Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chaperonin CPN60-2, mitochondrial

Gene

CPN60II

Organism
Zea mays (Maize)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperonin CPN60-2, mitochondrial
Alternative name(s):
HSP60-2
Gene namesi
Name:CPN60II
Synonyms:CPNB
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
Proteomesi
  • UP000007305 Componenti: Chromosome 1

Organism-specific databases

MaizeGDBi65675.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 34MitochondrionBy similarityAdd BLAST34
ChainiPRO_000000501535 – 576Chaperonin CPN60-2, mitochondrialAdd BLAST542

Proteomic databases

PaxDbiQ43298.
PRIDEiQ43298.

Expressioni

Inductioni

By heat shock.

Gene expression databases

ExpressionAtlasiQ43298. baseline and differential.
GenevisibleiQ43298. ZM.

Interactioni

Protein-protein interaction databases

STRINGi4577.GRMZM2G416120_P01.

Structurei

3D structure databases

ProteinModelPortaliQ43298.
SMRiQ43298.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG0356. Eukaryota.
COG0459. LUCA.
KOiK04077.
OMAiTDTDKME.
OrthoDBiEOG093606CJ.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR037290. Cpn60/TCP-1_sf.
IPR027409. GroEL-like_apical_dom_sf.
IPR027413. GROEL-like_equatorial_sf.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q43298-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYRAAASLAS KARQAGSSSA ARQVGSRLAW SRNYAAKDIK FGVEARALML
60 70 80 90 100
RGVEELADAV KVTMGPKGRN VVIEQSFGAP KVTKDGVTVA KSIEFKDRVK
110 120 130 140 150
NVGASLVKQV ANATNDTAGD GTTCATVLTK AIFTEGCKSV AAGMNAMDLR
160 170 180 190 200
RGISMAVDAV VTNLKGMARM ISTSEEIAQV GTISANGERE IGELIAKAME
210 220 230 240 250
KVGKEGVITI ADGNTLYNEL EVVEGMKLDR GYISPYFITN SKAQKCELED
260 270 280 290 300
PLILIHDKKV TNMHAVVKVL EMALKKQRPL LIVAEDVESE ALGTLIINKL
310 320 330 340 350
RAGIKVCAVK APGFGENRKA NLQDLAILTG GEVITEELGM NLENVEPHML
360 370 380 390 400
GSCKKVTVSK DDTVILDGAG DKKSIEERAD QIRSAVENST SDYDKEKLQE
410 420 430 440 450
RLAKLSGGVA VLKIGGASEA EVGEKKDRVT DALNATKAAV EEGIVPGGGV
460 470 480 490 500
ALLYASKELD KLQTANFDQK IGVQIIQNAL KTPVHTIASN AGVEGAVVVG
510 520 530 540 550
KLLEQGNTDL GYDAAKDEYV DMVKAGIIDP LKVIRTALVD AASVSSLMTT
560 570
TESIIVEIPK EEAPAPAMGG MGGMDY
Length:576
Mass (Da):60,935
Last modified:November 1, 1997 - v1
Checksum:i1039FB77D7895321
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti117T → N in CAA78101 (Ref. 2) Curated1
Sequence conflicti248L → P in CAA78101 (Ref. 2) Curated1
Sequence conflicti258K → R in CAA78101 (Ref. 2) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L21008 Genomic DNA. Translation: AAA33451.1.
L21006 mRNA. Translation: AAA33452.1.
Z12115 mRNA. Translation: CAA78101.1.
PIRiS26583.
RefSeqiNP_001105690.1. NM_001112220.1.
UniGeneiZm.89.

Genome annotation databases

EnsemblPlantsiZm00001d032789_T001; Zm00001d032789_P001; Zm00001d032789.
GeneIDi542707.
GrameneiZm00001d032789_T001; Zm00001d032789_P001; Zm00001d032789.
KEGGizma:542707.

Similar proteinsi

Entry informationi

Entry nameiCH62_MAIZE
AccessioniPrimary (citable) accession number: Q43298
Secondary accession number(s): Q43253
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 22, 2017
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families