Reviewed,
UniProtKB/Swiss-Prot Q43315 (FPPS2_ARATH)
Last modified
November 25, 2008.
Version 66.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Farnesyl pyrophosphate synthetase 2 Short name=FPP synthetase 2 Short name=FPS 2 Alternative name(s): Farnesyl diphosphate synthetase 2 Including the following 2 domains: 1- Recommended name: Dimethylallyltranstransferase EC=2.5.1.1 2- Recommended name: Geranyltranstransferase EC=2.5.1.10 | ||||||
| Gene names |
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| Organism | Arabidopsis thaliana (Mouse-ear cress) [Complete proteome] | ||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis |
Protein attributes
| Sequence length | 342 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. |
| Catalytic activity | Dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate. Geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate. |
| Pathway | |
| Subcellular location | |
| Sequence similarities | Belongs to the FPP/GGPP synthetase family. |
Ontologies
Keywords | |
|---|---|
| Biological process | Cholesterol biosynthesis Isoprene biosynthesis Lipid synthesis Steroid biosynthesis Sterol biosynthesis |
| Cellular component | Cytoplasm |
| Coding sequence diversity | Alternative splicing |
| Molecular function | Transferase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | cholesterol biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW isoprenoid biosynthetic processInferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | dimethylallyltranstransferase activity Inferred from electronic annotation. Source: EC geranyltranstransferase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Alternative products
| This entry describes 1 isoform produced by alternative splicing. [Select] Notes: A number of isoforms are produced. According to EST sequences. | ||||||
| Isoform 1 (identifier: Q43315-1) This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 342 | 342 | Farnesyl pyrophosphate synthetase 2 | PRO_0000123953 | |||
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| L46350 Genomic DNA. Translation: AAB07247.1. L46349 mRNA. Translation: AAB07248.1. Z97343 Genomic DNA. Translation: CAB10500.1. AL161545 Genomic DNA. Translation: CAB80990.1. AY072207 mRNA. Translation: AAL60028.1. AY117354 mRNA. Translation: AAM51429.1. | |
| PIR | S71182. |
| RefSeq | NP_193452.1. |
| UniGene | At.21195 |
3D structure databases | |
| HSSP | HSSP built from PDB template 1UBX based on UniProtKB P08836. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 827430. |
| GenomeReviews | Gene locus AT4G17190 in contig CT486007_GR. |
| KEGG | ath:AT4G17190. |
| NMPDR | fig|3702.1.peg.19505. |
Organism-specific databases | |
| TAIR | At4g17190. |
Enzyme and pathway databases | |
| BioCyc | MetaCyc:AT4G17190-MON. |
Gene expression databases | |
| ArrayExpress | Q43315. |
Family and domain databases | |
| InterPro | IPR000092. Polyprenyl_synt. IPR008949. Terpenoid_synth. [Graphical view] |
| Gene3D | G3DSA:1.10.600.10. Terpenoid_synth. 1 hit. |
| Pfam | PF00348. polyprenyl_synt. 1 hit. [Graphical view] |
| PROSITE | PS00723. POLYPRENYL_SYNTHET_1. 1 hit. PS00444. POLYPRENYL_SYNTHET_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | FPPS2_ARATH | ||||||||
| Accession | Primary (citable) accession number: Q43315 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


