Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q43314 (DHE1_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 103. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamate dehydrogenase 1

Short name=GDH 1
EC=1.4.1.3
Gene names
Name:GDH1
Ordered Locus Names:At5g18170
ORF Names:MRG7.13
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length411 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H.

Sequence similarities

Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 411411Glutamate dehydrogenase 1
PRO_0000182745

Sites

Active site1021 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q43314 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 4F14E31CEC52935E

FASTA41144,524
        10         20         30         40         50         60 
MNALAATNRN FKLAARLLGL DSKLEKSLLI PFREIKVECT IPKDDGTLAS FVGFRVQHDN 

        70         80         90        100        110        120 
ARGPMKGGIR YHPEVDPDEV NALAQLMTWK TAVAKIPYGG AKGGIGCDPS KLSISELERL 

       130        140        150        160        170        180 
TRVFTQKIHD LIGIHTDVPA PDMGTGPQTM AWILDEYSKF HGYSPAVVTG KPIDLGGSLG 

       190        200        210        220        230        240 
RDAATGRGVM FGTEALLNEH GKTISGQRFV IQGFGNVGSW AAKLISEKGG KIVAVSDITG 

       250        260        270        280        290        300 
AIKNKDGIDI PALLKHTKEH RGVKGFDGAD PIDPNSILVE DCDILVPAAL GGVINRENAN 

       310        320        330        340        350        360 
EIKAKFIIEA ANHPTDPDAD EILSKKGVVI LPDIYANSGG VTVSYFEWVQ NIQGFMWEEE 

       370        380        390        400        410 
KVNDELKTYM TRSFKDLKEM CKTHSCDLRM GAFTLGVNRV AQATILRGWG A 

« Hide

References

« Hide 'large scale' references
[1]"Arabidopsis glutamate dehydrogenase 1."
Thakkar S., Weisemann J.M., Turano F.J.
Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Arabidopsis mutant analysis and gene regulation define a nonredundant role for glutamate dehydrogenase in nitrogen assimilation."
Melo-Oliveira R., Oliveira I., Coruzzi G.
Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Columbia.
[3]"Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence features of the regions of 1,367,185 bp covered by 19 physically assigned P1 and TAC clones."
Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N., Tabata S.
DNA Res. 5:203-216(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[4]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U37771 mRNA. Translation: AAA82615.1.
U53527 mRNA. Translation: AAB08057.1.
AB012246 Genomic DNA. Translation: BAB09475.1.
CP002688 Genomic DNA. Translation: AED92515.1.
PIRS71217.
RefSeqNP_197318.1. NM_121822.3.
UniGeneAt.23609.

3D structure databases

ProteinModelPortalQ43314.
SMRQ43314. Positions 11-407.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ43314. 1 interaction.

Proteomic databases

PaxDbQ43314.
PRIDEQ43314.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G18170.1; AT5G18170.1; AT5G18170.
GeneID831935.
KEGGath:AT5G18170.

Organism-specific databases

GeneFarm2257. 178.
TAIRAT5G18170.

Phylogenomic databases

eggNOGCOG0334.
HOGENOMHOG000243801.
InParanoidQ43314.
KOK00261.
OMAIIIGPSK.
PhylomeDBQ43314.
ProtClustDBPLN02477.

Enzyme and pathway databases

BioCycARA:AT5G18170-MONOMER.

Gene expression databases

GenevestigatorQ43314.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR006095. Glu/Leu/Phe/Val_DH.
IPR006096. Glu/Leu/Phe/Val_DH_C.
IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
IPR014362. Glu_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
[Graphical view]
PIRSFPIRSF000185. Glu_DH. 1 hit.
PRINTSPR00082. GLFDHDRGNASE.
SMARTSM00839. ELFV_dehydrog. 1 hit.
[Graphical view]
PROSITEPS00074. GLFV_DEHYDROGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDHE1_ARATH
AccessionPrimary (citable) accession number: Q43314
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names