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Q43188

- CHS2_SOLTU

UniProt

Q43188 - CHS2_SOLTU

Protein

Chalcone synthase 2

Gene

CHS2

Organism
Solanum tuberosum (Potato)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

    Catalytic activityi

    3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei164 – 1641PROSITE-ProRule annotation

    GO - Molecular functioni

    1. naringenin-chalcone synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. flavonoid biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Keywords - Biological processi

    Flavonoid biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00154.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chalcone synthase 2 (EC:2.3.1.74)
    Alternative name(s):
    Naringenin-chalcone synthase 2
    Gene namesi
    Name:CHS2
    OrganismiSolanum tuberosum (Potato)
    Taxonomic identifieri4113 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum
    ProteomesiUP000011115: Unplaced

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 389389Chalcone synthase 2PRO_0000216054Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ43188.
    SMRiQ43188. Positions 3-388.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the chalcone/stilbene synthases family.Curated

    Phylogenomic databases

    KOiK00660.

    Family and domain databases

    Gene3Di3.40.47.10. 2 hits.
    InterProiIPR012328. Chalcone/stilbene_synth_C.
    IPR018088. Chalcone/stilbene_synthase_AS.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011141. Polyketide_synthase_type-III.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view]
    PfamiPF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000451. PKS_III. 1 hit.
    SUPFAMiSSF53901. SSF53901. 2 hits.
    PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q43188-1 [UniParc]FASTAAdd to Basket

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    MVTVEEVRKA QRAKGPATIM AIGTATPSNC VDQSTYPDYY FRITNSEHMT    50
    ELKEKFKRMC DKSMINKRYM HLTEEILKEN PNICEYMAPS LDARQDIVVV 100
    EVPKLGKEAA QKAIKEWGQP KSKITHVVFC TTSGVDMPGA DYQLTKLLGL 150
    RPSVKRLMMY QQGCFAGGTV IRLAKDLAEN NKGARVLVVC SEITAVTFSG 200
    PSDTHLDSMV GQALFGDGAA AMIIGSDPLP EVERPLFELV SAAQTLLPDS 250
    EGAIDGHLRE VGLTFHLLKD VPGLISKNIE KSLIEAFQPL GISDWNSIFW 300
    IAHPGGPAIL DQVELKLGLK PEKLQATRQV LSDYGNMSSA CVLFILDEMR 350
    KASSKEGLST TGEGLDWGVL FGFGPGLTVE TVVLHSVST 389
    Length:389
    Mass (Da):42,476
    Last modified:November 1, 1996 - v1
    Checksum:i41618F9944958603
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U47738 mRNA. Translation: AAB05239.1.
    PIRiJC5136.
    RefSeqiNP_001275296.1. NM_001288367.1.
    UniGeneiStu.18497.

    Genome annotation databases

    GeneIDi102577598.
    KEGGisot:102577598.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U47738 mRNA. Translation: AAB05239.1 .
    PIRi JC5136.
    RefSeqi NP_001275296.1. NM_001288367.1.
    UniGenei Stu.18497.

    3D structure databases

    ProteinModelPortali Q43188.
    SMRi Q43188. Positions 3-388.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 102577598.
    KEGGi sot:102577598.

    Phylogenomic databases

    KOi K00660.

    Enzyme and pathway databases

    UniPathwayi UPA00154 .

    Family and domain databases

    Gene3Di 3.40.47.10. 2 hits.
    InterProi IPR012328. Chalcone/stilbene_synth_C.
    IPR018088. Chalcone/stilbene_synthase_AS.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011141. Polyketide_synthase_type-III.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view ]
    Pfami PF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000451. PKS_III. 1 hit.
    SUPFAMi SSF53901. SSF53901. 2 hits.
    PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and characterization of one member of the chalcone synthase gene family from Solanum tuberosum L."
      Jeon J.-H., Kim H.S., Choi K.H., Joung Y.H., Joung H., Byun S.-M.
      Biosci. Biotechnol. Biochem. 60:1907-1910(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Red Pontiac.

    Entry informationi

    Entry nameiCHS2_SOLTU
    AccessioniPrimary (citable) accession number: Q43188
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1999
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3