##gff-version 3
Q43116	UniProtKB	Signal peptide	1	23	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q43116	UniProtKB	Chain	24	498	.	.	.	ID=PRO_0000034211;Note=Protein disulfide-isomerase	
Q43116	UniProtKB	Domain	24	143	.	.	.	Note=Thioredoxin 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00691	
Q43116	UniProtKB	Domain	339	484	.	.	.	Note=Thioredoxin 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00691	
Q43116	UniProtKB	Motif	495	498	.	.	.	Note=Prevents secretion from ER;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU10138	
Q43116	UniProtKB	Active site	61	61	.	.	.	Note=Nucleophile;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q43116	UniProtKB	Active site	64	64	.	.	.	Note=Nucleophile;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q43116	UniProtKB	Active site	406	406	.	.	.	Note=Nucleophile;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q43116	UniProtKB	Active site	409	409	.	.	.	Note=Nucleophile;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q43116	UniProtKB	Site	62	62	.	.	.	Note=Contributes to redox potential value;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q43116	UniProtKB	Site	63	63	.	.	.	Note=Contributes to redox potential value;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q43116	UniProtKB	Site	129	129	.	.	.	Note=Lowers pKa of C-terminal Cys of first active site;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q43116	UniProtKB	Site	407	407	.	.	.	Note=Contributes to redox potential value;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q43116	UniProtKB	Site	408	408	.	.	.	Note=Contributes to redox potential value;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q43116	UniProtKB	Site	470	470	.	.	.	Note=Lowers pKa of C-terminal Cys of second active site;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q43116	UniProtKB	Glycosylation	41	41	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q43116	UniProtKB	Disulfide bond	61	64	.	.	.	Note=Redox-active;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00691	
Q43116	UniProtKB	Disulfide bond	406	409	.	.	.	Note=Redox-active;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00691