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Q43175

- CISY_SOLTU

UniProt

Q43175 - CISY_SOLTU

Protein

Citrate synthase, mitochondrial

Gene
N/A
Organism
Solanum tuberosum (Potato)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Acetyl-CoA + H2O + oxaloacetate = citrate + CoA.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei309 – 3091PROSITE-ProRule annotation
    Active sitei355 – 3551PROSITE-ProRule annotation
    Active sitei409 – 4091PROSITE-ProRule annotation

    GO - Molecular functioni

    1. citrate (Si)-synthase activity Source: InterPro

    GO - Biological processi

    1. cellular carbohydrate metabolic process Source: InterPro
    2. tricarboxylic acid cycle Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Tricarboxylic acid cycle

    Enzyme and pathway databases

    UniPathwayiUPA00223; UER00717.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Citrate synthase, mitochondrial (EC:2.3.3.16)
    OrganismiSolanum tuberosum (Potato)
    Taxonomic identifieri4113 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum
    ProteomesiUP000011115: Unplaced

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrial matrix Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Mitochondrion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini? – 471Citrate synthase, mitochondrialPRO_0000005489
    Transit peptidei1 – ?MitochondrionSequence Analysis

    Proteomic databases

    PRIDEiQ43175.

    Expressioni

    Tissue specificityi

    Ubiquitous.

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ43175.
    SMRiQ43175. Positions 39-469.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the citrate synthase family.Curated

    Keywords - Domaini

    Transit peptide

    Family and domain databases

    Gene3Di1.10.580.10. 1 hit.
    InterProiIPR016142. Citrate_synth-like_lrg_a-sub.
    IPR002020. Citrate_synthase-like.
    IPR016141. Citrate_synthase-like_core.
    IPR019810. Citrate_synthase_AS.
    IPR010109. Citrate_synthase_euk.
    [Graphical view]
    PANTHERiPTHR11739. PTHR11739. 1 hit.
    PfamiPF00285. Citrate_synt. 1 hit.
    [Graphical view]
    PRINTSiPR00143. CITRTSNTHASE.
    SUPFAMiSSF48256. SSF48256. 1 hit.
    TIGRFAMsiTIGR01793. cit_synth_euk. 1 hit.
    PROSITEiPS00480. CITRATE_SYNTHASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q43175-1 [UniParc]FASTAAdd to Basket

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    MVFYRSVSLL SKLRSRAVQQ SNVSNSVRWL QVQTSSGLDL RSELVQELIP    50
    EQQDRLKKIK SDMKGSIGNI TVDMVLGGMR GMTGLLWKPH YLDPDEGIRF 100
    RGLSIPECQK VLPAAKPGGE PLPEGLLWLL LTGKVPSKEQ VNSIVSGIAE 150
    SGIISLIIMY TTIDALPVTA HPMTQFATGV MALQVQSEFQ KAYEKGIHKS 200
    KYWEPTYEDS MNLIAQVPLV AAYVYRRMYK NGDTIPKDES LDYGANFAHM 250
    LGFSSSEMHE LLMRLYVTIH SDHEGGNVSA HTGHLVASAL SDPYLSFAAA 300
    LNGLAGPLHG LANQEVLLWI KSVVEECGEN ISKEQLKDYV WKTLNSGKVV 350
    PGFGHGVLRK TVPRYTCQRE FAMKHLPEDP LFQLVSKLYE VFLLFLQNLA 400
    KLKPWPNVDA HSGVLLNYYG LTEARYYTVL FGVSRALGIC SQLIWDRALG 450
    LPLERPKSVT MEWLENQCKK A 471
    Length:471
    Mass (Da):52,612
    Last modified:November 1, 1996 - v1
    Checksum:iBC6B5673792564C6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X75082 mRNA. Translation: CAA52976.1.
    PIRiS44316.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X75082 mRNA. Translation: CAA52976.1 .
    PIRi S44316.

    3D structure databases

    ProteinModelPortali Q43175.
    SMRi Q43175. Positions 39-469.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q43175.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00223 ; UER00717 .

    Family and domain databases

    Gene3Di 1.10.580.10. 1 hit.
    InterProi IPR016142. Citrate_synth-like_lrg_a-sub.
    IPR002020. Citrate_synthase-like.
    IPR016141. Citrate_synthase-like_core.
    IPR019810. Citrate_synthase_AS.
    IPR010109. Citrate_synthase_euk.
    [Graphical view ]
    PANTHERi PTHR11739. PTHR11739. 1 hit.
    Pfami PF00285. Citrate_synt. 1 hit.
    [Graphical view ]
    PRINTSi PR00143. CITRTSNTHASE.
    SUPFAMi SSF48256. SSF48256. 1 hit.
    TIGRFAMsi TIGR01793. cit_synth_euk. 1 hit.
    PROSITEi PS00480. CITRATE_SYNTHASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Mitochondrial citrate synthase from potato: predominant expression in mature leaves and young flower buds."
      Landschuetze V., Willmitzer L., Mueller-Roeber B.
      Planta 196:756-764(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Desiree.

    Entry informationi

    Entry nameiCISY_SOLTU
    AccessioniPrimary (citable) accession number: Q43175
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Citrate synthase is found in nearly all cells capable of oxidative metabolism.

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3