Q43497 (MDAR_SOLLC) Reviewed, UniProtKB/Swiss-Prot
Last modified
April 3, 2013.
Version 70.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Monodehydroascorbate reductase Short name=MDAR EC=1.6.5.4 Alternative name(s): Ascorbate free radical reductase Short name=AFR reductase | ||
| Gene names |
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| Organism | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) [Reference proteome] | ||
| Taxonomic identifier | 4081 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum › Lycopersicon![]() |
Protein attributes
| Sequence length | 433 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Function | Catalyzes the conversion of monodehydroascorbate to ascorbate, oxidizing NADH in the process. |
| Catalytic activity | NADH + 2 monodehydroascorbate = NAD+ + 2 ascorbate. Ref.1 |
| Cofactor | FAD By similarity. |
| Subcellular location | |
| Tissue specificity | Expressed in leaves, and to a lesser degree in stems, roots and all stages of fruit. Ref.1 |
| Induction | By wounding. Ref.1 |
| Sequence similarities | Belongs to the FAD-dependent oxidoreductase family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Domain | Redox-active center |
| Ligand | FAD Flavoprotein NAD |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | cell redox homeostasis Inferred from electronic annotation. Source: InterPro |
| Cellular_component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular_function | flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro monodehydroascorbate reductase (NADH) activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 433 | 433 | Monodehydroascorbate reductase | PRO_0000209142 | |||||
Regions | |||||||||
| Nucleotide binding | 7 – 24 | 18 | FAD By similarity UniProtKB P42454 | ||||||
| Nucleotide binding | 165 – 182 | 18 | NAD By similarity UniProtKB P42454 | ||||||
| Nucleotide binding | 191 – 195 | 5 | FAD By similarity UniProtKB P42454 | ||||||
Sequences
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References
| [1] | "Ascorbate free radical reductase mRNA levels are induced by wounding." Grantz A.A., Brummell D.A., Bennett A.B. Plant Physiol. 108:411-418(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CATALYTIC ACTIVITY, TISSUE SPECIFICITY, INDUCTION. Strain: cv. Castlemart. Tissue: Fruit. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | L41345 Genomic DNA. Translation: AAC41654.1. |
| PIR | T06407. |
3D structure databases | |
| ProteinModelPortal | Q43497. |
| ModBase | Search... |
Proteomic databases | |
| PRIDE | Q43497. |
| ProMEX | Q43497. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Family and domain databases | |
| Gene3D | 3.30.390.30. 1 hit. |
| InterPro | IPR016156. FAD/NAD-linked_Rdtase_dimer. IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR004099. Pyr_nucl-diS_OxRdtase_dimer. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. [Graphical view] |
| Pfam | PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view] |
| PRINTS | PR00368. FADPNR. |
| SUPFAM | SSF55424. FAD/NAD-linked_reductase_dimer. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | MDAR_SOLLC | ||||||||
| Accession | Primary (citable) accession number: Q43497 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Plant Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

Clusters with
