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Q43097

- ACEA_PINTA

UniProt

Q43097 - ACEA_PINTA

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Protein
Isocitrate lyase
Gene
ICL 8
Organism
Pinus taeda (Loblolly pine)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Involved in storage lipid mobilization during the growth of higher plant seedling.

Catalytic activityi

Isocitrate = succinate + glyoxylate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei215 – 2151 Inferred

GO - Molecular functioni

  1. isocitrate lyase activity Source: UniProtKB-EC

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-UniPathway
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Glyoxylate bypass, Tricarboxylic acid cycle

Enzyme and pathway databases

UniPathwayiUPA00703; UER00719.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate lyase (EC:4.1.3.1)
Short name:
ICL
Short name:
Isocitrase
Short name:
Isocitratase
Gene namesi
Name:ICL 8
OrganismiPinus taeda (Loblolly pine)
Taxonomic identifieri3352 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaPinidaePinalesPinaceaePinusPinus

Subcellular locationi

GO - Cellular componenti

  1. glyoxysome Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Glyoxysome, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 580580Isocitrate lyase
PRO_0000068809Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.

Structurei

3D structure databases

ProteinModelPortaliQ43097.
SMRiQ43097. Positions 11-539.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi578 – 5803Microbody targeting signal Reviewed prediction

Sequence similaritiesi

Family and domain databases

Gene3Di3.20.20.60. 2 hits.
InterProiIPR006254. Isocitrate_lyase.
IPR018523. Isocitrate_lyase_ph_CS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PANTHERiPTHR21631:SF3. PTHR21631:SF3. 1 hit.
PfamiPF00463. ICL. 1 hit.
[Graphical view]
PIRSFiPIRSF001362. Isocit_lyase. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR01346. isocit_lyase. 1 hit.
PROSITEiPS00161. ISOCITRATE_LYASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q43097-1 [UniParc]FASTAAdd to Basket

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MAIYSAQAPN SILEEEARFE AEVSETQAWW NSTDLFRLTR RPYTARDVVR    50
LRGSMRQSYA SNEMAKKLWR TLKTHQANKT ASRTFGALDP VQVSMMAKYL 100
DSIYVSGWQC SSTHTTTNEP GPDLADYPYD TVPNKVEHLF FAQQFHDRKQ 150
KEARMSMTRE ERSKTPYIDY LKPIIADGDT GFGGATATVK LCKLFVERGA 200
AGVHIEDQAS VTKKCGHMAG KVLVSVGEHV NRMVAARLQF DIMGVETLLV 250
ARTDAVAATL IQTNVDARDH QFILGATNPN LKGKPLADVL ARAMASGKSG 300
ADLQAVEDEW MAMADLKLFS DCVVDGIKAL NVSEQEKGRR LGEWMQQTGG 350
NTGNVLSYYQ AKELAEKLGI SNLFWDWDLP RTREGFYRFQ GSVKAAIVRG 400
WAFGPHADII WMETSSPDMV ECRDFALGVK SKHPEIMLAY NLSPSFNWDA 450
SRMTDEQMKN FIPEIARLGY CWQFITLAGF HADALVIDTF AKDFAQRGML 500
AYVEKIQRQE MMNGVDTLAH QKWSGANYYD QLLKTVQGGI SATAAMAKGV 550
TEDQFEETQS STLALESNIG AGTVLAKSRM 580
Length:580
Mass (Da):64,676
Last modified:November 1, 1996 - v1
Checksum:iE85785DAE970D697
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U39807 mRNA. Translation: AAC49687.1.
PIRiT09779.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U39807 mRNA. Translation: AAC49687.1 .
PIRi T09779.

3D structure databases

ProteinModelPortali Q43097.
SMRi Q43097. Positions 11-539.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00703 ; UER00719 .

Family and domain databases

Gene3Di 3.20.20.60. 2 hits.
InterProi IPR006254. Isocitrate_lyase.
IPR018523. Isocitrate_lyase_ph_CS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
PANTHERi PTHR21631:SF3. PTHR21631:SF3. 1 hit.
Pfami PF00463. ICL. 1 hit.
[Graphical view ]
PIRSFi PIRSF001362. Isocit_lyase. 1 hit.
SUPFAMi SSF51621. SSF51621. 1 hit.
TIGRFAMsi TIGR01346. isocit_lyase. 1 hit.
PROSITEi PS00161. ISOCITRATE_LYASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Regulation of two loblolly pine (Pinus taeda L.) isocitrate lyase genes in megagametophytes of mature and stratified seeds and during postgerminative growth."
    Mullen R.T., Gifford D.J.
    Plant Mol. Biol. 33:593-604(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiACEA_PINTA
AccessioniPrimary (citable) accession number: Q43097
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: May 14, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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