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Q43075 (SPE1_PEA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine decarboxylase

Short name=ADC
Short name=ARGDC
EC=4.1.1.19
OrganismPisum sativum (Garden pea)
Taxonomic identifier3888 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaePisum

Protein attributes

Sequence length728 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

L-arginine = agmatine + CO2.

Cofactor

Pyridoxal phosphate.

Magnesium.

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 728728Arginine decarboxylase
PRO_0000149953

Regions

Region345 – 35511Substrate-binding By similarity

Amino acid modifications

Modified residue1611N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q43075 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 4193A30AEAD8EC4C

FASTA72878,710
        10         20         30         40         50         60 
MPALTCFVDG AAALLHPPGY ALAGDFTLPL PFTFSAAATI TDDADATAVE DSNSIWSPSL 

        70         80         90        100        110        120 
SSKLFRIDGW GFPYFGVNAA GDISVRPHGS ATMSHQEIDL LKVVKKASDP KCCGGLGLQL 

       130        140        150        160        170        180 
PLVVRFPDVL KDRLESIHAA FDGAIQLQGY ESHYQGVYPV KCNQDRYIVE DIVEFGSSFR 

       190        200        210        220        230        240 
FGLEAGSKPE LLLAMSCLCK GNREAFLVCN GFKDSEYISL ALIARKLALN TVIVLEQEEE 

       250        260        270        280        290        300 
LDMVVEISNK LCIRPVIGVR AKLKTKHSGH FGATSGDKGK FGLTTIQILH VVKKLEQLDM 

       310        320        330        340        350        360 
LDCLQLLHFH IGSQIPTTEL LADGVREASQ IYCELLRLGA QMKVLDIGGG LGIDYDGSKS 

       370        380        390        400        410        420 
GDSDESVAYG LEEYAAAVVH AVKYVCDRKN VKHPVICSES GRAIVSHHSI LIFEASGAST 

       430        440        450        460        470        480 
NTAPSLSSIE LQYLGEGLSE EALADYQNIS AATLRGEYEA CLLYTEQFKK RCVEEFKQGT 

       490        500        510        520        530        540 
LGIEQLAAVD GLCDLITETI GVKDPVKKYH VNLSVFTSVP DFWGINQLFP IVPIHRLDEK 

       550        560        570        580        590        600 
PTARGILSDL TCDSDGKIDK FIGGESSLPL HEMEGHGGGY YLGMFLGGSY EEALGGLHNL 

       610        620        630        640        650        660 
FGGPSVVRVL QSDGPHGFAV TRAVAGSSCA DVLRVMQHEP QLMFETLKHR ALEFCGQHDD 

       670        680        690        700        710        720 
DSVVNAGVLA NSLAQSFDNM PYLVSSTTCC LNALTNNNGF YYCSGDDFSA DTVSVATSVA 


GEDENWSY 

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References

[1]"Expression of arginine decarboxylase is induced during early fruit development and in young tissues of Pisum sativum (L.)."
Perez-Amador M.A., Carbonell J., Granell A.
Plant Mol. Biol. 28:997-1009(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z37540 mRNA. Translation: CAA85773.1.
PIRS59553.

3D structure databases

ProteinModelPortalQ43075.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-14984.
UniPathwayUPA00186; UER00284.

Family and domain databases

Gene3D2.40.37.10. 2 hits.
3.20.20.10. 1 hit.
InterProIPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022657. De-COase2_CS.
IPR022644. De-COase2_N.
IPR022653. De-COase2_pyr-phos_BS.
IPR000183. Orn/DAP/Arg_de-COase.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR01273. speA. 1 hit.
PROSITEPS00878. ODR_DC_2_1. 1 hit.
PS00879. ODR_DC_2_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPE1_PEA
AccessionPrimary (citable) accession number: Q43075
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: June 11, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways