Reviewed, UniProtKB/Swiss-Prot Q43070 (GALE1_PEA)

Names and origin

Protein names

Recommended name:
    UDP-glucose 4-epimerase
    EC=5.1.3.2
Alternative name(s):
    UDP-galactose 4-epimerase
    Galactowaldenase

Gene names

Name:

GALE

Organism

Pisum sativum (Garden pea)

Taxonomic identifier

3888 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids I › Fabales › Fabaceae › Papilionoideae › Fabeae › Pisum

Protein attributes

Sequence length	350 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	UDP-glucose = UDP-galactose.
Cofactor	NAD By similarity.
Pathway	Carbohydrate metabolism; galactose metabolism.
Sequence similarities	Belongs to the sugar epimerase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Galactose metabolism
Ligand	NAD
Molecular function	Isomerase
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-glucose 4-epimerase activity Inferred from electronic annotation. Source: EC coenzyme binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 350	350	UDP-glucose 4-epimerase		PRO_0000183198
Regions
	Nucleotide binding	7 – 38	32	NAD By similarity
Sites
	Active site	157	1	Proton acceptor By similarity
	Binding site	133	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q43070-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 86CB3444C9BDCFAC	FASTA	350	38,990
	10 20 30 40 50 60 MVASSQKILV TGSAGFIGTH TVVQLLNNGF NVSIIDNFDN SVMEAVERVR EVVGSNLSQN 70 80 90 100 110 120 LEFTLGDLRN KDDLEKLFSK SKFDAVIHFA GLKAVGESVE NPRRYFDNNL VGTINLYEVM 130 140 150 160 170 180 AKHNCKKMVF SSSATVYGQP EKIPCVEDFK LQAMNPYGRT KLFLEEIARD IQKAEPEWRI 190 200 210 220 230 240 VLLRYFNPVG AHESGKLGED PRGIPNNLMP YIQQVAVGRL PELNVYGHDY PTRDGSAIRD 250 260 270 280 290 300 YIHVMDLADG HIAALRKLFT SENIGCTAYN LGTGRGSSVL EMVAAFEKAS GKKIALKLCP 310 320 330 340 350 RRPGDATEVY ASTAKAEKEL GWKAKYGVEE MCRDQWNWAK NNPWGYSGKP

References

[1]	"Cloning and characterization of a UDP-galactose-4-epimerase ('galactowaldenase') and its expression in pea tissues." Slocum R.D., Lake M.R., Williamson C.L. Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Wando.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U31544 mRNA. Translation: AAA86532.1.
PIR	T06526.
3D structure databases
HSSP	HSSP built from PDB template 1EK6 based on UniProtKB Q14376.
ModBase	Search...
Enzyme and pathway databases
BRENDA	5.1.3.2. 287.
Family and domain databases
InterPro	IPR001509. Epimerase_deHydtase. IPR005886. GalE. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHER	PTHR10366:SF39. GalE. 1 hit.
Pfam	PF01370. Epimerase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01179. galE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GALE1_PEA

Accession

Primary (citable) accession number: Q43070

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	November 1, 1996
Last modified:	June 16, 2009
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)