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Protein

Probable sucrose-phosphate synthase

Gene

SPS

Organism
Solanum tuberosum (Potato)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP-glucose and fructose- 6-phosphate. Involved in the regulation of carbon partitioning in the leaves of plants. May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf. Plays a role for sucrose availability that is essential for plant growth and fiber elongation (By similarity).By similarity

Catalytic activityi

UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6(F)-phosphate.

Enzyme regulationi

Activity is regulated by phosphorylation and moderated by concentration of metabolites and light.By similarity

Pathwayi: sucrose biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes sucrose from D-fructose 6-phosphate and UDP-alpha-D-glucose.
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Probable sucrose-phosphate synthase (SPS)
  2. no protein annotated in this organism
This subpathway is part of the pathway sucrose biosynthesis, which is itself part of Glycan biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes sucrose from D-fructose 6-phosphate and UDP-alpha-D-glucose, the pathway sucrose biosynthesis and in Glycan biosynthesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00371; UER00545.

Protein family/group databases

CAZyiGT4. Glycosyltransferase Family 4.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable sucrose-phosphate synthase (EC:2.4.1.14)
Alternative name(s):
UDP-glucose-fructose-phosphate glucosyltransferase
Gene namesi
Name:SPS
OrganismiSolanum tuberosum (Potato)
Taxonomic identifieri4113 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum
Proteomesi
  • UP000011115 Componenti: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002046731 – 1053Probable sucrose-phosphate synthaseAdd BLAST1053

Interactioni

Subunit structurei

Homodimer or homotetramer.By similarity

Protein-protein interaction databases

STRINGi4113.PGSC0003DMT400071807.

Structurei

3D structure databases

ProteinModelPortaliQ43845.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family.Curated

Phylogenomic databases

eggNOGiKOG0853. Eukaryota.
COG0438. LUCA.
InParanoidiQ43845.

Family and domain databases

InterProiIPR001296. Glyco_trans_1.
IPR006380. SPP_N.
IPR000368. Sucrose_synth.
IPR012819. SucrsPsyn_pln.
[Graphical view]
PfamiPF00534. Glycos_transf_1. 1 hit.
PF05116. S6PP. 1 hit.
PF00862. Sucrose_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02468. sucrsPsyn_pln. 1 hit.

Sequencei

Sequence statusi: Complete.

Q43845-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGNDWINSY LEAILDVGPG LDDKKSSLLL RERGRFSPTR YFVEEVITGF
60 70 80 90 100
DETDLHRSWI RAQATRSPQR RNTRLENMCW RIWNLARQKK QLEGEQAQWM
110 120 130 140 150
AKRRQERERG RREAVADMSE DLSEGEKGDI VADMSSHGES TRGRLPRISS
160 170 180 190 200
VETMEAWVSQ QRGKKLYIVL ISLHGLIRGE NMELGRDSDT GGQVKYVVEL
210 220 230 240 250
ARALGSMPGV YRVDLLTRQV SSPEVDWSYG EPTELAPIST DGLMTEMGES
260 270 280 290 300
SGAYIIRIPF GPREKYIPKE QLWPYIPEFV DGALNHIIQM SKVLGEQIGS
310 320 330 340 350
GYPVWPVAIH GHYADAGDSA ALLSGALNVP MLFTGHSLGR DKLEQLLAQG
360 370 380 390 400
RKSKDEINST YKIMRRIEAE ELTLDASEIV ITSTRQEIDE QWRLYDGFDP
410 420 430 440 450
ILERKLRARI KRNVSCYGRF MPRMAVIPPG MEFHHIVPHE GDMDGETEGS
460 470 480 490 500
EDGKTPDPPI WAEIMRFFSN PRKPMILALA RPDPKKNLTT LVKAFGECRP
510 520 530 540 550
LRDLANLTLI MGNRDNIDEM SSTNSALLLS ILKMIDKYDL YGQVAYPKHH
560 570 580 590 600
KQSDVPDIYR LAAKTKGVFI NPAFIEPFGL TLIEAAAYGL PMVATKNGGP
610 620 630 640 650
VDIHRVLDNG LLVDPHDQQA IADALLKLVA DKQLWAKCRA NGLKNIHLFS
660 670 680 690 700
WPEHCKTYLS RIASCKPRQP RWLRSIDDDD ENSETDSPSD SLRDIHDISL
710 720 730 740 750
NLRFSLDGEK NDNKENADNT LDPEVRRSKL ENAVLSLSKG ALKSTSKSWS
760 770 780 790 800
SDKADQNPGA GKFPAIRRRR HIFVIAVDCD ASSGLSGSVK KIFEAVEKER
810 820 830 840 850
AEGSIGFILA TSFNISEVQS FLLSEGMNPT DFDAYICNSG GDLYYSSFHS
860 870 880 890 900
EQNPFVVDLY YHSHIEYRWG GEGLRKTLVR WAASIIDKNG ENGDHIVVED
910 920 930 940 950
EDNSADYCYT FKVCKPGTVP PSKELRKVMR IQALRCHAVY CQNGSRINVI
960 970 980 990 1000
PVLASRSQAL RYLYLRWGMD LSKLVVFVGE SGDTDYEGLI GGLRKAVIMK
1010 1020 1030 1040 1050
GLCTNASSLI HGNRNYPLSD VLPFDSPNVI QADEECSSTE IRCLLEKLAV

LKG
Length:1,053
Mass (Da):118,292
Last modified:November 1, 1996 - v1
Checksum:iD6C933798567B20A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73477 mRNA. Translation: CAA51872.1.
PIRiS34172.
UniGeneiStu.18907.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73477 mRNA. Translation: CAA51872.1.
PIRiS34172.
UniGeneiStu.18907.

3D structure databases

ProteinModelPortaliQ43845.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4113.PGSC0003DMT400071807.

Protein family/group databases

CAZyiGT4. Glycosyltransferase Family 4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0853. Eukaryota.
COG0438. LUCA.
InParanoidiQ43845.

Enzyme and pathway databases

UniPathwayiUPA00371; UER00545.

Family and domain databases

InterProiIPR001296. Glyco_trans_1.
IPR006380. SPP_N.
IPR000368. Sucrose_synth.
IPR012819. SucrsPsyn_pln.
[Graphical view]
PfamiPF00534. Glycos_transf_1. 1 hit.
PF05116. S6PP. 1 hit.
PF00862. Sucrose_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02468. sucrsPsyn_pln. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSPSA_SOLTU
AccessioniPrimary (citable) accession number: Q43845
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: April 13, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.