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Q43128 (PMA10_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 99. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
ATPase 10, plasma membrane-type
EC=3.6.3.6
Alternative name(s):
Proton pump 10
Gene names
Name:AHA10
Ordered Locus Names:At1g17260
ORF Names:F20D23.4
OrganismArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length947 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

The plasma membrane H+ ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H+-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.

Catalytic activity

ATP + H2O + H+(In) = ADP + phosphate + H+(Out).

Subcellular location

Membrane; Multi-pass membrane protein.

Tissue specificity

Found primarily in developing seeds.

Sequence similarities

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. [View classification]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 947947ATPase 10, plasma membrane-type
PRO_0000046283

Regions

Topological domain1 – 6969Cytoplasmic Potential
Transmembrane70 – 8920Helical; Name=1; Potential
Topological domain90 – 10112Extracellular Potential
Transmembrane102 – 12221Helical; Name=2; Potential
Topological domain123 – 251129Cytoplasmic Potential
Transmembrane252 – 27221Helical; Name=3; Potential
Topological domain273 – 2819Extracellular Potential
Transmembrane282 – 29918Helical; Name=4; Potential
Topological domain300 – 650351Cytoplasmic Potential
Transmembrane651 – 67222Helical; Name=5; Potential
Topological domain673 – 6775Extracellular Potential
Transmembrane678 – 70023Helical; Name=6; Potential
Topological domain701 – 71616Cytoplasmic Potential
Transmembrane717 – 73721Helical; Name=7; Potential
Topological domain738 – 75821Extracellular Potential
Transmembrane759 – 77921Helical; Name=8; Potential
Topological domain780 – 79112Cytoplasmic Potential
Transmembrane792 – 81221Helical; Name=9; Potential
Topological domain813 – 8208Extracellular Potential
Transmembrane821 – 84121Helical; Name=10; Potential
Topological domain842 – 947106Cytoplasmic Potential

Sites

Active site33714-aspartylphosphate intermediate By similarity
Metal binding5951Magnesium By similarity
Metal binding5991Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q43128 [UniParc].

Last modified January 24, 2001. Version 2.
Checksum: 1E951DFCC0DA5C24

FASTA947104,815
        10         20         30         40         50         60 
MAEDLDKPLL DPDTFNRKGI DLGILPLEEV FEYLRTSPQG LLSGDAEERL KIFGPNRLEE 

        70         80         90        100        110        120 
KQENRFVKFL GFMWNPLSWV MEAAALMAIA LANSQSLGPD WEDFTGIVCL LLINATISFF 

       130        140        150        160        170        180 
EENNAGNAAA ALMARLALKT RVLRDGQWQE QDASILVPGD IISIKLGDII PADARLLEGD 

       190        200        210        220        230        240 
PLKIDQSVLT GESLPVTKKK GEQVFSGSTC KQGEIEAVVI ATGSTTFFGK TARLVDSTDV 

       250        260        270        280        290        300 
TGHFQQVLTS IGNFCICSIA VGMVLEIIIM FPVQHRSYRI GINNLLVLLI GGIPIAMPTV 

       310        320        330        340        350        360 
LSVTLAIGSH RLSQQGAITK RMTAIEEMAG MDVLCCDKTG TLTLNSLTVD KNLIEVFVDY 

       370        380        390        400        410        420 
MDKDTILLLA GRASRLENQD AIDAAIVSML ADPREARANI REIHFLPFNP VDKRTAITYI 

       430        440        450        460        470        480 
DSDGKWYRAT KGAPEQVLNL CQQKNEIAQR VYAIIDRFAE KGLRSLAVAY QEIPEKSNNS 

       490        500        510        520        530        540 
PGGPWRFCGL LPLFDPPRHD SGETILRALS LGVCVKMITG DQLAIAKETG RRLGMGTNMY 

       550        560        570        580        590        600 
PSSSLLGHNN DEHEAIPVDE LIEMADGFAG VFPEHKYEIV KILQEMKHVV GMTGDGVNDA 

       610        620        630        640        650        660 
PALKKADIGI AVADATDAAR SSADIVLTDP GLSVIISAVL TSRAIFQRMR NYTVYAVSIT 

       670        680        690        700        710        720 
IRIVLGFTLL ALIWEYDFPP FMVLIIAILN DGTIMTISKD RVRPSPTPES WKLNQIFATG 

       730        740        750        760        770        780 
IVIGTYLALV TVLFYWIIVS TTFFEKHFHV KSIANNSEQV SSAMYLQVSI ISQALIFVTR 

       790        800        810        820        830        840 
SRGWSFFERP GTLLIFAFIL AQLAATLIAV YANISFAKIT GIGWRWAGVI WLYSLIFYIP 

       850        860        870        880        890        900 
LDVIKFVFHY ALSGEAWNLV LDRKTAFTYK KDYGKDDGSP NVTISQRSRS AEELRGSRSR 

       910        920        930        940 
ASWIAEQTRR RAEIARLLEV HSVSRHLESV IKLKQIDQRM IRAAHTV

« Hide

References

« Hide 'large scale' references
[1]"The plasma membrane H(+)-ATPase gene family in Arabidopsis: genomic sequence of AHA10 which is expressed primarily in developing seeds."
Harper J.F., Manney L., Sussman M.R.
Mol. Gen. Genet. 244:572-587(1994) [PubMed: 7969026] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. Columbia.
[2]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed: 11130712] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		S74033 Genomic DNA. Translation: AAB32310.2.
AC007651 Genomic DNA. Translation: AAD50009.3.
CP002684 Genomic DNA. Translation: AEE29565.1.
IPIIPI00539488.
PIRS66367.
RefSeqNP_173169.2. NM_101587.2.
UniGeneAt.51646.

3D structure databases

ProteinModelPortalQ43128.
SMRQ43128. Positions 20-947.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ43128.

Proteomic databases

PRIDEQ43128.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G17260.1; AT1G17260.1; AT1G17260.
GeneID838297.
GenomeReviewsGene locus AT1G17260 in contig CT485782_GR.
KEGGath:AT1G17260.
NMPDRfig|3702.1.peg.2047.

Organism-specific databases

TAIRAt1g17260.

Phylogenomic databases

eggNOGKOG0205.
GeneTreeEPGT00050000005325.
HOGENOMHBG706356.
InParanoidQ43128.
OMAFCGLLPL.
PhylomeDBQ43128.

Gene expression databases

ArrayExpressQ43128.
GenevestigatorQ43128.
GermOnlineAT1G17260. Arabidopsis thaliana.

Family and domain databases

InterProIPR008250. ATPase_P-typ_ATPase-assoc-dom.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR023300. ATPase_P-typ_cyto_domA.
IPR023299. ATPase_P-typ_cyto_domN.
IPR000695. ATPase_P-typ_H-transp.
IPR001757. ATPase_P-typ_ion-transptr.
IPR018303. ATPase_P-typ_P_site.
IPR006534. ATPase_P-typ_PM_proton-efflux.
IPR023298. ATPase_P-typ_TM_dom.
IPR005834. Dehalogen-like_hydro.
IPR023214. HAD-like_dom.
[Graphical view]
Gene3DG3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 2 hits.
G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 1 hit.
G3DSA:1.20.1110.10. ATPase_P-typ_TM_dom. 3 hits.
KOK01535.
PANTHERPTHR24093:SF61. PTHR24093:SF61. 1 hit.
PfamPF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
PF00702. Hydrolase. 1 hit.
[Graphical view]
PRINTSPR00119. CATATPASE.
PR00120. HATPASE.
SMARTSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
SUPFAMSSF56784. HAD-like_dom. 1 hit.
TIGRFAMsTIGR01647. ATPase-IIIA_H. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePMA10_ARATH
AccessionPrimary (citable) accession number: Q43128
Entry history
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: January 24, 2001
Last modified: November 16, 2011
This is version 99 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents