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Protein

UTP--glucose-1-phosphate uridylyltransferase

Gene
N/A
Organism
Hordeum vulgare (Barley)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Plays a central role as a glucosyl donor in cellular metabolic pathways.

Catalytic activityi

UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei103UTPBy similarity1
Binding sitei166UTPBy similarity1
Binding sitei195UTP; via amide nitrogenBy similarity1
Binding sitei196SubstrateBy similarity1
Binding sitei226UTPBy similarity1
Binding sitei364UTPBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase

Enzyme and pathway databases

BRENDAi2.7.7.9 2687
SABIO-RKQ43772

Names & Taxonomyi

Protein namesi
Recommended name:
UTP--glucose-1-phosphate uridylyltransferase (EC:2.7.7.9)
Alternative name(s):
UDP-glucose pyrophosphorylase
Short name:
UDPGP
Short name:
UGPase
OrganismiHordeum vulgare (Barley)
Taxonomic identifieri4513 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaeTriticodaeTriticeaeHordeinaeHordeum

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001857591 – 473UTP--glucose-1-phosphate uridylyltransferaseAdd BLAST473

Proteomic databases

PRIDEiQ43772

Expressioni

Gene expression databases

ExpressionAtlasiQ43772 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ43772
SMRiQ43772
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni89 – 92UTP bindingBy similarity4
Regioni91 – 92Substrate bindingBy similarity2
Regioni224 – 226Substrate bindingBy similarity3

Sequence similaritiesi

Belongs to the UDPGP type 1 family.Curated

Phylogenomic databases

eggNOGiKOG2638 Eukaryota
COG4284 LUCA

Family and domain databases

CDDicd00897 UGPase_euk, 1 hit
Gene3Di3.90.550.10, 1 hit
InterProiView protein in InterPro
IPR029044 Nucleotide-diphossugar_trans
IPR002618 UDPGP_fam
IPR016267 UDPGP_trans
PfamiView protein in Pfam
PF01704 UDPGP, 1 hit
PIRSFiPIRSF000806 UDPGP, 1 hit
SUPFAMiSSF53448 SSF53448, 1 hit

Sequencei

Sequence statusi: Complete.

Q43772-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAAAVAADS KIDGLRDAVA KLGEISENEK AGFISLVSRY LSGEAEQIEW
60 70 80 90 100
SKIQTPTDEV VVPYDTLAPP PEDLDAMKAL LDKLVVLKLN GGLGTTMGCT
110 120 130 140 150
GPKSVIEVRN GFTFLDLIVI QIESLNKKYG CSVPLLLMNS FNTHDDTQKI
160 170 180 190 200
VEKYSNSNIE IHTFNQSQYP RIVTEDFLPL PSKGQTGKDG WYPPGHGDVF
210 220 230 240 250
PSLNNSGKLD TLLSQGKEYV FVANSDNLGA IVDIKILNHL IHNQNEYCME
260 270 280 290 300
VTPKTLADVK GGTLISYEGR VQLLEIAQVP DEHVDEFKSI EKFKIFNTNN
310 320 330 340 350
LWVNLKAIKR LVDAEALKME IIPNPKEVDG VKVLQLETAA GAAIRFFEKA
360 370 380 390 400
IGINVPRSRF LPVKATSDLL LVQSDLYTLV DGYVIRNPAR VKPSNPSIEL
410 420 430 440 450
GPEFKKVANF LARFKSIPSI VELDSLKVSG DVSFGSGVVL KGNVTIAAKA
460 470
GVKLEIPDGA VLENKDINGP EDI
Length:473
Mass (Da):51,644
Last modified:November 1, 1996 - v1
Checksum:i1155AA1C90E748FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X91347 mRNA Translation: CAA62689.1
PIRiJC4785

Similar proteinsi

Entry informationi

Entry nameiUGPA_HORVU
AccessioniPrimary (citable) accession number: Q43772
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

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