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Q43973 (PCAI_ACIAD) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-oxoadipate CoA-transferase subunit A

EC=2.8.3.6
Alternative name(s):
Beta-ketoadipate:succinyl-CoA transferase subunit A
Gene names
Name:pcaI
Ordered Locus Names:ACIAD1704
AND
Name:catI
Ordered Locus Names:ACIAD1448
OrganismAcinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) [Complete proteome] [HAMAP]
Taxonomic identifier62977 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacter

Protein attributes

Sequence length228 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA.

Pathway

Aromatic compound metabolism; beta-ketoadipate pathway; acetyl-CoA and succinyl-CoA from 3-oxoadipate: step 1/2.

Subunit structure

Heterodimer By similarity.

Sequence similarities

Belongs to the 3-oxoacid CoA-transferase subunit A family.

Ontologies

Keywords
   Biological processAromatic hydrocarbons catabolism
   Molecular functionTransferase
   Technical termComplete proteome
Direct protein sequencing
Gene Ontology (GO)
   Biological_processbeta-ketoadipate pathway

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_function3-oxoadipate CoA-transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2282283-oxoadipate CoA-transferase subunit A
PRO_0000157906

Regions

Region25 – 317CoA-binding Potential

Sequences

Sequence LengthMass (Da)Tools
Q43973 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 157C8270BBA46FC1

FASTA22824,074
        10         20         30         40         50         60 
MIDKSAATLT EALSQIHDGA TILIGGFGTA GQPAELIDGL IELGRKNLTI VSNNAGNGDY 

        70         80         90        100        110        120 
GLAKLLKTGA VKKIICSFPR QADSYVFDEL YRAGKIELEI VPQGNLACRI QAAGMGLGPI 

       130        140        150        160        170        180 
YTPTGFGTLL AEGKPTLNFD GKDYVLENPI KADFALIKAY KGDRWGNLVY RKSARNFGPI 

       190        200        210        220 
MAMAANVTIA QVSEVVALGE LDPENVVTPG IFVQHVVPVQ STPASAAP 

« Hide

References

« Hide 'large scale' references
[1]"Contrasting patterns of evolutionary divergence within the Acinetobacter calcoaceticus pca operon."
Kowalchuk G.A., Hartnett G.B., Benson A., Houghton J.E., Ngai K.-L., Ornston L.N.
Gene 146:23-30(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-34 (PCAI).
[2]"Unusual G + C content and codon usage in catIJF, a segment of the ben-cat supra-operonic cluster in the Acinetobacter calcoaceticus chromosome."
Shanley M.S., Harrison A., Parales R.E., Kowalchuk G., Mitchell D.J., Ornston L.N.
Gene 138:59-65(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (CATI).
[3]"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium."
Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C.
Nucleic Acids Res. 32:5766-5779(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (PCAI AND CATI).
Strain: ATCC 33305 / BD413 / ADP1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L05770 Genomic DNA. Translation: AAC37146.1.
AF009224 Genomic DNA. Translation: AAC46432.1.
CR543861 Genomic DNA. Translation: CAG68546.1.
CR543861 Genomic DNA. Translation: CAG68311.1.
PIRA44570.
RefSeqYP_046133.1. NC_005966.1.
YP_046368.1. NC_005966.1.

3D structure databases

ProteinModelPortalQ43973.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING62977.ACIAD1704.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAG68311; CAG68311; ACIAD1448.
CAG68546; CAG68546; ACIAD1704.
GeneID2879438.
2879924.
KEGGaci:ACIAD1448.
aci:ACIAD1704.
PATRIC20740706. VBIAciSp98416_1305.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1788.
HOGENOMHOG000221244.
KOK01031.
OMANKAGRNF.
OrthoDBEOG6HMXJG.
ProtClustDBCLSK751191.

Enzyme and pathway databases

BioCycASP62977:GJVV-1375-MONOMER.
ASP62977:GJVV-1616-MONOMER.
UniPathwayUPA00157; UER00262.

Family and domain databases

InterProIPR012792. 3-oxoacid_CoA-transf_A.
IPR004165. CoA_trans_fam_I.
IPR004163. CoA_transf_BS.
[Graphical view]
PANTHERPTHR13707. PTHR13707. 1 hit.
PfamPF01144. CoA_trans. 1 hit.
[Graphical view]
SMARTSM00882. CoA_trans. 1 hit.
[Graphical view]
TIGRFAMsTIGR02429. pcaI_scoA_fam. 1 hit.
PROSITEPS01273. COA_TRANSF_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePCAI_ACIAD
AccessionPrimary (citable) accession number: Q43973
Secondary accession number(s): Q43933
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: January 22, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways