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Q45101

- O16G_BACCO

UniProt

Q45101 - O16G_BACCO

Protein

Oligo-1,6-glucosidase

Gene

malL

Organism
Bacillus coagulans
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei199 – 1991NucleophileBy similarity
    Active sitei255 – 2551Proton donorBy similarity
    Sitei332 – 3321Transition state stabilizerBy similarity

    GO - Molecular functioni

    1. cation binding Source: InterPro
    2. oligo-1,6-glucosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Enzyme and pathway databases

    BioCyciRETL1328306-WGS:GSTH-3141-MONOMER.
    RETL1328306-WGS:GSTH-712-MONOMER.

    Protein family/group databases

    CAZyiGH13. Glycoside Hydrolase Family 13.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Oligo-1,6-glucosidase (EC:3.2.1.10)
    Alternative name(s):
    Dextrin 6-alpha-D-glucanohydrolase
    Oligosaccharide alpha-1,6-glucosidase
    Sucrase-isomaltase
    Short name:
    Isomaltase
    Gene namesi
    Name:malL
    OrganismiBacillus coagulans
    Taxonomic identifieri1398 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 555555Oligo-1,6-glucosidasePRO_0000054314Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ45101.
    SMRiQ45101. Positions 2-554.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 13 family.Curated

    Family and domain databases

    Gene3Di2.60.40.1180. 1 hit.
    3.20.20.80. 2 hits.
    InterProiIPR022567. DUF3459.
    IPR015902. Glyco_hydro_13.
    IPR013780. Glyco_hydro_13_b.
    IPR006047. Glyco_hydro_13_cat_dom.
    IPR006589. Glyco_hydro_13_sub_cat_dom.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PANTHERiPTHR10357. PTHR10357. 1 hit.
    PfamiPF00128. Alpha-amylase. 1 hit.
    PF11941. DUF3459. 1 hit.
    [Graphical view]
    SMARTiSM00642. Aamy. 1 hit.
    [Graphical view]
    SUPFAMiSSF51445. SSF51445. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q45101-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTEWWKKAVV YQIYPRSFYD TNGDGIGDLR GIMDKLDYLK TLGIDCIWIS    50
    PVYDSPQDDN GYDIRDYRKI DKMFGTNEDM DRLLDEAHAR GIKIVMDLVV 100
    NHTSDEHAWF VESRKSKDNP YRDFYFWKDP KPDGTPPNNW GSMFSGSAWE 150
    YDETTGQYYL HYFSKKQPDL NWENEKVRKE IYDMMKFWMD KGVDGWRMDV 200
    IGSISKFLDF PDYELPEGQK YGIGKYHANG PRLHAFIQEM NREVLSKYDC 250
    MTVGEAIGSD VEIARKYTGP DRHELNMIFN FEHMDVDTKP GSPAGKWALK 300
    PFDLVELKQI LSRWQYELAD TGWNALYFEN HDQARVVSRW GNDTTYRAEC 350
    AKAFATILHG LKGTPFIYQG EEIGMVNADL ELEEYDDIEI RNAYQELVME 400
    NQIMSKDEFL TAVRKKGRDN ARTPMQWDGS FNAGFTTGTP WLKVNSRYSE 450
    INVAKALQEP DSIFYYYQSL IKLRHSYDVF TDGRYELLMP DHPHLYVYTR 500
    ENESEKLLVA ANLSENTVSF DQPDDNWKLL LGNYEDTGTS TLFRPYEAAI 550
    YYLEK 555
    Length:555
    Mass (Da):64,991
    Last modified:November 1, 1996 - v1
    Checksum:iCE2BB1D7B4E226D8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D78342 Genomic DNA. Translation: BAA11354.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D78342 Genomic DNA. Translation: BAA11354.1 .

    3D structure databases

    ProteinModelPortali Q45101.
    SMRi Q45101. Positions 2-554.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GH13. Glycoside Hydrolase Family 13.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    BioCyci RETL1328306-WGS:GSTH-3141-MONOMER.
    RETL1328306-WGS:GSTH-712-MONOMER.

    Family and domain databases

    Gene3Di 2.60.40.1180. 1 hit.
    3.20.20.80. 2 hits.
    InterProi IPR022567. DUF3459.
    IPR015902. Glyco_hydro_13.
    IPR013780. Glyco_hydro_13_b.
    IPR006047. Glyco_hydro_13_cat_dom.
    IPR006589. Glyco_hydro_13_sub_cat_dom.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    PANTHERi PTHR10357. PTHR10357. 1 hit.
    Pfami PF00128. Alpha-amylase. 1 hit.
    PF11941. DUF3459. 1 hit.
    [Graphical view ]
    SMARTi SM00642. Aamy. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51445. SSF51445. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Analysis of the critical sites for protein thermostabilization by proline substitution in oligo-1,6-glucosidase from Bacillus coagulans ATCC 7050 and the evolutionary consideration of proline residues."
      Watanabe K., Kitamura K., Suzuki Y.
      Appl. Environ. Microbiol. 62:2066-2073(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 7050 / DSM 1 / JCM 2257 / NCIB 9365 / NCTC 10334.

    Entry informationi

    Entry nameiO16G_BACCO
    AccessioniPrimary (citable) accession number: Q45101
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3