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Q42962

- PGKY_TOBAC

UniProt

Q42962 - PGKY_TOBAC

Protein

Phosphoglycerate kinase, cytosolic

Gene
N/A
Organism
Nicotiana tabacum (Common tobacco)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei41 – 411SubstrateBy similarity
    Binding sitei122 – 1221SubstrateBy similarity
    Binding sitei155 – 1551SubstrateBy similarity
    Binding sitei206 – 2061ATPBy similarity
    Binding sitei297 – 2971ATP; via carbonyl oxygenBy similarity
    Binding sitei328 – 3281ATPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi357 – 3604ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinase, cytosolic (EC:2.7.2.3)
    OrganismiNicotiana tabacum (Common tobacco)
    Taxonomic identifieri4097 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 401401Phosphoglycerate kinase, cytosolicPRO_0000145871Add
    BLAST

    Proteomic databases

    PRIDEiQ42962.
    ProMEXiQ42962.

    Interactioni

    Subunit structurei

    Monomer.

    Structurei

    3D structure databases

    ProteinModelPortaliQ42962.
    SMRiQ42962. Positions 9-400.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni25 – 273Substrate bindingBy similarity
    Regioni64 – 674Substrate bindingBy similarity

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.Curated

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q42962-1 [UniParc]FASTAAdd to Basket

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    MAVKKSVGSL KEADLKGKRV FVRVDLNVPL DENFNITDDT RIRAAVPTIK    50
    YLMQHGSHVI LASHLGRPKG VTPKYSLKPL VPRLSELLGV EVKIANDSIG 100
    PEVEKLVAEI PEGGVLLLEN VRFYKEEEKN EPEFAKKLAS LADLYVNDAF 150
    GTAHRAHAST EGVAKYLKPA VAGFLMQKEL DYLVGAVANP QKPFAAIVGG 200
    SKVSSKIGVI ESLLEKVDVL LLGGGMIFTF YKAQGYAVGS SLVEEDKLDL 250
    ATSLMEKAKA KGVSLLLPTD VVIADKFAAD ANSKVVPASE IPDGWMGLDI 300
    GPDAIKSFGS ALDTTKTVIW NGPMGVFEFD KFAAGTEAIA KKLAELSGKG 350
    VTTIIGGGDS VAAVEKVGLA EKMSHISTGG GASLELLEGK PLPGVLALDD 400
    A 401
    Length:401
    Mass (Da):42,364
    Last modified:November 1, 1996 - v1
    Checksum:i4AD69E74F8F4CDED
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z48976 mRNA. Translation: CAA88840.1.
    PIRiT03661.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z48976 mRNA. Translation: CAA88840.1 .
    PIRi T03661.

    3D structure databases

    ProteinModelPortali Q42962.
    SMRi Q42962. Positions 9-400.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q42962.
    ProMEXi Q42962.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequences of cDNAs encoding the chloroplastic and cytosolic phosphoglycerate kinases from tobacco."
      Rao S.K., Bringloe D.H., Dyer T.A., Raines C.A., Bradbeer J.W.
      Plant Gene Register PGR95-090
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Samsun.
      Tissue: Leaf.

    Entry informationi

    Entry nameiPGKY_TOBAC
    AccessioniPrimary (citable) accession number: Q42962
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3