ID   DHE1_ARATH              Reviewed;         411 AA.
AC   Q43314;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   16-JUN-2009, entry version 66.
DE   RecName: Full=Glutamate dehydrogenase 1;
DE            Short=GDH 1;
DE            EC=1.4.1.3;
GN   Name=GDH1; OrderedLocusNames=At5g18170; ORFNames=MRG7.13;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Thakkar S., Weisemann J.M., Turano F.J.;
RT   "Arabidopsis glutamate dehydrogenase 1.";
RL   Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Columbia;
RA   Melo-Oliveira R., Oliveira I., Coruzzi G.;
RT   "Arabidopsis mutant analysis and gene regulation define a nonredundant
RT   role for glutamate dehydrogenase in nitrogen assimilation.";
RL   Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   MEDLINE=98403884; PubMed=9734815; DOI=10.1093/dnares/5.3.203;
RA   Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. VI.
RT   Sequence features of the regions of 1,367,185 bp covered by 19
RT   physically assigned P1 and TAC clones.";
RL   DNA Res. 5:203-216(1998).
CC   -!- CATALYTIC ACTIVITY: L-glutamate + H(2)O + NAD(P)(+) = 2-
CC       oxoglutarate + NH(3) + NAD(P)H.
CC   -!- SIMILARITY: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
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DR   EMBL; U37771; AAA82615.1; -; mRNA.
DR   EMBL; U53527; AAB08057.1; -; mRNA.
DR   EMBL; AB012246; BAB09475.1; -; Genomic_DNA.
DR   IPI; IPI00531762; -.
DR   PIR; S71217; S71217.
DR   RefSeq; NP_197318.1; -.
DR   UniGene; At.23609; -.
DR   HSSP; P96110; 1B26.
DR   PRIDE; Q43314; -.
DR   ProMEX; Q43314; -.
DR   GeneID; 831935; -.
DR   GenomeReviews; BA000015_GR; AT5G18170.
DR   KEGG; ath:AT5G18170; -.
DR   NMPDR; fig|3702.1.peg.23989; -.
DR   GeneFarm; 2257; 178.
DR   TAIR; At5g18170; -.
DR   OMA; Q43314; GIRIDPR.
DR   BRENDA; 1.4.1.3; 302.
DR   ArrayExpress; Q43314; -.
DR   GermOnline; AT5G18170; Arabidopsis thaliana.
DR   GO; GO:0005739; C:mitochondrion; IDA:TAIR.
DR   GO; GO:0005524; F:ATP binding; IDA:TAIR.
DR   GO; GO:0004353; F:glutamate dehydrogenase [NAD(P)+] activity; IDA:TAIR.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   GO; GO:0009646; P:response to absence of light; IEP:TAIR.
DR   GO; GO:0046686; P:response to cadmium ion; IEP:TAIR.
DR   GO; GO:0009651; P:response to salt stress; IEP:TAIR.
DR   InterPro; IPR006095; Glu/Leu/Phe/Val_DH.
DR   InterPro; IPR006096; Glu/Leu/Phe/Val_DH_C.
DR   InterPro; IPR006097; Glu/Leu/Phe/Val_DH_dimer.
DR   InterPro; IPR014362; Glu_DH.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR11606:SF2; GLFV_DH; 1.
DR   Pfam; PF00208; ELFV_dehydrog; 1.
DR   Pfam; PF02812; ELFV_dehydrog_N; 1.
DR   PIRSF; PIRSF000185; Glu_DH; 1.
DR   PRINTS; PR00082; GLFDHDRGNASE.
DR   PROSITE; PS00074; GLFV_DEHYDROGENASE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome; NAD; Oxidoreductase.
FT   CHAIN         1    411       Glutamate dehydrogenase 1.
FT                                /FTId=PRO_0000182745.
FT   ACT_SITE    102    102       By similarity.
SQ   SEQUENCE   411 AA;  44524 MW;  4F14E31CEC52935E CRC64;
     MNALAATNRN FKLAARLLGL DSKLEKSLLI PFREIKVECT IPKDDGTLAS FVGFRVQHDN
     ARGPMKGGIR YHPEVDPDEV NALAQLMTWK TAVAKIPYGG AKGGIGCDPS KLSISELERL
     TRVFTQKIHD LIGIHTDVPA PDMGTGPQTM AWILDEYSKF HGYSPAVVTG KPIDLGGSLG
     RDAATGRGVM FGTEALLNEH GKTISGQRFV IQGFGNVGSW AAKLISEKGG KIVAVSDITG
     AIKNKDGIDI PALLKHTKEH RGVKGFDGAD PIDPNSILVE DCDILVPAAL GGVINRENAN
     EIKAKFIIEA ANHPTDPDAD EILSKKGVVI LPDIYANSGG VTVSYFEWVQ NIQGFMWEEE
     KVNDELKTYM TRSFKDLKEM CKTHSCDLRM GAFTLGVNRV AQATILRGWG A
//