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Q43260 (DHE3_MAIZE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamate dehydrogenase

Short name=GDH
EC=1.4.1.3
Gene names
Name:GDH1
OrganismZea mays (Maize)
Taxonomic identifier4577 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeZea

Protein attributes

Sequence length411 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H.

Sequence similarities

Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 411411Glutamate dehydrogenase
PRO_0000182749

Sites

Active site1021 By similarity

Natural variations

Natural variant181L → V in strain: cv. P-10 Inbred.
Natural variant3701I → M in strain: cv. P-10 Inbred.
Natural variant3761N → D in strain: cv. P-10 Inbred.

Experimental info

Mutagenesis1881G → R in GDH1.
Mutagenesis2461D → G in GDH1.
Mutagenesis252 – 2532QL → EV in GDH1.
Mutagenesis3671R → Q in GDH1.

Sequences

Sequence LengthMass (Da)Tools
Q43260 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 648C67A9338922CF

FASTA41144,022
        10         20         30         40         50         60 
MNALAATSRN FKQAAKLLGL DSKLEKSLLI PFREIKVECT IPKDDGTLAS YVGFRVQHDN 

        70         80         90        100        110        120 
ARGPMKGGIR YHHEVDPDEV NALAQLMTWK TAVANIPYGG AKGGIGCSPG DLSISELERL 

       130        140        150        160        170        180 
TRVFTQKIHD LIGIHTDVPA PDMGTNSQTM AWILDEYSKF HGYSPAVVTG KPVDLGGSLG 

       190        200        210        220        230        240 
RDAATGRGVL FATEALLAEH GKGIAGQRFV IQGFGNVGSW AAQLISEAGG KVIAISDVTG 

       250        260        270        280        290        300 
AVKNVDGLDI AQLVKHSAEN KGIKGFKGGD AIAPDSLLTE ECDVLIPAAL GGVINKDNAN 

       310        320        330        340        350        360 
DIKAKYIIEA ANHPTDPEAD EILSKKGVLI LPDILANSGG VTVSYFEWVQ NIQGFMWDEE 

       370        380        390        400        410 
KVNAELRTYI TRAFGNVKQM CRSHSCDLRM GAFTLGVNRV ARATVLRGWE A 

« Hide

References

[1]"Isolation and characterization of a cDNA that encodes maize glutamate dehydrogenase."
Sakakibara H., Fujii K., Sugiyama T.
Plant Cell Physiol. 36:789-797(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Golden cross Bantam T51.
Tissue: Root.
[2]"Characterization of a GDH1-mutant in maize."
Ju G.C.
Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA], MUTANT GDH1.
Strain: cv. P-10 Inbred.
Tissue: Shoot.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D49475 mRNA. Translation: BAA08445.1.
U93560 mRNA. Translation: AAB51595.1.
U93561 mRNA. Translation: AAB51596.1.
PIRT03294.
T04342.
RefSeqNP_001105301.1. NM_001111831.1.
UniGeneZm.160907.

3D structure databases

ProteinModelPortalQ43260.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ43260.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID542220.
KEGGzma:542220.

Organism-specific databases

GrameneQ43260.
MaizeGDB12238.

Phylogenomic databases

HOGENOMHOG000243801.
KOK00261.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR006095. Glu/Leu/Phe/Val_DH.
IPR006096. Glu/Leu/Phe/Val_DH_C.
IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
IPR014362. Glu_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
[Graphical view]
PIRSFPIRSF000185. Glu_DH. 1 hit.
PRINTSPR00082. GLFDHDRGNASE.
SMARTSM00839. ELFV_dehydrog. 1 hit.
[Graphical view]
PROSITEPS00074. GLFV_DEHYDROGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDHE3_MAIZE
AccessionPrimary (citable) accession number: Q43260
Secondary accession number(s): O04871, O04872
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: July 9, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families