Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q43207

- FKB70_WHEAT

UniProt

Q43207 - FKB70_WHEAT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

70 kDa peptidyl-prolyl isomerase

Gene

FKBP70

Organism
Triticum aestivum (Wheat)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

PPIases accelerate the folding of proteins during protein synthesis.

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).

GO - Molecular functioni

  1. peptidyl-prolyl cis-trans isomerase activity Source: UniProtKB-KW

GO - Biological processi

  1. protein folding Source: UniProtKB-KW
  2. response to stress Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Isomerase, Rotamase

Keywords - Biological processi

Stress response

Keywords - Ligandi

Calmodulin-binding

Names & Taxonomyi

Protein namesi
Recommended name:
70 kDa peptidyl-prolyl isomerase (EC:5.2.1.8)
Alternative name(s):
Peptidyl-prolyl cis-trans isomerase
Short name:
PPIase
Rotamase
Gene namesi
Name:FKBP70
OrganismiTriticum aestivum (Wheat)
Taxonomic identifieri4565 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaeTriticeaeTriticum
ProteomesiUP000019116: Unplaced

Organism-specific databases

GrameneiQ43207.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 55955970 kDa peptidyl-prolyl isomerasePRO_0000075335Add
BLAST

Expressioni

Inductioni

By heat shock.

Interactioni

Subunit structurei

This PPIase probably binds calmodulin.

Structurei

Secondary structure

1
559
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi34 – 363Combined sources
Beta strandi62 – 665Combined sources
Turni91 – 944Combined sources
Helixi100 – 1067Combined sources
Beta strandi112 – 1165Combined sources
Beta strandi139 – 14810Combined sources
Beta strandi150 – 1523Combined sources
Beta strandi155 – 16511Combined sources
Beta strandi168 – 1703Combined sources
Beta strandi178 – 18710Combined sources
Beta strandi192 – 20211Combined sources
Helixi203 – 2053Combined sources
Beta strandi207 – 2093Combined sources
Helixi210 – 2167Combined sources
Beta strandi224 – 2296Combined sources
Helixi231 – 2333Combined sources
Turni234 – 2385Combined sources
Beta strandi255 – 26511Combined sources
Beta strandi267 – 2715Combined sources
Beta strandi276 – 2827Combined sources
Beta strandi285 – 2873Combined sources
Beta strandi295 – 30713Combined sources
Beta strandi309 – 3146Combined sources
Beta strandi322 – 3243Combined sources
Turni325 – 3284Combined sources
Helixi332 – 3387Combined sources
Beta strandi346 – 3516Combined sources
Helixi353 – 3553Combined sources
Turni356 – 3594Combined sources
Beta strandi362 – 3687Combined sources
Beta strandi374 – 38411Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3JXVX-ray2.08A31-386[»]
3JYMX-ray2.28A/B15-391[»]
ProteinModelPortaliQ43207.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ43207.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini60 – 14889PPIase FKBP-type 1PROSITE-ProRule annotationAdd
BLAST
Domaini176 – 26590PPIase FKBP-type 2PROSITE-ProRule annotationAdd
BLAST
Domaini293 – 38492PPIase FKBP-type 3PROSITE-ProRule annotationAdd
BLAST
Repeati401 – 43434TPR 1Add
BLAST
Repeati450 – 48334TPR 2Add
BLAST
Repeati484 – 51734TPR 3Add
BLAST

Sequence similaritiesi

Contains 3 PPIase FKBP-type domains.PROSITE-ProRule annotation
Contains 3 TPR repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, TPR repeat

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR023566. PPIase_FKBP.
IPR001179. PPIase_FKBP_dom.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR001440. TPR_1.
IPR013105. TPR_2.
IPR019734. TPR_repeat.
[Graphical view]
PANTHERiPTHR10516. PTHR10516. 1 hit.
PfamiPF00254. FKBP_C. 3 hits.
PF00515. TPR_1. 2 hits.
PF07719. TPR_2. 1 hit.
[Graphical view]
SMARTiSM00028. TPR. 3 hits.
[Graphical view]
PROSITEiPS50059. FKBP_PPIASE. 3 hits.
PS50005. TPR. 3 hits.
PS50293. TPR_REGION. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q43207-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDDDFDIPAG DDMMMGDGMG DFGGAEGPGM KVGEENEIGK QGLKKKLLKE
60 70 80 90 100
GEGWDTPEVG DEVEVHYTGT LLDGKKFDSS RDRDDTFKFK LGQGQVIKGW
110 120 130 140 150
DQGIKTMKKG ENALFTIPPE LAYGESGSPP TIPANATLQF DVELLSWTSV
160 170 180 190 200
RDIAKDGGIF KKILKEGDKW ENPKDPDEVF VKYEARLEDG TVVSKSEGVE
210 220 230 240 250
FTVKDGHLCP ALAKAVKTMK KGEKVLLAVK PQYGFGEMGR PAAGEGGAVP
260 270 280 290 300
PNASLVIDLE LVSWKTVTEI GDDKKILKKV LKEXEGYERP NEGAVVTVKI
310 320 330 340 350
TGKLQDGTVF LKKGHDEQEP FEFKTDEEAV IEGLDRAVLN MKKGEVALVT
360 370 380 390 400
IPPEYAYGST ESKQDAIVPP NSTVIYEVEL VSFVKDKESW DLNNSEKIEA
410 420 430 440 450
AGTKKEEGNA LFKSGKYARA SKRYEKAAKF IEYDTSFSED EKKQSKQLKI
460 470 480 490 500
TCNLNNAACK LKLKDYKQAE KLCTKVLELD SRNVKALYRR AQAYTQLADL
510 520 530 540 550
ELAEVDIKKA LEIDPENRDV KLTYKTLKEK IKEINKKDAK FYSNMFSKMT

KPSAEESKA
Length:559
Mass (Da):62,058
Last modified:November 1, 1996 - v1
Checksum:i5C5DAE70D716B541
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X86903 mRNA. Translation: CAA60505.1.
PIRiS55383.
UniGeneiTa.55812.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X86903 mRNA. Translation: CAA60505.1 .
PIRi S55383.
UniGenei Ta.55812.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3JXV X-ray 2.08 A 31-386 [» ]
3JYM X-ray 2.28 A/B 15-391 [» ]
ProteinModelPortali Q43207.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

Gramenei Q43207.

Miscellaneous databases

EvolutionaryTracei Q43207.

Family and domain databases

Gene3Di 1.25.40.10. 1 hit.
InterProi IPR023566. PPIase_FKBP.
IPR001179. PPIase_FKBP_dom.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR001440. TPR_1.
IPR013105. TPR_2.
IPR019734. TPR_repeat.
[Graphical view ]
PANTHERi PTHR10516. PTHR10516. 1 hit.
Pfami PF00254. FKBP_C. 3 hits.
PF00515. TPR_1. 2 hits.
PF07719. TPR_2. 1 hit.
[Graphical view ]
SMARTi SM00028. TPR. 3 hits.
[Graphical view ]
PROSITEi PS50059. FKBP_PPIASE. 3 hits.
PS50005. TPR. 3 hits.
PS50293. TPR_REGION. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Wheat FKBP70 - a novel heat shock and calmodulin binding PPIase."
    Oshra B., Breiman A.
    Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Atir.
    Tissue: Root tip.

Entry informationi

Entry nameiFKB70_WHEAT
AccessioniPrimary (citable) accession number: Q43207
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: November 26, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3