Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Lysine--tRNA ligase

Gene

LYSRS

Organism
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Lysine--tRNA ligase (EC:6.1.1.6)
Alternative name(s):
Lysyl-tRNA synthetase
Short name:
LysRS
Gene namesi
Name:LYSRS
OrganismiSolanum lycopersicum (Tomato) (Lycopersicon esculentum)
Taxonomic identifieri4081 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanumLycopersicon
Proteomesi

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001527691 – 588Lysine--tRNA ligaseAdd BLAST588

Proteomic databases

PaxDbiQ43776

Expressioni

Gene expression databases

ExpressionAtlasiQ43776 baseline

Interactioni

Protein-protein interaction databases

STRINGi4081.Solyc10g076610.1.1

Structurei

3D structure databases

ProteinModelPortaliQ43776
SMRiQ43776
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1885 Eukaryota
COG1190 LUCA
InParanoidiQ43776
KOiK04567

Family and domain databases

CDDicd00775 LysRS_core, 1 hit
HAMAPiMF_00252 Lys_tRNA_synth_class2, 1 hit
InterProiView protein in InterPro
IPR004364 aa-tRNA-synt_II
IPR006195 aa-tRNA-synth_II
IPR002313 Lys-tRNA-ligase_II
IPR034762 Lys-tRNA-ligase_II_bac/euk
IPR018149 Lys-tRNA-synth_II_C
IPR012340 NA-bd_OB-fold
IPR004365 NA-bd_OB_tRNA
PfamiView protein in Pfam
PF00152 tRNA-synt_2, 1 hit
PF01336 tRNA_anti-codon, 1 hit
PIRSFiPIRSF039101 LysRS2, 1 hit
PRINTSiPR00982 TRNASYNTHLYS
SUPFAMiSSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00499 lysS_bact, 1 hit
PROSITEiView protein in PROSITE
PS50862 AA_TRNA_LIGASE_II, 1 hit

Sequencei

Sequence statusi: Complete.

Q43776-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSSVSTEPL SKNALKREKK AKEKEQLEQE KKAAAVAKRQ MEQHNLPEND
60 70 80 90 100
DLDPTQYLAN RLRNIESLRE SGINPYPHKF FITMSIPEFI SRYAHLNTGE
110 120 130 140 150
FPEDIDMSLA GRVISKRASS SKLYFYELLG GGARVQVLAS ARDSDVDAVQ
160 170 180 190 200
FSNYQSGVKR GDIIGVRGYP GKSKRGELSI FAKPFIVLAP CLHMLPRRLT
210 220 230 240 250
SSIVDETRTQ NFQGITAYDT WTPGDLRNPE SYVLRDQETR YRQRYLDLMM
260 270 280 290 300
NPEVRALFRT RARIISYIRS FLDNLEFLEV ETPSMNLTAG GASARPFITH
310 320 330 340 350
HNELDTELLI RVSPELYLKK LVVGGFDRVY ELGKHFRNEG MDLTHSPEFT
360 370 380 390 400
MCELYMAYAD YNDLMDLTEQ LLSGMVKDLT GSYKIRYHAN GLDNEPIEID
410 420 430 440 450
FTPPFRKIDM LSELEKVANI SIPRDLSSES ANKHLVDVCE KFDVKCPPPH
460 470 480 490 500
TTTRLLDKLV GHFIEVNCIN PTFIINHPEI MSPLAKSRRS EPGLTERFNL
510 520 530 540 550
FVNRRELCDA YTELNDPTAQ RERFAEQLKD RQLGDDEAMD LDESFITALE
560 570 580
YGLPPTGGLG MGIDRLTMLL TDSQNVKEVI LFPAMRLQ
Length:588
Mass (Da):67,116
Last modified:November 1, 1996 - v1
Checksum:i66590227238C20CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X94451 mRNA Translation: CAA64223.1
PIRiT07085
RefSeqiNP_001234285.1, NM_001247356.1
UniGeneiLes.3641

Genome annotation databases

GeneIDi778357
KEGGisly:778357

Entry informationi

Entry nameiSYK_SOLLC
AccessioniPrimary (citable) accession number: Q43776
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health