Q44004 (SBNA_RALME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative siderophore biosynthesis protein SbnA

Gene names

Name:	sbnA
Ordered Locus Names:	Rmet_1117

Organism

Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839) [Complete proteome] [HAMAP]

Taxonomic identifier

266264 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Cupriavidus

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probable pyridoxal phosphate-dependent enzyme that may be involved in siderophore biosynthesis By similarity.
Cofactor	Pyridoxal phosphate By similarity.
Sequence similarities	Belongs to the cysteine synthase/cystathionine beta-synthase family.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro
Molecular function	catalytic activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 341	341	Putative siderophore biosynthesis protein SbnA		PRO_0000167105
Regions
	Region	181 – 185	5	Pyridoxal phosphate binding By similarity
Sites
	Binding site	73	1	Pyridoxal phosphate By similarity
	Binding site	268	1	Pyridoxal phosphate By similarity
Amino acid modifications
	Modified residue	43	1	N6-(pyridoxal phosphate)lysine By similarity
Experimental info
	Sequence conflict	17 – 18	2	QL → HV in CAA66130. Ref.1
	Sequence conflict	168 – 169	2	QL → HV in CAA66130. Ref.1
	Sequence conflict	181	1	S → T in CAA66130. Ref.1
	Sequence conflict	209 – 265	57	GSVLF…EGIFA → FPCCSANRRKRASCRALAPR RAGIAVPGRDRRSDPYRRLH RRHGAGACWRRRHLR in CAA66130. Ref.1
	Sequence conflict	320	1	R → T in CAA66130. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q44004 [UniParc]. Last modified July 11, 2006. Version 2. Checksum: 46EE65F2BBCD5F88	FASTA	341	36,838
	10 20 30 40 50 60 MVCNSIIESI GNTPLVQLRR LFGRADAEVF AKLELLNPAG SVKDRPARYI VEKGLTEGAI 70 80 90 100 110 120 GPHSHVIESS SGNLAIALAM ICGLKGLRFT AVVDPKISPT NLKILRCYGA GIEQVTAKDS 130 140 150 160 170 180 QGGYLETRIE RVRQMLREQR DAIWINQYAN PLNWESHYYG EAAEILAQLA QPADVLVLGV 190 200 210 220 230 240 STSGTVHGIA RRLRKAWPSM RVVGVDAVGS VLFGQPSQAR ELPGIGASRV PELLCRDEID 250 260 270 280 290 300 EVIHIDDYTA ATACRRLLAR EGIFAGGSSG AVVAAIEQVL HATPVSHRPL RILTLFPDRG 310 320 330 340 ERYLDTVYDD AWLARIAARR AVPNLAALPT VASLIPAGVS A

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Siderophore-mediated iron uptake in Alcaligenes eutrophus CH34 and identification of aleB encoding the ferric iron-alcaligin E receptor." Gilis A., Khan M.A., Cornelis P., Meyer J.M., Mergeay M., van der Lelie D. J. Bacteriol. 178:5499-5507(1996) [PubMed: 8808942] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete sequence of the chromosome of Ralstonia metallidurans CH34." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Martinez M., Goltsman E., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Mergeay M., Benotmane M.A., Vallaeys T., Michaux A., Monchy S., Dunn J., McCorkle S., Taghavi S., van der Lelie D., Richardson P. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CH34 / ATCC 43123 / DSM 2839.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X97499 Genomic DNA. Translation: CAA66130.1. CP000352 Genomic DNA. Translation: ABF08003.1.
RefSeq	YP_583272.1. NC_007973.1.
3D structure databases
ProteinModelPortal	Q44004.
ModBase	Search...
Protein-protein interaction databases
STRING	Q44004.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4037915.
GenomeReviews	Gene locus Rmet_1117 in contig CP000352_GR.
KEGG	rme:Rmet_1117.
PATRIC	20286814. VBIRalMet4734_1514.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0031.
HOGENOM	HBG748215.
OMA	GYLETRI.
PhylomeDB	Q44004.
ProtClustDB	CLSK884408.
Enzyme and pathway databases
BioCyc	RMET266264:RMET_1117-MONOMER.
Family and domain databases
InterPro	IPR001216. Cys_synth_BS. IPR023927. DiNH2opropionate_SbnA. IPR001926. PyrdxlP-dep_enz_bsu. [Graphical view]
KO	K01738.
Pfam	PF00291. PALP. 1 hit. [Graphical view]
SUPFAM	SSF53686. PyrdxlP-dep_enz_bsu. 1 hit.
TIGRFAMs	TIGR03945. PLP_SbnA_fam. 1 hit.
PROSITE	PS00901. CYS_SYNTHASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SBNA_RALME

Accession

Primary (citable) accession number: Q44004
Secondary accession number(s): Q1LPC3

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	July 11, 2006
Last modified:	January 25, 2012
This is version 78 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program