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Q45010 (BMPA_BORBU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Basic membrane protein A
Alternative name(s):
Immunodominant antigen P39
Gene names
Name:bmpA
Ordered Locus Names:BB_0383
OrganismBorrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680) [Reference proteome] [HAMAP]
Taxonomic identifier224326 [NCBI]
Taxonomic lineageBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeBorreliaBorrelia burgdorferi group

Protein attributes

Sequence length339 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Not known; immunogenic protein.

Subcellular location

Cell membrane; Lipid-anchor Probable.

Sequence similarities

Belongs to the BMP lipoprotein family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainSignal
   PTMLipoprotein
Palmitate
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentplasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1717 Probable
Chain18 – 339322Basic membrane protein A
PRO_0000017996

Amino acid modifications

Lipidation181N-palmitoyl cysteine Probable
Lipidation181S-diacylglycerol cysteine Probable

Natural variations

Natural variant2781F → S in strain: 297.

Sequences

Sequence LengthMass (Da)Tools
Q45010 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: A9581868CA7DB923

FASTA33936,968
        10         20         30         40         50         60 
MNKILLLILL ESIVFLSCSG KGSLGSEIPK VSLIIDGTFD DKSFNESALN GVKKVKEEFK 

        70         80         90        100        110        120 
IELVLKESSS NSYLSDLEGL KDAGSDLIWL IGYRFSDVAK VAALQNPDMK YAIIDPIYSN 

       130        140        150        160        170        180 
DPIPANLVGM TFRAQEGAFL TGYIAAKLSK TGKIGFLGGI EGEIVDAFRY GYEAGAKYAN 

       190        200        210        220        230        240 
KDIKISTQYI GSFADLEAGR SVATRMYSDE IDIIHHAAGL GGIGAIEVAK ELGSGHYIIG 

       250        260        270        280        290        300 
VDEDQAYLAP DNVITSTTKD VGRALNIFTS NHLKTNTFEG GKLINYGLKE GVVGFVRNPK 

       310        320        330 
MISFELEKEI DNLSSKIINK EIIVPSNKES YEKFLKEFI 

« Hide

References

« Hide 'large scale' references
[1]"Nucleotide sequence and analysis of the gene in Borrelia burgdorferi encoding the immunogenic P39 antigen."
Simpson W.J., Cieplak W., Schrumpf M.E., Barbour A.G., Schwan T.G.
FEMS Microbiol. Lett. 119:381-388(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: Sh-2-82.
[2]"Identification and mapping of a chromosomal gene cluster of Borrelia burgdorferi containing genes expressed in vivo."
Aron L., Toth C., Godfrey H.P., Cabello F.C.
FEMS Microbiol. Lett. 145:309-314(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 53899 / 297.
[3]Orlova T., Bugrysheva J., Novikova S., Godfrey H.P., Cabello F.C.
Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: BL206.
[4]"Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi."
Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A., Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L., Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L., Peterson J.D., Kerlavage A.R., Quackenbush J. expand/collapse author list , Salzberg S.L., Hanson M., van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F., Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C., Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B., Smith H.O., Venter J.C.
Nature 390:580-586(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35210 / B31 / CIP 102532 / DSM 4680.
[5]"Conservation of gene arrangement and an unusual organization of rRNA genes in the linear chromosomes of the Lyme disease spirochaetes Borrelia burgdorferi, B. garinii and B. afzelii."
Ojaimi C., Davidson B.E., Saint-Girons I., Old I.G.
Microbiology 140:2931-2940(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 248-339.
Strain: 212.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L24194 Genomic DNA. Translation: AAA72406.1.
U49938 Genomic DNA. Translation: AAC44712.1.
AF400111 Genomic DNA. Translation: AAM89914.1.
AE000783 Genomic DNA. Translation: AAC66757.1.
L35050 Genomic DNA. Translation: AAC41401.1.
PIRF70147.
RefSeqNP_212517.1. NC_001318.1.

3D structure databases

ProteinModelPortalQ45010.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224326.BB0383.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC66757; AAC66757; BB_0383.
GeneID1195220.
KEGGbbu:BB_0383.
PATRIC20557376. VBIBorBur75917_0778.

Phylogenomic databases

eggNOGCOG1744.
KOK07335.
OMAIHHAAGL.
OrthoDBEOG6Z9B3D.
ProtClustDBCLSK785734.

Enzyme and pathway databases

BioCycBBUR224326:G9SO-380-MONOMER.

Family and domain databases

InterProIPR003760. Bmp.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamPF02608. Bmp. 1 hit.
[Graphical view]
SUPFAMSSF53822. SSF53822. 1 hit.
ProtoNetSearch...

Entry information

Entry nameBMPA_BORBU
AccessionPrimary (citable) accession number: Q45010
Secondary accession number(s): P94249, Q44857
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: February 19, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families