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Q43060

- Q43060_PORPP

UniProt

Q43060 - Q43060_PORPP

Protein

Carbonic anhydrase

Gene

gtPCA1

Organism
Porphyridium purpureum (Red alga) (Porphyridium cruentum)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    H2CO3 = CO2 + H2O.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi149 – 1491Zinc 1Imported
    Metal bindingi151 – 1511Zinc 1Imported
    Metal bindingi205 – 2051Zinc 1; via tele nitrogenImported
    Metal bindingi208 – 2081Zinc 1Imported
    Metal bindingi403 – 4031Zinc 2Imported
    Metal bindingi405 – 4051Zinc 2Imported
    Metal bindingi459 – 4591Zinc 2; via tele nitrogenImported
    Metal bindingi462 – 4621Zinc 2Imported

    GO - Molecular functioni

    1. carbonate dehydratase activity Source: UniProtKB-EC
    2. zinc ion binding Source: InterPro

    GO - Biological processi

    1. carbon utilization Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationImported

    Keywords - Ligandi

    Metal-bindingImported, ZincUniRule annotationImported

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Carbonic anhydraseUniRule annotation (EC:4.2.1.1UniRule annotation)
    Gene namesi
    Name:gtPCA1Imported
    Synonyms:pca1Imported
    OrganismiPorphyridium purpureum (Red alga) (Porphyridium cruentum)Imported
    Taxonomic identifieri35688 [NCBI]
    Taxonomic lineageiEukaryotaRhodophytaBangiophyceaePorphyridialesPorphyridiaceaePorphyridium

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1DDZX-ray2.20A/B76-571[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ43060.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the beta-class carbonic anhydrase family.UniRule annotation

    Family and domain databases

    Gene3Di3.40.1050.10. 2 hits.
    InterProiIPR001765. Carbonic_anhydrase.
    IPR015892. Carbonic_anhydrase_CS.
    [Graphical view]
    PANTHERiPTHR11002. PTHR11002. 1 hit.
    PfamiPF00484. Pro_CA. 2 hits.
    [Graphical view]
    SMARTiSM00947. Pro_CA. 2 hits.
    [Graphical view]
    SUPFAMiSSF53056. SSF53056. 2 hits.
    PROSITEiPS00704. PROK_CO2_ANHYDRASE_1. 2 hits.
    PS00705. PROK_CO2_ANHYDRASE_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q43060-1 [UniParc]FASTAAdd to Basket

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    MVQIYNGGAG FERALSRGKS KDGKPKATAA ATAAPAASSS AAPARAAPAR    50
    AAPAAAAPVS KPTAEKPAVA QDATLVKLAA GMGVMSDLEK KFIELEAKLV 100
    AQPAGQAMPG KSNIFANNEA WRQEMLKQDP EFFNRLANGQ SPEYLWIGCA 150
    DSRVPANQLL DLPAGEVFVH RNIANQCIHS DISFLSVLQY AVQYLKVKHI 200
    LVCGHYGCGG AKAALGDSRL GLIDNWLRHI RDVRRMNAKY LDKCKDGDEE 250
    LNRLIELNVL EQVHNVCATS IVQDAWDAGQ ELTVQGVVYG VGDGKLRDLG 300
    VVVNSSDDIS KFYRTKSDSG ALKAGNPNAP LVQVTKGGES ELDSTMEKLT 350
    AELVQQTPGK LKEGANRVFV NNENWRQKML KQDPQFFSNL AHTQTPEILW 400
    IGCADSRVPA NQIINLPAGE VFVHRNIANQ CIHSDMSFLS VLQYAVQYLK 450
    VKRVVVCGHY ACGGCAAALG DSRLGLIDNW LRHIRDVRRH NQAELSRITD 500
    PKDSLNRLIE INVLEQMHNV CATSIVQDAW DAGQELEVQG VVYGVGDGKL 550
    RDMGVVAKAN DDIGQIFRTK Q 571
    Length:571
    Mass (Da):62,095
    Last modified:November 1, 1996 - v1
    Checksum:i05DC7AFFE84F8C87
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D86050 mRNA. Translation: BAA12980.1.
    AB040135 Genomic DNA. Translation: BAA92829.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D86050 mRNA. Translation: BAA12980.1 .
    AB040135 Genomic DNA. Translation: BAA92829.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1DDZ X-ray 2.20 A/B 76-571 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei Q43060.

    Family and domain databases

    Gene3Di 3.40.1050.10. 2 hits.
    InterProi IPR001765. Carbonic_anhydrase.
    IPR015892. Carbonic_anhydrase_CS.
    [Graphical view ]
    PANTHERi PTHR11002. PTHR11002. 1 hit.
    Pfami PF00484. Pro_CA. 2 hits.
    [Graphical view ]
    SMARTi SM00947. Pro_CA. 2 hits.
    [Graphical view ]
    SUPFAMi SSF53056. SSF53056. 2 hits.
    PROSITEi PS00704. PROK_CO2_ANHYDRASE_1. 2 hits.
    PS00705. PROK_CO2_ANHYDRASE_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Amino acid sequence homology between N- and C-terminal halves of a carbonic anhydrase in Porphyridium purpureum, as deduced from the cloned cDNA."
      Mitsuhashi S., Miyachi S.
      J. Biol. Chem. 271:28703-28709(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: IAM-R1Imported.
    2. "Primary structure of a carbonic anhydrase in Porphyridium purpureum, deduced from the clone cDNA. Amino acid sequence homology between N- and C- terminal halves of the enzyme."
      Mitsuhashi S., Miyachi S.
      Submitted (JUN-1996) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: IAM-R1Imported.
    3. "X-ray structure of beta-carbonic anhydrase from the red alga, Porphyridium purpureum, reveals a novel catalytic site for CO(2) hydration."
      Mitsuhashi S., Mizushima T., Yamashita E., Yamamoto M., Kumasaka T., Moriyama H., Ueki T., Miyachi S., Tsukihara T.
      J. Biol. Chem. 275:5521-5526(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 76-571 IN COMPLEX WITH ZINC.
    4. "genomic region coding for a carbonic anhydrase from Porphyridium purpureum."
      Mitsuhashi S.
      Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ43060_PORPP
    AccessioniPrimary (citable) accession number: Q43060
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1996
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 92 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3