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Q43776

- SYK_SOLLC

UniProt

Q43776 - SYK_SOLLC

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Protein
Lysine--tRNA ligase
Gene
LYSRS
Organism
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. lysine-tRNA ligase activity Source: UniProtKB-EC
  3. nucleic acid binding Source: InterPro

GO - Biological processi

  1. lysyl-tRNA aminoacylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Lysine--tRNA ligase (EC:6.1.1.6)
Alternative name(s):
Lysyl-tRNA synthetase
Short name:
LysRS
Gene namesi
Name:LYSRS
OrganismiSolanum lycopersicum (Tomato) (Lycopersicon esculentum)
Taxonomic identifieri4081 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanumLycopersicon
ProteomesiUP000004994: Unplaced

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 588588Lysine--tRNA ligaseUniRule annotation
PRO_0000152769Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ43776.
SMRiQ43776. Positions 52-588.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK04567.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00252. Lys_tRNA_synth_class2.
InterProiIPR004364. aa-tRNA-synt_II.
IPR018150. aa-tRNA-synt_II-like.
IPR006195. aa-tRNA-synth_II.
IPR002313. Lys-tRNA-ligase_II.
IPR018149. Lys-tRNA-synth_II_C.
IPR012340. NA-bd_OB-fold.
IPR004365. NA-bd_OB_tRNA.
[Graphical view]
PANTHERiPTHR22594. PTHR22594. 1 hit.
PfamiPF00152. tRNA-synt_2. 1 hit.
PF01336. tRNA_anti-codon. 1 hit.
[Graphical view]
PRINTSiPR00982. TRNASYNTHLYS.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00499. lysS_bact. 1 hit.
PROSITEiPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q43776-1 [UniParc]FASTAAdd to Basket

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MDSSVSTEPL SKNALKREKK AKEKEQLEQE KKAAAVAKRQ MEQHNLPEND    50
DLDPTQYLAN RLRNIESLRE SGINPYPHKF FITMSIPEFI SRYAHLNTGE 100
FPEDIDMSLA GRVISKRASS SKLYFYELLG GGARVQVLAS ARDSDVDAVQ 150
FSNYQSGVKR GDIIGVRGYP GKSKRGELSI FAKPFIVLAP CLHMLPRRLT 200
SSIVDETRTQ NFQGITAYDT WTPGDLRNPE SYVLRDQETR YRQRYLDLMM 250
NPEVRALFRT RARIISYIRS FLDNLEFLEV ETPSMNLTAG GASARPFITH 300
HNELDTELLI RVSPELYLKK LVVGGFDRVY ELGKHFRNEG MDLTHSPEFT 350
MCELYMAYAD YNDLMDLTEQ LLSGMVKDLT GSYKIRYHAN GLDNEPIEID 400
FTPPFRKIDM LSELEKVANI SIPRDLSSES ANKHLVDVCE KFDVKCPPPH 450
TTTRLLDKLV GHFIEVNCIN PTFIINHPEI MSPLAKSRRS EPGLTERFNL 500
FVNRRELCDA YTELNDPTAQ RERFAEQLKD RQLGDDEAMD LDESFITALE 550
YGLPPTGGLG MGIDRLTMLL TDSQNVKEVI LFPAMRLQ 588
Length:588
Mass (Da):67,116
Last modified:November 1, 1996 - v1
Checksum:i66590227238C20CF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X94451 mRNA. Translation: CAA64223.1.
PIRiT07085.
RefSeqiNP_001234285.1. NM_001247356.1.
UniGeneiLes.3641.

Genome annotation databases

GeneIDi778357.
KEGGisly:778357.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X94451 mRNA. Translation: CAA64223.1 .
PIRi T07085.
RefSeqi NP_001234285.1. NM_001247356.1.
UniGenei Les.3641.

3D structure databases

ProteinModelPortali Q43776.
SMRi Q43776. Positions 52-588.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 778357.
KEGGi sly:778357.

Phylogenomic databases

KOi K04567.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
HAMAPi MF_00252. Lys_tRNA_synth_class2.
InterProi IPR004364. aa-tRNA-synt_II.
IPR018150. aa-tRNA-synt_II-like.
IPR006195. aa-tRNA-synth_II.
IPR002313. Lys-tRNA-ligase_II.
IPR018149. Lys-tRNA-synth_II_C.
IPR012340. NA-bd_OB-fold.
IPR004365. NA-bd_OB_tRNA.
[Graphical view ]
PANTHERi PTHR22594. PTHR22594. 1 hit.
Pfami PF00152. tRNA-synt_2. 1 hit.
PF01336. tRNA_anti-codon. 1 hit.
[Graphical view ]
PRINTSi PR00982. TRNASYNTHLYS.
SUPFAMi SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00499. lysS_bact. 1 hit.
PROSITEi PS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A root-specific iron-regulated gene of tomato encodes a lysyl-tRNA-synthetase-like protein."
    Giritch A., Herbik A., Balzer H.-J., Ganal M., Stephan U.W., Baumlein H.
    Eur. J. Biochem. 244:310-317(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Bonner Beste.
    Tissue: Root.

Entry informationi

Entry nameiSYK_SOLLC
AccessioniPrimary (citable) accession number: Q43776
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: September 3, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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