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Q43188

- CHS2_SOLTU

UniProt

Q43188 - CHS2_SOLTU

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Protein

Chalcone synthase 2

Gene
CHS2
Organism
Solanum tuberosum (Potato)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641 By similarity

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase 2 (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase 2
Gene namesi
Name:CHS2
OrganismiSolanum tuberosum (Potato)
Taxonomic identifieri4113 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum
ProteomesiUP000011115: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 389389Chalcone synthase 2PRO_0000216054Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ43188.
SMRiQ43188. Positions 3-388.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00660.

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q43188-1 [UniParc]FASTAAdd to Basket

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MVTVEEVRKA QRAKGPATIM AIGTATPSNC VDQSTYPDYY FRITNSEHMT    50
ELKEKFKRMC DKSMINKRYM HLTEEILKEN PNICEYMAPS LDARQDIVVV 100
EVPKLGKEAA QKAIKEWGQP KSKITHVVFC TTSGVDMPGA DYQLTKLLGL 150
RPSVKRLMMY QQGCFAGGTV IRLAKDLAEN NKGARVLVVC SEITAVTFSG 200
PSDTHLDSMV GQALFGDGAA AMIIGSDPLP EVERPLFELV SAAQTLLPDS 250
EGAIDGHLRE VGLTFHLLKD VPGLISKNIE KSLIEAFQPL GISDWNSIFW 300
IAHPGGPAIL DQVELKLGLK PEKLQATRQV LSDYGNMSSA CVLFILDEMR 350
KASSKEGLST TGEGLDWGVL FGFGPGLTVE TVVLHSVST 389
Length:389
Mass (Da):42,476
Last modified:November 1, 1996 - v1
Checksum:i41618F9944958603
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U47738 mRNA. Translation: AAB05239.1.
PIRiJC5136.
RefSeqiNP_001275296.1. NM_001288367.1.
UniGeneiStu.18497.

Genome annotation databases

GeneIDi102577598.
KEGGisot:102577598.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U47738 mRNA. Translation: AAB05239.1 .
PIRi JC5136.
RefSeqi NP_001275296.1. NM_001288367.1.
UniGenei Stu.18497.

3D structure databases

ProteinModelPortali Q43188.
SMRi Q43188. Positions 3-388.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 102577598.
KEGGi sot:102577598.

Phylogenomic databases

KOi K00660.

Enzyme and pathway databases

UniPathwayi UPA00154 .

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning and characterization of one member of the chalcone synthase gene family from Solanum tuberosum L."
    Jeon J.-H., Kim H.S., Choi K.H., Joung Y.H., Joung H., Byun S.-M.
    Biosci. Biotechnol. Biochem. 60:1907-1910(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Red Pontiac.

Entry informationi

Entry nameiCHS2_SOLTU
AccessioniPrimary (citable) accession number: Q43188
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1996
Last modified: September 3, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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