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Protein

Glutamate dehydrogenase

Gene

GDH1

Organism
Zea mays (Maize)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei102PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate dehydrogenase (EC:1.4.1.3)
Short name:
GDH
Gene namesi
Name:GDH1
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
Proteomesi
  • UP000007305 Componenti: Unplaced

Organism-specific databases

MaizeGDBi12238.

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi188G → R in GDH1. 1
Mutagenesisi246D → G in GDH1. 1
Mutagenesisi252 – 253QL → EV in GDH1. 2
Mutagenesisi367R → Q in GDH1. 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001827491 – 411Glutamate dehydrogenaseAdd BLAST411

Proteomic databases

PaxDbiQ43260.
PRIDEiQ43260.

Expressioni

Gene expression databases

ExpressionAtlasiQ43260. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi4577.GRMZM2G178415_P01.

Structurei

3D structure databases

ProteinModelPortaliQ43260.
SMRiQ43260.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG2250. Eukaryota.
COG0334. LUCA.
HOGENOMiHOG000243801.
KOiK00261.

Family and domain databases

CDDicd01076. NAD_bind_1_Glu_DH. 1 hit.
InterProiView protein in InterPro
IPR006095. Glu/Leu/Phe/Val_DH.
IPR033524. Glu/Leu/Phe/Val_DH_AS.
IPR006096. Glu/Leu/Phe/Val_DH_C.
IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
IPR014362. Glu_DH.
IPR036291. NAD(P)-bd_dom_sf.
IPR033922. NAD_bind_Glu_DH.
PfamiView protein in Pfam
PF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
PIRSFiPIRSF000185. Glu_DH. 1 hit.
PRINTSiPR00082. GLFDHDRGNASE.
SMARTiView protein in SMART
SM00839. ELFV_dehydrog. 1 hit.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiView protein in PROSITE
PS00074. GLFV_DEHYDROGENASE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q43260-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNALAATSRN FKQAAKLLGL DSKLEKSLLI PFREIKVECT IPKDDGTLAS
60 70 80 90 100
YVGFRVQHDN ARGPMKGGIR YHHEVDPDEV NALAQLMTWK TAVANIPYGG
110 120 130 140 150
AKGGIGCSPG DLSISELERL TRVFTQKIHD LIGIHTDVPA PDMGTNSQTM
160 170 180 190 200
AWILDEYSKF HGYSPAVVTG KPVDLGGSLG RDAATGRGVL FATEALLAEH
210 220 230 240 250
GKGIAGQRFV IQGFGNVGSW AAQLISEAGG KVIAISDVTG AVKNVDGLDI
260 270 280 290 300
AQLVKHSAEN KGIKGFKGGD AIAPDSLLTE ECDVLIPAAL GGVINKDNAN
310 320 330 340 350
DIKAKYIIEA ANHPTDPEAD EILSKKGVLI LPDILANSGG VTVSYFEWVQ
360 370 380 390 400
NIQGFMWDEE KVNAELRTYI TRAFGNVKQM CRSHSCDLRM GAFTLGVNRV
410
ARATVLRGWE A
Length:411
Mass (Da):44,022
Last modified:November 1, 1996 - v1
Checksum:i648C67A9338922CF
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti18L → V in strain: cv. P-10 Inbred. 1
Natural varianti370I → M in strain: cv. P-10 Inbred. 1
Natural varianti376N → D in strain: cv. P-10 Inbred. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D49475 mRNA. Translation: BAA08445.1.
U93560 mRNA. Translation: AAB51595.1.
U93561 mRNA. Translation: AAB51596.1.
PIRiT03294.
T04342.
RefSeqiNP_001105301.1. NM_001111831.1.
UniGeneiZm.160907.
Zm.44.

Genome annotation databases

GeneIDi542220.
KEGGizma:542220.

Similar proteinsi

Entry informationi

Entry nameiDHE3_MAIZE
AccessioniPrimary (citable) accession number: Q43260
Secondary accession number(s): O04871, O04872
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: January 31, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families