Q44244 (Q44244_9PSEU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
N-acylamino acid racemase EMBL BAA06400.1

Gene names

Name:

Aaar EMBL BAA06400.1

Organism

Amycolatopsis sp. EMBL BAA06400.1

Taxonomic identifier

37632 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Amycolatopsis

Protein attributes

Sequence length	368 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Magnesium PDB 1SJA PDB 1SJB PDB 1SJC Metal-binding SAAS SAAS013342 PDB 1SJA PDB 1SJB PDB 1SJC
Technical term	3D-structure PDB 1SJA PDB 1SJD PDB 1SJB PDB 1SJC
Gene Ontology (GO)
Molecular function	catalytic activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	189	1	Magnesium PDB 1SJA PDB 1SJB PDB 1SJC
	Metal binding	191	1	Magnesium PDB 1SJB
	Metal binding	214	1	Magnesium PDB 1SJA PDB 1SJB PDB 1SJC
	Metal binding	239	1	Magnesium PDB 1SJA PDB 1SJB PDB 1SJC

Sequences

	Sequence		Length	Mass (Da)
	Q44244 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 623A27548DA0E8C4	FASTA	368	39,406
	10 20 30 40 50 60 MKLSGVELRR VQMPLVAPFR TSFGTQSVRE LLLLRAVTPA GEGWGECVTM AGPLYSSEYN 70 80 90 100 110 120 DGAEHVLRHY LIPALLAAED ITAAKVTPLL AKFKGHRMAK GALEMAVLDA ELRAHERSFA 130 140 150 160 170 180 AELGSVRDSV PCGVSVGIMD TIPQLLDVVG GYLDEGYVRI KLKIEPGWDV EPVRAVRERF 190 200 210 220 230 240 GDDVLLQVDA NTAYTLGDAP QLARLDPFGL LLIEQPLEEE DVLGHAELAR RIQTPICLDE 250 260 270 280 290 300 SIVSARAAAD AIKLGAVQIV NIKPGRVGGY LEARRVHDVC AAHGIPVWCG GMIETGLGRA 310 320 330 340 350 360 ANVALASLPN FTLPGDTSAS DRFYKTDITE PFVLSGGHLP VPTGPGLGVA PIPELLDEVT TAKVWIGS

References

[1]	"Cloning, DNA sequencing and heterologous expression of the gene for thermostable N-acylamino acid racemase from Amycolatopsis sp. TS-1-60 in Escherichia coli." Tokuyama S., Hatano K. Appl. Microbiol. Biotechnol. 42:884-889(1995) [PubMed: 7766089] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: TS-1-60 EMBL BAA06400.1.
[2]	"Evolution of enzymatic activity in the enolase superfamily: structural studies of the promiscuous o-succinylbenzoate synthase from Amycolatopsis." Thoden J.B., Taylor Ringia E.A., Garrett J.B., Gerlt J.A., Holden H.M., Rayment I. Biochemistry 43:5716-5727(2004) [PubMed: 15134446] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.87 ANGSTROMS) IN COMPLEX WITH MAGNESIUM.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

D30738 Genomic DNA. Translation: BAA06400.1.

PIR

I39598.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1SJA	X-ray	2.30	A/B/C/D	1-368	[»]
1SJB	X-ray	2.20	A/B/C/D	1-368	[»]
1SJC	X-ray	2.10	A/B/C/D	1-368	[»]
1SJD	X-ray	1.87	A/B/C/D	1-368	[»]

ProteinModelPortal

Q44244.

SMR

Q44244. Positions 1-368.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR013342. Mandelate_racemase_C.
IPR013341. Mandelate_racemase_N.
IPR001354. MR_MLE.
IPR010197. OSB_synthase_lowGC-bac/arc.
[Graphical view]

PANTHER

PTHR13794:SF8. MenC_lowGC_arc. 1 hit.
PTHR13794. MR_MLE. 1 hit.

Pfam

PF01188. MR_MLE. 1 hit.
PF02746. MR_MLE_N. 1 hit.
[Graphical view]

SMART

SM00922. MR_MLE. 1 hit.
[Graphical view]

TIGRFAMs

TIGR01928. MenC_lowGC/arch. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q44244_9PSEU

Accession

Primary (citable) accession number: Q44244

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	May 31, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)