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Q43175

- CISY_SOLTU

UniProt

Q43175 - CISY_SOLTU

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Protein

Citrate synthase, mitochondrial

Gene
N/A
Organism
Solanum tuberosum (Potato)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Acetyl-CoA + H2O + oxaloacetate = citrate + CoA.PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei309 – 3091PROSITE-ProRule annotation
Active sitei355 – 3551PROSITE-ProRule annotation
Active sitei409 – 4091PROSITE-ProRule annotation

GO - Molecular functioni

  1. citrate (Si)-synthase activity Source: InterPro

GO - Biological processi

  1. cellular carbohydrate metabolic process Source: InterPro
  2. tricarboxylic acid cycle Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Tricarboxylic acid cycle

Enzyme and pathway databases

UniPathwayiUPA00223; UER00717.

Names & Taxonomyi

Protein namesi
Recommended name:
Citrate synthase, mitochondrial (EC:2.3.3.16)
OrganismiSolanum tuberosum (Potato)
Taxonomic identifieri4113 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum
ProteomesiUP000011115: Unplaced

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini? – 471Citrate synthase, mitochondrialPRO_0000005489
Transit peptidei1 – ?MitochondrionSequence Analysis

Proteomic databases

PRIDEiQ43175.

Expressioni

Tissue specificityi

Ubiquitous.

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ43175.
SMRiQ43175. Positions 39-469.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the citrate synthase family.Curated

Keywords - Domaini

Transit peptide

Family and domain databases

Gene3Di1.10.580.10. 1 hit.
InterProiIPR016142. Citrate_synth-like_lrg_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR010109. Citrate_synthase_euk.
[Graphical view]
PANTHERiPTHR11739. PTHR11739. 1 hit.
PfamiPF00285. Citrate_synt. 1 hit.
[Graphical view]
PRINTSiPR00143. CITRTSNTHASE.
SUPFAMiSSF48256. SSF48256. 1 hit.
TIGRFAMsiTIGR01793. cit_synth_euk. 1 hit.
PROSITEiPS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q43175-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVFYRSVSLL SKLRSRAVQQ SNVSNSVRWL QVQTSSGLDL RSELVQELIP
60 70 80 90 100
EQQDRLKKIK SDMKGSIGNI TVDMVLGGMR GMTGLLWKPH YLDPDEGIRF
110 120 130 140 150
RGLSIPECQK VLPAAKPGGE PLPEGLLWLL LTGKVPSKEQ VNSIVSGIAE
160 170 180 190 200
SGIISLIIMY TTIDALPVTA HPMTQFATGV MALQVQSEFQ KAYEKGIHKS
210 220 230 240 250
KYWEPTYEDS MNLIAQVPLV AAYVYRRMYK NGDTIPKDES LDYGANFAHM
260 270 280 290 300
LGFSSSEMHE LLMRLYVTIH SDHEGGNVSA HTGHLVASAL SDPYLSFAAA
310 320 330 340 350
LNGLAGPLHG LANQEVLLWI KSVVEECGEN ISKEQLKDYV WKTLNSGKVV
360 370 380 390 400
PGFGHGVLRK TVPRYTCQRE FAMKHLPEDP LFQLVSKLYE VFLLFLQNLA
410 420 430 440 450
KLKPWPNVDA HSGVLLNYYG LTEARYYTVL FGVSRALGIC SQLIWDRALG
460 470
LPLERPKSVT MEWLENQCKK A
Length:471
Mass (Da):52,612
Last modified:November 1, 1996 - v1
Checksum:iBC6B5673792564C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X75082 mRNA. Translation: CAA52976.1.
PIRiS44316.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X75082 mRNA. Translation: CAA52976.1 .
PIRi S44316.

3D structure databases

ProteinModelPortali Q43175.
SMRi Q43175. Positions 39-469.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q43175.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00223 ; UER00717 .

Family and domain databases

Gene3Di 1.10.580.10. 1 hit.
InterProi IPR016142. Citrate_synth-like_lrg_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR010109. Citrate_synthase_euk.
[Graphical view ]
PANTHERi PTHR11739. PTHR11739. 1 hit.
Pfami PF00285. Citrate_synt. 1 hit.
[Graphical view ]
PRINTSi PR00143. CITRTSNTHASE.
SUPFAMi SSF48256. SSF48256. 1 hit.
TIGRFAMsi TIGR01793. cit_synth_euk. 1 hit.
PROSITEi PS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Mitochondrial citrate synthase from potato: predominant expression in mature leaves and young flower buds."
    Landschuetze V., Willmitzer L., Mueller-Roeber B.
    Planta 196:756-764(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Desiree.

Entry informationi

Entry nameiCISY_SOLTU
AccessioniPrimary (citable) accession number: Q43175
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

Citrate synthase is found in nearly all cells capable of oxidative metabolism.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3