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Q42962 (PGKY_TOBAC) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase, cytosolic

EC=2.7.2.3
OrganismNicotiana tabacum (Common tobacco)
Taxonomic identifier4097 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer.

Subcellular location

Cytoplasm HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 401401Phosphoglycerate kinase, cytosolic HAMAP-Rule MF_00145
PRO_0000145871

Regions

Nucleotide binding357 – 3604ATP By similarity
Region25 – 273Substrate binding By similarity
Region64 – 674Substrate binding By similarity

Sites

Binding site411Substrate By similarity
Binding site1221Substrate By similarity
Binding site1551Substrate By similarity
Binding site2061ATP By similarity
Binding site2971ATP; via carbonyl oxygen By similarity
Binding site3281ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q42962 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 4AD69E74F8F4CDED

FASTA40142,364
        10         20         30         40         50         60 
MAVKKSVGSL KEADLKGKRV FVRVDLNVPL DENFNITDDT RIRAAVPTIK YLMQHGSHVI 

        70         80         90        100        110        120 
LASHLGRPKG VTPKYSLKPL VPRLSELLGV EVKIANDSIG PEVEKLVAEI PEGGVLLLEN 

       130        140        150        160        170        180 
VRFYKEEEKN EPEFAKKLAS LADLYVNDAF GTAHRAHAST EGVAKYLKPA VAGFLMQKEL 

       190        200        210        220        230        240 
DYLVGAVANP QKPFAAIVGG SKVSSKIGVI ESLLEKVDVL LLGGGMIFTF YKAQGYAVGS 

       250        260        270        280        290        300 
SLVEEDKLDL ATSLMEKAKA KGVSLLLPTD VVIADKFAAD ANSKVVPASE IPDGWMGLDI 

       310        320        330        340        350        360 
GPDAIKSFGS ALDTTKTVIW NGPMGVFEFD KFAAGTEAIA KKLAELSGKG VTTIIGGGDS 

       370        380        390        400 
VAAVEKVGLA EKMSHISTGG GASLELLEGK PLPGVLALDD A 

« Hide

References

[1]"Nucleotide sequences of cDNAs encoding the chloroplastic and cytosolic phosphoglycerate kinases from tobacco."
Rao S.K., Bringloe D.H., Dyer T.A., Raines C.A., Bradbeer J.W.
Plant Gene Register PGR95-090
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Samsun.
Tissue: Leaf.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z48976 mRNA. Translation: CAA88840.1.
PIRT03661.

3D structure databases

ProteinModelPortalQ42962.
SMRQ42962. Positions 9-400.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ42962.
ProMEXQ42962.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGKY_TOBAC
AccessionPrimary (citable) accession number: Q42962
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: June 11, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways