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Reviewed, UniProtKB/Swiss-Prot Q44549 (FENR_ANAVT)

Last modified November 3, 2009. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Ferredoxin--NADP reductase
      Short name=FNR
    EC=1.18.1.2
Gene names
Name: petH
Ordered Locus Names: Ava_0782
OrganismAnabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]
Taxonomic identifier240292 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

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Protein attributes

Sequence length440 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH.

Cofactor

FAD.

Subcellular location

Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side By similarity. Note: May be bound to the thylakoid membrane or anchored to the thylakoid-bound phycobilisomes By similarity.

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 1 family.

Contains 1 cpcD-like domain.

Contains 1 FAD-binding FR-type domain.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 440440Ferredoxin--NADP reductase
PRO_0000167634

Regions

Domain17 – 7559CpcD-like
Domain155 – 279125FAD-binding FR-type
Nucleotide binding214 – 2174FAD By similarity
Nucleotide binding235 – 2373FAD By similarity
Nucleotide binding253 – 2553FAD By similarity
Nucleotide binding330 – 3312NADP By similarity
Nucleotide binding360 – 3612NADP By similarity
Nucleotide binding370 – 3745NADP By similarity
Nucleotide binding399 – 4002NADP By similarity

Sites

Binding site2171NADP By similarity
Binding site2371NADP By similarity
Binding site2411FAD By similarity
Binding site2941FAD By similarity
Binding site2941NADP; via amide nitrogen By similarity
Binding site4381NADP By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q44549-1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 660BAA2DCF59BBB6

FASTA44048,826
        10         20         30         40         50         60 
MSNQGAFEGA ANVESGSRVF VYEVVGMRQN EETDQTNYPI RKSGSVFIRV PYNRMNQEMQ 

        70         80         90        100        110        120 
RITRLGGKIV SIQTVSALQQ LNGKTTIATV TDASSETAKS EGNGKATPVK TDSGAKGFAK 

       130        140        150        160        170        180 
PPAEEQLKKK DNKGNTMTQA KAKHADVPVN LYRPNAPFIG KVISNEPLVK EGGIGIVQHI 

       190        200        210        220        230        240 
KFDLTGGNLK YIEGQSIGII PPGVDKNGKP EKLRLYSIAS TRHGDDVDDK TISLCVRQLE 

       250        260        270        280        290        300 
YKHPETGETV YGVCSTYLTH IEPGSEVKIT GPVGKEMLLP DDPEANVIML ATGTGIAPMR 

       310        320        330        340        350        360 
TYLWRMFKDA ERAANPEYQF KGFSWLVFGV PTTPNILYKE ELEEIQQKYP DNFRLTYAIS 

       370        380        390        400        410        420 
REQKNPQGGR MYIQDRVAEH ADELWQLIKN EKTHTYICGL RGMEEGIDAA LSAAAAKEGV 

       430        440 
TWSDYQKDLK KAGRWHVETY

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References

« Hide 'large scale' references
[1]"Cloning and molecular characterization of the petH gene in the cyanobacterium Anabaena variabilis ATCC 29413."
Mannan R.M., Matthijs H.C.P., Pakrasi H.B.
Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Complete sequence of Anabaena variabilis ATCC 29413."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

L26346 Genomic DNA. Translation: AAA91046.1.
CP000117 Genomic DNA. Translation: ABA20406.1.
RefSeqYP_321301.1.

3D structure databases

HSSPHSSP built from PDB template 1QUE based on UniProtKB P21890.
SMRQ44549. Positions 146-440.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ44549.

Genome annotation databases

GeneID3680507.
GenomeReviewsGene locus Ava_0782 in contig CP000117_GR.
KEGGava:Ava_0782.
NMPDRfig|240292.3.peg.2575.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ44549.
OMAGRMYIQD.

Enzyme and pathway databases

BioCycAVAR240292:AVA_0782-MON.

Family and domain databases

InterProIPR017927. Fd_Rdtase_FAD-bd.
IPR001709. Flavoprot_Pyr_Nucl_cyt_Rdtase.
IPR012146. Frd-NADP+_RD.
IPR015701. FRD_Red.
IPR001433. OxRdtase_FAD/NAD_bd.
IPR008213. Phycobilisome_lnk_CpcD-like.
[Graphical view]
PANTHERPTHR19384:SF1. FRD_Red. 1 hit.
PfamPF01383. CpcD. 1 hit.
PF00175. NAD_binding_1. 1 hit.
[Graphical view]
PIRSFPIRSF000361. Frd-NADP+_RD. 1 hit.
PRINTSPR00371. FPNCR.
PROSITEPS51441. CPCD_LIKE. 1 hit.
PS51384. FAD_FR. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameFENR_ANAVT
AccessionPrimary (citable) accession number: Q44549
Secondary accession number(s): Q3MF30
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 3, 2009
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents