Q44538 (MODC2_AZOVI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Molybdenum import ATP-binding protein ModC 2
EC=3.6.3.29

Gene names

Name:

modC2

Organism

Azotobacter vinelandii

Taxonomic identifier

354 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Azotobacter group › Azotobacter

Protein attributes

Sequence length	358 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system By similarity.
Catalytic activity	ATP + H2O + molybdate(Out) = ADP + phosphate + molybdate(In).
Subunit structure	The complex is composed of two ATP-binding proteins (ModC), two transmembrane proteins (ModB) and a solute-binding protein (ModA) Potential.
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity.
Sequence similarities	Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. [View classification] Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Ligand	ATP-binding Molybdenum Nucleotide-binding
Molecular function	Hydrolase
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	ATP-binding cassette (ABC) transporter complex Inferred from electronic annotation. Source: InterPro plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW molybdate transmembrane-transporting ATPase activity Inferred from electronic annotation. Source: EC molybdenum ion transmembrane transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 358	358	Molybdenum import ATP-binding protein ModC 2		PRO_0000092529
Regions
	Domain	1 – 234	234	ABC transporter
	Nucleotide binding	35 – 42	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q44538 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 8117314F6B29BADD	FASTA	358	39,648
	10 20 30 40 50 60 MPEQGIEAQL RLQRGAFRLD AHLQLPANGI SVLLGRSGSG KTTLLRAIAG LERAEGFLQV 70 80 90 100 110 120 GGQLWQDATC FRPPHQRSLG YVRQASELLP HLDVRANLEF GYRRIPRARR RLGLDEVIAL 130 140 150 160 170 180 FGLEDLLDQR AEWLPNGPRQ RVAIACALLT SPDLLLLDAP LICLDRHSRA QILPALEQLR 190 200 210 220 230 240 GQLRIPLLYV THSQDEVTRL ADHLILLDKG KTFASGPPGR LLSDPRLPLN HPDEAAVVLI 250 260 270 280 290 300 GQVEHHDPHY RLSTVRVPGG TLSVSLSRLP PGAETRVRIF ARDVSLSLDP PHNSSILNIL 310 320 330 340 350 RVRIADLFHE QDSARVMVRL DLDSACILAR ITRLSADRLG LAPGLQVYAQ IKSVALME

References

[1]

"Physical and genetic map of the major nif gene cluster from Azotobacter vinelandii." Jacobson M.R., Brigle K.E., Bennett L.T., Setterquist R.A., Wilson M.S., Cash V.L., Beynon J., Newton W.E., Dean D.R. J. Bacteriol. 171:1017-1027(1989) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	M20568 Genomic DNA. Translation: AAA64722.1.
3D structure databases
ProteinModelPortal	Q44538.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR003439. ABC_transporter-like. IPR015852. ABC_transpr_ModC. IPR008995. Mo/tungstate-bd_C_term_dom. IPR011868. ModC_ABC_ATP-bd. IPR005116. Transp-assoc_OB_typ1. [Graphical view]
Pfam	PF00005. ABC_tran. 1 hit. PF03459. TOBE. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF50331. MOP_like. 1 hit.
TIGRFAMs	TIGR02142. modC_ABC. 1 hit.
PROSITE	PS00211. ABC_TRANSPORTER_1. False negative. PS50893. ABC_TRANSPORTER_2. 1 hit. PS51241. MODC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MODC2_AZOVI

Accession

Primary (citable) accession number: Q44538

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 2005
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program