Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q43314

- DHE1_ARATH

UniProt

Q43314 - DHE1_ARATH

Protein

Glutamate dehydrogenase 1

Gene

GDH1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 105 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H.PROSITE-ProRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei102 – 1021PROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: TAIR
    2. cobalt ion binding Source: TAIR
    3. copper ion binding Source: TAIR
    4. glutamate dehydrogenase [NAD(P)+] activity Source: TAIR
    5. zinc ion binding Source: TAIR

    GO - Biological processi

    1. cellular amino acid metabolic process Source: InterPro
    2. nitrogen compound metabolic process Source: TAIR
    3. response to absence of light Source: TAIR
    4. response to cadmium ion Source: TAIR
    5. response to salt stress Source: TAIR

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciARA:AT5G18170-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate dehydrogenase 1 (EC:1.4.1.3)
    Short name:
    GDH 1
    Gene namesi
    Name:GDH1
    Ordered Locus Names:At5g18170
    ORF Names:MRG7.13
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 5

    Organism-specific databases

    TAIRiAT5G18170.

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrion Source: TAIR

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 411411Glutamate dehydrogenase 1PRO_0000182745Add
    BLAST

    Proteomic databases

    PaxDbiQ43314.
    PRIDEiQ43314.

    Expressioni

    Gene expression databases

    GenevestigatoriQ43314.

    Interactioni

    Protein-protein interaction databases

    IntActiQ43314. 1 interaction.

    Structurei

    3D structure databases

    ProteinModelPortaliQ43314.
    SMRiQ43314. Positions 11-407.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0334.
    HOGENOMiHOG000243801.
    InParanoidiQ43314.
    KOiK00261.
    OMAiNANDIMA.
    PhylomeDBiQ43314.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR006095. Glu/Leu/Phe/Val_DH.
    IPR006096. Glu/Leu/Phe/Val_DH_C.
    IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
    IPR014362. Glu_DH.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF00208. ELFV_dehydrog. 1 hit.
    PF02812. ELFV_dehydrog_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000185. Glu_DH. 1 hit.
    PRINTSiPR00082. GLFDHDRGNASE.
    SMARTiSM00839. ELFV_dehydrog. 1 hit.
    [Graphical view]
    PROSITEiPS00074. GLFV_DEHYDROGENASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q43314-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNALAATNRN FKLAARLLGL DSKLEKSLLI PFREIKVECT IPKDDGTLAS    50
    FVGFRVQHDN ARGPMKGGIR YHPEVDPDEV NALAQLMTWK TAVAKIPYGG 100
    AKGGIGCDPS KLSISELERL TRVFTQKIHD LIGIHTDVPA PDMGTGPQTM 150
    AWILDEYSKF HGYSPAVVTG KPIDLGGSLG RDAATGRGVM FGTEALLNEH 200
    GKTISGQRFV IQGFGNVGSW AAKLISEKGG KIVAVSDITG AIKNKDGIDI 250
    PALLKHTKEH RGVKGFDGAD PIDPNSILVE DCDILVPAAL GGVINRENAN 300
    EIKAKFIIEA ANHPTDPDAD EILSKKGVVI LPDIYANSGG VTVSYFEWVQ 350
    NIQGFMWEEE KVNDELKTYM TRSFKDLKEM CKTHSCDLRM GAFTLGVNRV 400
    AQATILRGWG A 411
    Length:411
    Mass (Da):44,524
    Last modified:November 1, 1996 - v1
    Checksum:i4F14E31CEC52935E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U37771 mRNA. Translation: AAA82615.1.
    U53527 mRNA. Translation: AAB08057.1.
    AB012246 Genomic DNA. Translation: BAB09475.1.
    CP002688 Genomic DNA. Translation: AED92515.1.
    PIRiS71217.
    RefSeqiNP_197318.1. NM_121822.3.
    UniGeneiAt.23609.

    Genome annotation databases

    EnsemblPlantsiAT5G18170.1; AT5G18170.1; AT5G18170.
    GeneIDi831935.
    KEGGiath:AT5G18170.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U37771 mRNA. Translation: AAA82615.1 .
    U53527 mRNA. Translation: AAB08057.1 .
    AB012246 Genomic DNA. Translation: BAB09475.1 .
    CP002688 Genomic DNA. Translation: AED92515.1 .
    PIRi S71217.
    RefSeqi NP_197318.1. NM_121822.3.
    UniGenei At.23609.

    3D structure databases

    ProteinModelPortali Q43314.
    SMRi Q43314. Positions 11-407.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q43314. 1 interaction.

    Proteomic databases

    PaxDbi Q43314.
    PRIDEi Q43314.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT5G18170.1 ; AT5G18170.1 ; AT5G18170 .
    GeneIDi 831935.
    KEGGi ath:AT5G18170.

    Organism-specific databases

    GeneFarmi 2257. 178.
    TAIRi AT5G18170.

    Phylogenomic databases

    eggNOGi COG0334.
    HOGENOMi HOG000243801.
    InParanoidi Q43314.
    KOi K00261.
    OMAi NANDIMA.
    PhylomeDBi Q43314.

    Enzyme and pathway databases

    BioCyci ARA:AT5G18170-MONOMER.

    Gene expression databases

    Genevestigatori Q43314.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR006095. Glu/Leu/Phe/Val_DH.
    IPR006096. Glu/Leu/Phe/Val_DH_C.
    IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
    IPR014362. Glu_DH.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF00208. ELFV_dehydrog. 1 hit.
    PF02812. ELFV_dehydrog_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000185. Glu_DH. 1 hit.
    PRINTSi PR00082. GLFDHDRGNASE.
    SMARTi SM00839. ELFV_dehydrog. 1 hit.
    [Graphical view ]
    PROSITEi PS00074. GLFV_DEHYDROGENASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Arabidopsis glutamate dehydrogenase 1."
      Thakkar S., Weisemann J.M., Turano F.J.
      Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    2. "Arabidopsis mutant analysis and gene regulation define a nonredundant role for glutamate dehydrogenase in nitrogen assimilation."
      Melo-Oliveira R., Oliveira I., Coruzzi G.
      Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Columbia.
    3. "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence features of the regions of 1,367,185 bp covered by 19 physically assigned P1 and TAC clones."
      Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N., Tabata S.
      DNA Res. 5:203-216(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    4. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.

    Entry informationi

    Entry nameiDHE1_ARATH
    AccessioniPrimary (citable) accession number: Q43314
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 105 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3