immun. 64:2047-2055(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiOM25_BRUME
AccessioniPrimary (citable) accession number: Q45321
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: May 14, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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