Peroxidase 57 precursor - Arabidopsis thaliana (Mouse-ear cress)

Contribute

Send feedback

Reviewed, UniProtKB/Swiss-Prot Q43729 (PER57_ARATH)

Last modified December 16, 2008. Version 70. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data |

Customize display

text xml rdf/xml gff fasta

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein names

Recommended name:
    Peroxidase 57
      Short name=Atperox P57
    EC=1.11.1.7
Alternative name(s):
    PRXR10
    ATP13a

Gene names

Name:	PER57
Synonyms:	P57
Ordered Locus Names:	At5g17820
ORF Names:	MVA3.18, MVA3.170

Organism

Arabidopsis thaliana (Mouse-ear cress) [Complete proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

Hide | Top

Protein attributes

Sequence length	313 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

Hide | Top

General annotation (Comments)

Function	Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Catalytic activity	Donor + H(2)O(2) = oxidized donor + 2 H(2)O.
Cofactor	Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity. Binds 2 calcium ions per subunit By similarity.
Subcellular location	SecretedBy similarity.
Tissue specificity	Mainly expressed in roots. Ref.7
Induction	Positively light-regulated during the firt stage of development. Up-regulated transiently by a cold treatment. Induced in shoots of plants subjected to a long Fe deficiency stress. Down-regulated by salicylic acid, a plant defense-related signaling molecule. Ref.8 Ref.9 Ref.10 Ref.11
Miscellaneous	There are 73 peroxidase genes in A.thaliana.
Sequence similarities	Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.

Hide | Top

Ontologies

Keywords
Biological process	Hydrogen peroxide
Cellular component	Secreted
Domain	Signal
Ligand	Calcium Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
PTM	Pyrrolidone carboxylic acid
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-KW membrane Inferred from direct assay. Source: TAIR plant-type cell wall Inferred from direct assay. Source: TAIR
Molecular function	calcium ion binding Inferred from electronic annotation. Source: UniProtKB-KW electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW peroxidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Hide | Top

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Signal peptide

1 – 22

Potential

Chain

23 – 313

291

Peroxidase 57

PRO_0000023722

Sites

Active site

Proton acceptor By similarity

Metal binding

Calcium 1 By similarity

Metal binding

Calcium 1; via carbonyl oxygen By similarity

Metal binding

Calcium 1; via carbonyl oxygen By similarity

Metal binding

Calcium 1 By similarity

Metal binding

Calcium 1 By similarity

Metal binding

185

Iron (heme axial ligand) By similarity

Metal binding

186

Calcium 2 By similarity

Metal binding

233

Calcium 2 By similarity

Metal binding

236

Calcium 2 By similarity

Metal binding

241

Calcium 2 By similarity

Binding site

155

Substrate; via carbonyl oxygen By similarity

Site

Transition state stabilizer By similarity

Amino acid modifications

Modified residue

Pyrrolidone carboxylic acid By similarity

Disulfide bond

33 ↔ 109

By similarity

Disulfide bond

66 ↔ 71

By similarity

Disulfide bond

115 ↔ 309

By similarity

Disulfide bond

192 ↔ 224

By similarity

Hide | Top

Sequences

Sequence

Length

Mass (Da)

Tools

Q43729-1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: BFD2855EC45DFF26
Show »

FASTA

313

34,098

        10         20         30         40         50         60 
MMKGAKFSSL LVLFFIFPIA FAQLRVGFYS QSCPQAETIV RNLVRQRFGV TPTVTAALLR 

        70         80         90        100        110        120 
MHFHDCFVKG CDASLLIDST NSEKTAGPNG SVREFDLIDR IKAQLEAACP STVSCADIVT 

       130        140        150        160        170        180 
LATRDSVALA GGPSYSIPTG RRDGRVSNNL DVTLPGPTIS VSGAVSLFTN KGMNTFDAVA 

       190        200        210        220        230        240 
LLGAHTVGQG NCGLFSDRIT SFQGTGRPDP SMDPALVTSL RNTCRNSATA ALDQSSPLRF 

       250        260        270        280        290        300 
DNQFFKQIRK RRGVLQVDQR LASDPQTRGI VARYANNNAF FKRQFVRAMV KMGAVDVLTG 

       310 
RNGEIRRNCR RFN

« Hide

Hide | Top

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Eleven cDNA clones from Arabidopsis thaliana encoding isoperoxidases." Capelli N., Tognolli M., Flach J., Overney S., Penel C., Greppin H., Simon P. (er) Plant Gene Register PGR96-066 Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Columbia.
[2]	"From expressed sequence tags to structure, function, evolution and expression of 28 ER-targeted Arabidopsis peroxidases." Welinder K.G., Jespersen H.M., Kjaersgaard I.V.H., Justesen A.F., Oestergaard L., Abelskov A.K., Jensen R.B., Hansen L.N., Rasmussen S.K. Submitted (JUN-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Columbia.
[3]	"Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence features of the regions of 1,044,062 bp covered by thirteen physically assigned P1 clones." Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N., Tabata S. DNA Res. 4:291-300(1997) [PubMed: 9405937] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[4]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[5]	"Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[6]	"Computational analyses and annotations of the Arabidopsis peroxidase gene family." Oestergaard L., Pedersen A.G., Jespersen H.M., Brunak S., Welinder K.G. FEBS Lett. 433:98-102(1998) [PubMed: 9738941] [Abstract] Cited for: CHARACTERIZATION. Strain: cv. Columbia.
[7]	"Toward elucidating the global gene expression patterns of developing Arabidopsis: parallel analysis of 8300 genes by a high-density oligonucleotide probe array." Zhu T., Budworth P., Han B., Brown D., Chang H.-S., Zou G., Wang X. Plant Physiol. Biochem. 39:221-242(2001) Cited for: TISSUE SPECIFICITY. Strain: cv. Columbia.
[8]	"Differential gene expression in Arabidopsis monitored using cDNA arrays." Desprez T., Amselem J., Caboche M., Hoefte H. Plant J. 14:643-652(1998) [PubMed: 9675907] [Abstract] Cited for: INDUCTION. Strain: cv. Columbia.
[9]	"Coordinated plant defense responses in Arabidopsis revealed by microarray analysis." Schenk P.M., Kazan K., Wilson I., Anderson J.P., Richmond T., Somerville S.C., Manners J.M. Proc. Natl. Acad. Sci. U.S.A. 97:11655-11660(2000) [PubMed: 11027363] [Abstract] Cited for: INDUCTION. Strain: cv. Columbia.
[10]	"Response of Arabidopsis to iron deficiency stress as revealed by microarray analysis." Thimm O., Essigmann B., Kloska S., Altmann T., Buckhout T.J. Plant Physiol. 127:1030-1043(2001) [PubMed: 11706184] [Abstract] Cited for: INDUCTION. Strain: cv. Columbia.
[11]	"Arabidopsis transcriptome profiling indicates that multiple regulatory pathways are activated during cold acclimation in addition to the CBF cold response pathway." Fowler S., Thomashow M.F. Plant Cell 14:1675-1690(2002) [PubMed: 12172015] [Abstract] Cited for: INDUCTION. Strain: cv. Columbia.
[12]	"Analysis and expression of the class III peroxidase large gene family in Arabidopsis thaliana." Tognolli M., Penel C., Greppin H., Simon P. Gene 288:129-138(2002) [PubMed: 12034502] [Abstract] Cited for: GENE FAMILY ORGANIZATION, NOMENCLATURE. Strain: cv. Columbia.

Hide | Top

Cross-references

Sequence databases
	X98322 mRNA. Translation: CAA66966.1. X98776 mRNA. Translation: CAA67312.1. AB006706 Genomic DNA. Translation: BAB09581.1. BT002958 mRNA. Translation: AAO22769.2. AY087882 mRNA. Translation: AAM65434.1. Different initiation.
RefSeq	NP_197284.1.
UniGene	At.25535
3D structure databases
HSSP	HSSP built from PDB template 1QGJ based on UniProtKB Q39034.
ModBase	Search...
Protein family/group databases
PeroxiBase	223. AtPrx57.
Proteomic databases
PRIDE	Q43729.
Genome annotation databases
GeneID	831650.
GenomeReviews	Gene locus AT5G17820 in contig BA000015_GR.
KEGG	ath:AT5G17820.
Organism-specific databases
GeneFarm	1912. 61.
TAIR	At5g17820.
Gene expression databases
ArrayExpress	Q43729.
GermOnline	AT5G17820. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR002016. Haem_peroxidase_pln/fun/bac. IPR000823. Peroxidase_pln. [Graphical view]
Pfam	PF00141. peroxidase. 1 hit. [Graphical view]
PRINTS	PR00458. PEROXIDASE. PR00461. PLPEROXIDASE.
PROSITE	PS00435. PEROXIDASE_1. 1 hit. PS00436. PEROXIDASE_2. 1 hit. PS50873. PEROXIDASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Hide | Top

Entry information

Entry name

PER57_ARATH

Accession

Primary (citable) accession number: Q43729
Secondary accession number(s): Q84WN8

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 6, 2002
Last sequence update:	November 1, 1996
Last modified:	December 16, 2008
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)

Hide | Top

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Keywords

Gene Ontology (GO)

Sequence annotation (Features)

Molecule processing

Sites

Amino acid modifications

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein family/group databases

Proteomic databases

Genome annotation databases

Organism-specific databases

Gene expression databases

Family and domain databases

Entry information

Relevant documents