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Protein

Lipoxygenase

Gene

vlxB

Organism
Glycine max (Soybean) (Glycine hispida)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.UniRule annotation

Cofactori

Fe cationUniRule annotation

Pathwayi: oxylipin biosynthesis

This protein is involved in the pathway oxylipin biosynthesis, which is part of Lipid metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway oxylipin biosynthesis and in Lipid metabolism.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi513 – 5131Iron; via tele nitrogenCombined sources
Metal bindingi518 – 5181Iron; via tele nitrogenCombined sources
Metal bindingi704 – 7041Iron; via tele nitrogenCombined sources
Metal bindingi708 – 7081IronCombined sources
Metal bindingi853 – 8531IronCombined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

DioxygenaseUniRule annotationSAAS annotation, Oxidoreductase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Oxylipin biosynthesisUniRule annotation

Keywords - Ligandi

IronUniRule annotationCombined sourcesSAAS annotation, Metal-bindingUniRule annotationCombined sourcesSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00382.

Names & Taxonomyi

Protein namesi
Recommended name:
LipoxygenaseUniRule annotation (EC:1.13.11.-UniRule annotation)
Gene namesi
Name:vlxBImported
OrganismiGlycine max (Soybean) (Glycine hispida)Imported
Taxonomic identifieri3847 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja

PTM / Processingi

Proteomic databases

ProMEXiQ43446.

Interactioni

Protein-protein interaction databases

STRINGi3847.GLYMA15G03050.1.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2IUJX-ray2.40A1-853[»]
ProteinModelPortaliQ43446.
SMRiQ43446. Positions 8-853.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ43446.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini29 – 159131PLATInterPro annotationAdd
BLAST
Domaini162 – 853692LipoxygenaseInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the lipoxygenase family.UniRule annotation
Contains PLAT domain.SAAS annotation
Contains lipoxygenase domain.SAAS annotation

Phylogenomic databases

eggNOGiENOG410IH0D. Eukaryota.
ENOG410YN4N. LUCA.
KOiK15718.

Family and domain databases

Gene3Di2.60.60.20. 1 hit.
4.10.372.10. 1 hit.
InterProiIPR000907. LipOase.
IPR013819. LipOase_C.
IPR020834. LipOase_CS.
IPR020833. LipOase_Fe_BS.
IPR001246. LipOase_plant.
IPR027433. Lipoxygenase_domain_3.
IPR001024. PLAT/LH2_dom.
[Graphical view]
PANTHERiPTHR11771. PTHR11771. 2 hits.
PfamiPF00305. Lipoxygenase. 1 hit.
PF01477. PLAT. 1 hit.
[Graphical view]
PRINTSiPR00087. LIPOXYGENASE.
PR00468. PLTLPOXGNASE.
SMARTiSM00308. LH2. 1 hit.
[Graphical view]
SUPFAMiSSF48484. SSF48484. 1 hit.
SSF49723. SSF49723. 1 hit.
PROSITEiPS00711. LIPOXYGENASE_1. 1 hit.
PS00081. LIPOXYGENASE_2. 1 hit.
PS51393. LIPOXYGENASE_3. 1 hit.
PS50095. PLAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q43446-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFPFGHKGQK IKGTMVVMQK NVLDINSITS VDGIVGTGLD FLGSALDTVT
60 70 80 90 100
FLASSISIQL ISATKADGGK GKVGKATNLR GKITLPTIGA KEEAYDAQFD
110 120 130 140 150
WDSDFGIPGA FYIKNYMQNE FYLKSLILED IPNHGTIHFI CNSWVYNSKH
160 170 180 190 200
YKTDRIFFAN NTYLPSETPA PLVKYREEEL KNVRGDGTGE RKEWDRIYDY
210 220 230 240 250
DVYNDLGDPD KGEKYARPVL GGSALPYPRR GRTGRGKTRK DPNSEKPGDF
260 270 280 290 300
VYLPRDEAFG HLKSSDFLAY GIKSVAQDVL PVLTDAFDGN LLSLDFDNFA
310 320 330 340 350
EVRKLYEGGV TLPTNFLSNI TPIPIIKELF RTDGEQFLKY PPPKVMQVDK
360 370 380 390 400
SAWMTDEEFA RETIAGLNPN VIKIIEEFPL SSKLDTQAYG DHTCIITKEH
410 420 430 440 450
LEPNLGGLTV EQAIQNKKLF ILDHHDYLIP YLRKINANTT KTYATRTIFF
460 470 480 490 500
LKNDGTLTPL AIELSKPHPQ GEEYGPVSEV YVPSSEGVEA YIWLLAKAYV
510 520 530 540 550
VVNDACYHQI ISHWLNTHAV VEPFVIATNR HLSVVHPIYK LLFPHYRDTM
560 570 580 590 600
NINSLARKSL VNADGIIEKT FLWGRYSLEM SAVIYKDWVF TDQALPNDLV
610 620 630 640 650
KRGVAVKDPS APHGVRLLIE DYPYASDGLE IWDAIKSWVE EYVSFYYKSD
660 670 680 690 700
EELQKDPELQ AWWKELVEVG HGDLKDKPWW QKMQTREELV EASATLIWIA
710 720 730 740 750
SALHAAVNFG QYPYGGLILN RPTISRRFMP EKGSPEYDAL AKNPEKEFLK
760 770 780 790 800
TITGKKETLI DLTIIEILSR HASDEFYLGQ RDGGDYWTSD AGPLEAFKRF
810 820 830 840 850
GKNLEEIEKK LIEKNNDETL RNRYGPAKMP YTLLYPSSEE GLTFRGIPNS

ISI
Length:853
Mass (Da):96,658
Last modified:November 1, 1996 - v1
Checksum:iFCC4184239490902
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U50075 mRNA. Translation: AAB67732.1.
PIRiT07036.
RefSeqiNP_001238203.1. NM_001251274.1.
UniGeneiGma.31349.

Genome annotation databases

GeneIDi100101853.
KEGGigmx:100101853.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U50075 mRNA. Translation: AAB67732.1.
PIRiT07036.
RefSeqiNP_001238203.1. NM_001251274.1.
UniGeneiGma.31349.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2IUJX-ray2.40A1-853[»]
ProteinModelPortaliQ43446.
SMRiQ43446. Positions 8-853.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3847.GLYMA15G03050.1.

Proteomic databases

ProMEXiQ43446.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100101853.
KEGGigmx:100101853.

Phylogenomic databases

eggNOGiENOG410IH0D. Eukaryota.
ENOG410YN4N. LUCA.
KOiK15718.

Enzyme and pathway databases

UniPathwayiUPA00382.

Miscellaneous databases

EvolutionaryTraceiQ43446.

Family and domain databases

Gene3Di2.60.60.20. 1 hit.
4.10.372.10. 1 hit.
InterProiIPR000907. LipOase.
IPR013819. LipOase_C.
IPR020834. LipOase_CS.
IPR020833. LipOase_Fe_BS.
IPR001246. LipOase_plant.
IPR027433. Lipoxygenase_domain_3.
IPR001024. PLAT/LH2_dom.
[Graphical view]
PANTHERiPTHR11771. PTHR11771. 2 hits.
PfamiPF00305. Lipoxygenase. 1 hit.
PF01477. PLAT. 1 hit.
[Graphical view]
PRINTSiPR00087. LIPOXYGENASE.
PR00468. PLTLPOXGNASE.
SMARTiSM00308. LH2. 1 hit.
[Graphical view]
SUPFAMiSSF48484. SSF48484. 1 hit.
SSF49723. SSF49723. 1 hit.
PROSITEiPS00711. LIPOXYGENASE_1. 1 hit.
PS00081. LIPOXYGENASE_2. 1 hit.
PS51393. LIPOXYGENASE_3. 1 hit.
PS50095. PLAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Sink limitation induces the expression of multiple soybean vegetative lipoxygenase mRNAs while the endogenous jasmonic acid level remains low."
    Bunker T.W., Koetje D.S., Stephenson L.C., Creelman R.A., Mullet J.E., Grimes H.D.
    Plant Cell 7:1319-1331(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LeafImported.
  2. "Nucleotide sequence of vlxB, a vegetative lipoxygenase from soybean (Accession No. U50075) (PGR96-024)."
    Bunker T.W., Grimes H.D.
    Plant Physiol. 111:348-348(1996)
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LeafImported.
  3. "Crystal structures of vegetative soybean lipoxygenase VLX-B and VLX-D, and comparisons with seed isoforms LOX-1 and LOX-3."
    Youn B., Sellhorn G.E., Mirchel R.J., Gaffney B.J., Grimes H.D., Kang C.
    Proteins 65:1008-1020(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) IN COMPLEX WITH IRON.

Entry informationi

Entry nameiQ43446_SOYBN
AccessioniPrimary (citable) accession number: Q43446
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 8, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.