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Reviewed, UniProtKB/Swiss-Prot Q43314 (DHE1_ARATH)

Last modified November 25, 2008. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Glutamate dehydrogenase 1
      Short name=GDH 1
    EC=1.4.1.3
Gene names
Name: GDH1
Ordered Locus Names: At5g18170
ORF Names: MRG7.13
OrganismArabidopsis thaliana (Mouse-ear cress) [Complete proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

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Protein attributes

Sequence length411 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Catalytic activity

L-glutamate + H(2)O + NAD(P)(+) = 2-oxoglutarate + NH(3) + NAD(P)H.

Sequence similarities

Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

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Ontologies

Keywords

   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome

Gene Ontology (GO)

   Biological processamino acid metabolic process

Inferred from electronic annotation. Source: InterPro

oxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionbinding

Inferred from electronic annotation. Source: InterPro

glutamate dehydrogenase [NAD(P)+] activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 411411Glutamate dehydrogenase 1
PRO_0000182745

Sites

Active site1021 By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q43314-1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 4F14E31CEC52935E

FASTA41144,524
        10         20         30         40         50         60 
MNALAATNRN FKLAARLLGL DSKLEKSLLI PFREIKVECT IPKDDGTLAS FVGFRVQHDN 

        70         80         90        100        110        120 
ARGPMKGGIR YHPEVDPDEV NALAQLMTWK TAVAKIPYGG AKGGIGCDPS KLSISELERL 

       130        140        150        160        170        180 
TRVFTQKIHD LIGIHTDVPA PDMGTGPQTM AWILDEYSKF HGYSPAVVTG KPIDLGGSLG 

       190        200        210        220        230        240 
RDAATGRGVM FGTEALLNEH GKTISGQRFV IQGFGNVGSW AAKLISEKGG KIVAVSDITG 

       250        260        270        280        290        300 
AIKNKDGIDI PALLKHTKEH RGVKGFDGAD PIDPNSILVE DCDILVPAAL GGVINRENAN 

       310        320        330        340        350        360 
EIKAKFIIEA ANHPTDPDAD EILSKKGVVI LPDIYANSGG VTVSYFEWVQ NIQGFMWEEE 

       370        380        390        400        410 
KVNDELKTYM TRSFKDLKEM CKTHSCDLRM GAFTLGVNRV AQATILRGWG A

« Hide

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References

« Hide 'large scale' references
[1]"Arabidopsis glutamate dehydrogenase 1."
Thakkar S., Weisemann J.M., Turano F.J.
Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Arabidopsis mutant analysis and gene regulation define a nonredundant role for glutamate dehydrogenase in nitrogen assimilation."
Melo-Oliveira R., Oliveira I., Coruzzi G.
Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Columbia.
[3]"Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence features of the regions of 1,367,185 bp covered by 19 physically assigned P1 and TAC clones."
Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N., Tabata S.
DNA Res. 5:203-216(1998) [PubMed: 9734815] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.

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Cross-references

Sequence databases

U37771 mRNA. Translation: AAA82615.1.
U53527 mRNA. Translation: AAB08057.1.
AB012246 Genomic DNA. Translation: BAB09475.1.
PIRS71217.
RefSeqNP_197318.1.
UniGeneAt.23609

3D structure databases

HSSPHSSP built from PDB template 1B26 based on UniProtKB P96110.
ModBaseSearch...

Proteomic databases

ProMEXQ43314.

Genome annotation databases

GeneID831935.
GenomeReviewsGene locus AT5G18170 in contig BA000015_GR.
KEGGath:AT5G18170.
NMPDRfig|3702.1.peg.23989.

Organism-specific databases

GeneFarm2257. 178.
TAIRAt5g18170.

Gene expression databases

ArrayExpressQ43314.
GermOnlineAT5G18170. Arabidopsis thaliana.

Family and domain databases

InterProIPR006095. Glu/Leu/Phe/Val_DHase.
IPR006096. Glu/Leu/Phe/Val_DHase_C.
IPR006097. Glu/Leu/Phe/Val_DHase_dimer.
IPR014362. Glu_DHase.
IPR016040. NAD(P)-bd.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHERPTHR11606:SF2. GLFV_DH. 1 hit.
PfamPF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
[Graphical view]
PIRSFPIRSF000185. Glu_DH. 1 hit.
PRINTSPR00082. GLFDHDRGNASE.
PROSITEPS00074. GLFV_DEHYDROGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameDHE1_ARATH
AccessionPrimary (citable) accession number: Q43314
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: November 25, 2008
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

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Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents